Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 known ✓ | P27487 | 1/20 | 0.42 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.35 |
| ▸ | TTR known ✓ | P02766 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | TPMT | P51580 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11671966 | 1.00 | DPP4 (0.42) | DPP4HTTCYP1A2CES2CES1 | |
| SCHEMBL4899263 | 0.96 | DPP4 (0.43) | DPP4HTTCYP1A2CES2CES1 | |
| SCHEMBL70425 | 0.96 | DPP4 (0.43) | DPP4HTTCYP1A2CES2CES1 | |
| SCHEMBL205832 | 0.93 | HTT (0.45) | DPP4HTTCYP1A2CES2CES1 | |
| Hydrochloric Acid SCHEMBL29253982 | 0.93 | DPP4 (0.42) | DPP4HTTCYP1A2CES2CES1 | |
| Hydrochloric Acid SCHEMBL10715453 | 0.90 | HTT (0.48) | DPP4HTTCYP1A2CES2CES1 | |
| SCHEMBL10617916 | 0.90 | HTT (0.43) | DPP4HTTCYP1A2CES2CES1 | |
| SCHEMBL6903601 | 0.90 | HTT (0.48) | DPP4HTTCYP1A2CES2CES1 | |
| SCHEMBL6227879 | 0.90 | HTT (0.43) | DPP4HTTCYP1A2CES2CES1 | |
| SCHEMBL1157937 | 0.90 | HTT (0.43) | DPP4HTTCYP1A2CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1961729-B1 | METHOD FOR PRODUCING TETRAFLUOROTEREPHTHALIC ACID DIFLUORIDE | SUMITOMO CHEMICAL CO (JP) | 2012-09-26 | — | — | EP | claimed |
| US-8017798-B2 | Method for producing tetrafluoroterephthalic acid difluoride | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-09-13 | — | — | US | claimed |
| US-20090227810-A1 | METHOD FOR PRODUCING TETRAFLUOROTEREPHTHALIC ACID DIFLUORIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-09-10 | — | — | US | claimed |
| EP-1961729-A1 | METHOD FOR PRODUCING TETRAFLUOROTEREPHTHALIC ACID DIFLUORIDE | Sumitomo Chemical Company, Limited (JP) | 2008-08-27 | — | — | EP | claimed |
| US-11512037-B2 | Process for producing dimethyl 2,3,5,6-tetrachloro-1,4-benzenedicarboxylate | SDS BIOTECH K.K. (JP) | 2022-11-29 | — | — | US | disclosed |
| US-20220267244-A1 | PROCESS FOR PRODUCING DIMETHYL 2,3,5,6-TETRACHLORO-1,4-BENZENEDICARBOXYLATE | SDS BIOTECH K.K. (JP) | 2022-08-25 | — | — | US | disclosed |
| CN-101610988-B | Method for producing 4-methyl-2,3,5,6-tetrafluorobenzyl alcohol | SUMITOMO CO LTD | 2013-04-17 | — | — | CN | disclosed |
| CN-101321720-B | Method for producing tetrafluoroterephthalic acid difluoride | SUMITOMO CHEMICAL CO | 2012-12-26 | — | — | CN | disclosed |
| EP-1961729-B1 | METHOD FOR PRODUCING TETRAFLUOROTEREPHTHALIC ACID DIFLUORIDE | SUMITOMO CHEMICAL CO (JP) | 2012-09-26 | — | — | EP | disclosed |
| US-8017798-B2 | Method for producing tetrafluoroterephthalic acid difluoride | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-09-13 | — | — | US | disclosed |
| US-8017798-B2 | Method for producing tetrafluoroterephthalic acid difluoride | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-09-13 | — | — | US | disclosed |
| US-20090227810-A1 | METHOD FOR PRODUCING TETRAFLUOROTEREPHTHALIC ACID DIFLUORIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-09-10 | — | — | US | disclosed |
| WO-2007066529-A1 | METHOD FOR PRODUCING TETRAFLUOROTEREPHTHALIC ACID DIFLUORIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-14 | — | — | WO | disclosed |
| WO-2007066532-A1 | METHOD FOR PRODUCING TETRAFLUOROTEREPHTHALIC ACID DIFLUORIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-14 | — | — | WO | disclosed |
| EP-0112927-B1 | RESIN FOR LENS WITH HIGH REFRACTIVE INDEX AND LENS COMPOSED OF IT | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1987-02-11 | — | — | EP | disclosed |
| US-4522993-A | COPOLYMER HAVING UNITS FROM A BIS-ALLYL HALOGENATED BENZENE DICARBOXYLATE | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1985-06-11 | — | — | US | disclosed |
| EP-0112927-A1 | RESIN FOR LENS WITH HIGH REFRACTIVE INDEX AND LENS COMPOSED OF IT | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1984-07-11 | — | — | EP | disclosed |
| US-4310680-A | METAL OR METAL COMPOUND CATALYST | DYNAMIT NOBEL AG (DE) | 1982-01-12 | — | — | US | disclosed |
| US-4172938-A | Process for producing polyamides with lactam or urea solvent and CaCl2 | TEIJIN LIMITED (JP) | 1979-10-30 | — | — | US | disclosed |
| US-4033754-A | HERBICIDES | NIPPON SODA COMPANY LIMITED (JA) | 1977-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220267244-A1 | PROCESS FOR PRODUCING DIMETHYL 2,3,5,6-TETRACHLORO-1,4-BENZENEDICARBOXYLATE | PKD1, PKD2, BCKDK | DPP4 2309/4885CA2 12/4885TTR 911/4885 |
| US-11512037-B2 | Process for producing dimethyl 2,3,5,6-tetrachloro-1,4-benzenedicarboxylate | PKD1, PKD2, BCKDK | DPP4 2309/4885CA2 12/4885TTR 911/4885 |
| US-20090227810-A1 | METHOD FOR PRODUCING TETRAFLUOROTEREPHTHALIC ACID DIFLUORIDE | DDT, DGKA, FGFR1 | DPP4 2924/4885CA2 1065/4885TTR 627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.