Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Nornitrogen Mustard. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nornitrogen Mustard SCHEMBL1332213 | 1.00 | — | — | |
| Nornitrogen Mustard SCHEMBL27512643 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL9008650 | 0.96 | KDM4E (0.41) | — | |
| Nornitrogen Mustard SCHEMBL24674 | 0.95 | — | — | |
| Nornitrogen Mustard SCHEMBL2064862 | 0.91 | — | — | |
| SCHEMBL1311496 | 0.91 | LMNA (0.38) | — | |
| Nornitrogen Mustard SCHEMBL14636056 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL7038936 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL27885719 | 0.83 | — | — | |
| Nornitrogen Mustard SCHEMBL10698890 | 0.83 | ALDH1A1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1981 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250302850-A1 | STABLE READY TO USE CYCLOPHOSPHAMIDE LIQUID FORMULATIONS | INGENUS PHARMACEUTICALS, LLC (US) | 2025-10-02 | — | — | US | claimed |
| US-12329767-B2 | Stable ready to use cyclophosphamide liquid formulations | INGENUS PHARMACEUTICALS, LLC (US) | 2025-06-17 | — | — | US | claimed |
| CN-120118253-A | Oxygen-permeable silicon hydrogel material for contact lenses and preparation method thereof | 新中佳(广州)技术有限公司 | 2025-06-10 | — | — | CN | claimed |
| CN-120041883-A | Cationic polymer coated copper-based catalyst and preparation method and application thereof | 江南大学 | 2025-05-27 | — | — | CN | claimed |
| CN-119954675-A | Rhein-nitrogen mustard compound and application thereof in preparation of anticancer drugs | 广西国际壮医医院 | 2025-05-09 | — | — | CN | claimed |
| CN-119708463-A | Polymer antibacterial agent, antibacterial nylon material, and preparation methods and applications thereof | 中国科学院长春应用化学研究所 | 2025-03-28 | — | — | CN | claimed |
| CN-119462566-A | Preparation method of 1-cyclopropyl piperazine | 安徽皓元药业有限公司 | 2025-02-18 | — | — | CN | claimed |
| CN-118595440-B | Bearing prepared from composite material | 广东韶铸精锻有限公司 | 2025-01-24 | — | — | CN | claimed |
| CN-119285930-A | Zwitterionic polycondensation fulvic acid corrosion inhibitor and preparation method thereof | 陕西科技大学 | 2025-01-10 | — | — | CN | claimed |
| CN-118878503-A | Alpha 1A receptor blocker and preparation method thereof | 江苏联环药业股份有限公司 | 2024-11-01 | — | — | CN | claimed |
| WO-2011106545-A1 | POLYIMIDAZOLES FOR USE AS BILE ACID SEQUESTRANTS | RELYPSA, INC. (US) | 2011-09-01 | — | — | WO | claimed |
| US-20100254935-A1 | Amine condensation polymers as phosphate sequestrants | GENZYME CORPORATION (US) | 2010-10-07 | — | — | US | claimed |
| EP-2016114-A2 | AMINE CONDENSATION POLYMERS AS PHOSPHATE SEQUESTRANTS | Genzyme Corporation (US) | 2009-01-21 | — | — | EP | claimed |
| US-20080085259-A1 | Amine condensation polymers as phosphate sequestrants | GENZYME CORPORATION | 2008-04-10 | — | — | US | claimed |
| EP-1888559-A2 | PIPERAZINE-PIPERIDINE ANTAGONISTS AND AGONISTS OF THE 5-HT1A RECEPTOR | Wyeth a Corporation of the State of Delaware (US) | 2008-02-20 | — | — | EP | claimed |
| WO-2007130463-A2 | AMINE CONDENSATION POLYMERS AS PHOSPHATE SEQUESTRANTS | GENZYME CORPORATION (US) | 2007-11-15 | — | — | WO | claimed |
| WO-2007049124-A1 | METHOD OF MAKING 8-FLUORO-NAPHTHALEN-1-YLAMINE AND RELATED COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2007-05-03 | — | — | WO | claimed |
| US-20070027160-A1 | 5-fluoro-8-(4-(4-(6-methoxyquinolin-8-yl)piperazin-1-yl)piperidin-1-yl)quinoline; central nervous system disorders, such as cognition disorders, anxiety disorders, depression and sexual dysfunction | WYETH (US) | 2007-02-01 | — | — | US | claimed |
| WO-2006135839-A2 | PIPERAZINE-PIPERIDINE ANTAGONISTS AND AGONISTS OF THE 5-HT1A RECEPTOR | WYETH (US) | 2006-12-21 | — | — | WO | claimed |
| US-20060281926-A1 | Synthesis of 2-alkylcysteine via phase transfer catalysis | GIMI RAYOMAND H | 2006-12-14 | — | — | US | claimed |