Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.33 |
| ▸ | GLA known ✓ | P06280 | 1/20 | 0.33 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL142660 | 0.96 | ALDH1A1 (0.40) | ALDH1A1CA4TSHRTDP1CA1 | |
| Iodide SCHEMBL9634755 | 0.92 | ALDH1A1 (0.38) | ALDH1A1CA4TSHRTDP1CA1 | |
| SCHEMBL8128335 | 0.92 | ALDH1A1 (0.38) | ALDH1A1CA4TSHRTDP1CA1 | |
| Isothiocyanate SCHEMBL9859883 | 0.78 | MIF (0.35) | ALDH1A1HPGDCYP3A4APP | |
| SCHEMBL9860014 | 0.78 | CES2 (0.32) | CES2CES1APP | |
| Hydrochloric Acid SCHEMBL10685854 | 0.72 | — | — | |
| SCHEMBL9166142 | 0.67 | — | — | |
| SCHEMBL9635964 | 0.67 | — | — | |
| SCHEMBL9168511 | 0.67 | — | — | |
| SCHEMBL74571 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104311588-B | Aggregation-induced emission molecule based on silicon fluorene and its preparation method and application | 武汉大学 | 2016-09-14 | — | — | CN | claimed |
| EP-1088004-B1 | PRODUCTION OF ZIEGLER-NATTA CATALYSTS | ATOFINA RES (BE) | 2004-06-30 | — | — | EP | claimed |
| US-6624110-B2 | Production of Ziegler-Natta catalysts | FINA RESEARCH, S.A. (BE) | 2003-09-23 | — | — | US | claimed |
| US-20010016553-A1 | Production of Ziegler-Natta catalysts | FINA RESEARCH, S.A., A CORPORATION OF THE COUNTRY OF BELGIUM | 2001-08-23 | — | — | US | claimed |
| EP-0952162-A1 | Production of Ziegler-Natta catalysts | FINA RESEARCH S.A. (BE) | 1999-10-27 | — | — | EP | claimed |
| CN-119143972-A | Blue heat-induced delayed fluorescent polymer and preparation method and application thereof | 中国科学院长春应用化学研究所 | 2024-12-17 | — | — | CN | disclosed |
| CN-108383980-A | A kind of thermal induction delayed fluorescence polymer and preparation method thereof of main chain silicon containing diphenyl and carbazole unit | 中国科学院长春应用化学研究所 | 2018-08-10 | — | — | CN | disclosed |
| EP-2103642-B1 | Siloxane composite based light-weight optical lenses | KOITO MFG CO LTD (JP) | 2018-03-07 | — | — | EP | disclosed |
| CN-104311588-B | Aggregation-induced emission molecule based on silicon fluorene and its preparation method and application | 武汉大学 | 2016-09-14 | — | — | CN | disclosed |
| CN-105669902-A | Novel cycloolefin copolymer catalyst and synthetic method thereof | 魏东初 | 2016-06-15 | — | — | CN | disclosed |
| US-20160009830-A1 | SUPPORTED POLYOLEFIN CATALYST AND PREPARATION AND APPLICATION THEREOF | PETROCHINA COMPANY LIMITED (CN) | 2016-01-14 | — | — | US | disclosed |
| US-8318887-B2 | Siloxane composite-based light-weight optical lenses | KOITO MANUFACTURING CO., LTD. (JP) | 2012-11-27 | — | — | US | disclosed |
| EP-2103642-A1 | Siloxane composite based light-weight optical lenses | EPG (Engineered nanoProducts Germany) AG (DE) | 2009-09-23 | — | — | EP | disclosed |
| US-20070298085-A1 | Skin Sanitizing Object | THE CLOROX COMPANY | 2007-12-27 | — | — | US | disclosed |
| EP-1088004-B1 | PRODUCTION OF ZIEGLER-NATTA CATALYSTS | ATOFINA RES (BE) | 2004-06-30 | — | — | EP | disclosed |
| US-6624110-B2 | Production of Ziegler-Natta catalysts | FINA RESEARCH, S.A. (BE) | 2003-09-23 | — | — | US | disclosed |
| US-20010016553-A1 | Production of Ziegler-Natta catalysts | FINA RESEARCH, S.A., A CORPORATION OF THE COUNTRY OF BELGIUM | 2001-08-23 | — | — | US | disclosed |
| EP-1088004-A1 | PRODUCTION OF ZIEGLER-NATTA CATALYSTS | FINA RESEARCH S.A. (BE) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999055740-A1 | PRODUCTION OF ZIEGLER-NATTA CATALYSTS | FINA RESEARCH S.A. (BE) | 1999-11-04 | — | — | WO | disclosed |
| EP-0952162-A1 | Production of Ziegler-Natta catalysts | FINA RESEARCH S.A. (BE) | 1999-10-27 | — | — | EP | disclosed |