Ea-230

Ea-230

SCHEMBL29360663

CC(C)[C@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)N)C(=O)O

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NOD1 Q9Y239 1/20 0.44
▸ GLO1 Q04760 1/20 0.40
▸ BMP1 P13497 1/20 0.39
▸ PTGS1 P23219 1/20 0.36
▸ GSTK1 Q9Y2Q3 1/20 0.36
▸ DPP4 P27487 1/20 0.35
▸ DPP8 Q6V1X1 1/20 0.35
▸ DPP9 Q86TI2 1/20 0.35
▸ ECE1 P42892 2/20 0.35
▸ FURIN P09958 1/20 0.34
▸ ALOX15 P16050 1/20 0.34
▸ BLM P54132 1/20 0.34
▸ PMP22 Q01453 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ SDCBP O00560 2/20 0.34
▸ SDC2 P34741 2/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ MAGI3 Q5TCQ9 1/20 0.33
▸ EPHX2 P34913 1/20 0.33
▸ NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30920966 0.85 NOD1 (0.52) NOD1GLO1BMP1PTGS1GSTK1
SCHEMBL30832635 0.85 NOD1 (0.49) NOD1GLO1BMP1PTGS1GSTK1
SCHEMBL31039964 0.84 BACE1 (0.46) GLO1PTGS1GSTK1DPP4DPP8
SCHEMBL30558188 0.84 DPP4 (0.48) NOD1GLO1PTGS1GSTK1DPP4
SCHEMBL3358182 0.83 GLO1 (0.48) NOD1GLO1BMP1PTGS1GSTK1
SCHEMBL29349612 0.82 ALDH1A1 (0.42) SDCBPSDC2ALDH1A1EPHX2NPSR1
SCHEMBL11841346 0.82 OPRM1 (0.46) FURIN
SCHEMBL11832854 0.82 OPRM1 (0.46) FURIN
SCHEMBL7614754 0.81 NOD1 (0.52) NOD1GLO1BMP1PTGS1GSTK1
SCHEMBL7614745 0.81 NOD1 (0.52) NOD1GLO1BMP1PTGS1GSTK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260027062-A1 IMPROVED ORAL PHARMACEUTICAL FORMULATIONS OF THERAPEUTIC PEPTIDES AND PROTEINS CYPRUMED GMBH (AT) 2026-01-29 — — US claimed
EP-4486366-A1 IMPROVED ORAL PHARMACEUTICAL FORMULATIONS OF THERAPEUTIC PEPTIDES AND PROTEINS Cyprumed GmbH (AT) 2025-01-08 — — EP claimed
CN-119156221-A Improved oral pharmaceutical formulations of therapeutic peptides and proteins 西普鲁梅有限公司 2024-12-17 — — CN claimed
WO-2023166179-A1 IMPROVED ORAL PHARMACEUTICAL FORMULATIONS OF THERAPEUTIC PEPTIDES AND PROTEINS CYPRUMED GMBH (AT) 2023-09-07 — — WO claimed
US-12624002-B2 Dimers for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-05-12 — — US disclosed
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 — — US disclosed
US-12595233-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-07 — — US disclosed
US-20260070894-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-03-12 — — US disclosed
US-20260027062-A1 IMPROVED ORAL PHARMACEUTICAL FORMULATIONS OF THERAPEUTIC PEPTIDES AND PROTEINS CYPRUMED GMBH (AT) 2026-01-29 — — US disclosed
US-20250295587-A1 COMPLEX LIPID NANOPARTICLES ENCAPSULATING POLYPEPTIDES AND USES THEREOF SAIL BIOMEDICINES, INC. 2025-09-25 — — US disclosed
US-12351573-B2 Compounds for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2025-07-08 — — US disclosed
US-12202836-B2 Bicyclic-fused heteroaryl or aryl compounds PFIZER INC. (US) 2025-01-21 — — US disclosed
US-20220152139-A1 PLANT MESSENGER PACKS ENCAPSULATING POLYPEPTIDES AND USES THEREOF FLAGSHIP PIONEERING INNOVATIONS VI, LLC 2022-05-19 — — US disclosed
US-11324736-B2 Method of Treating Focal Segmental Glomerulosclerosis CHEMOCENTRYX, INC. (US) 2022-05-10 — — US disclosed
WO-2022069576-A1 AUTOPHAGY-INHIBITING PEPTIDE AND ORGANIC ACID SALT THEREOF ADDRESSING ISSUES OF VASCULAR PERMEABILITY BIOTEMPT B.V. (NL) 2022-04-07 — — WO disclosed
EP-3966201-A1 THIOSEMICARBAZATES AND USES THEREOF The Feinstein Institutes for Medical Research (US) 2022-03-16 — — EP disclosed
EP-3966223-A1 PEPTIDOMIMETIC AGENTS, SYNTHESIS AND USES THEREOF The Feinstein Institutes for Medical Research (US) 2022-03-16 — — EP disclosed
CN-114126619-A Compounds for the synthesis of peptidomimetics 范因斯坦医学研究院 2022-03-01 — — CN disclosed
EP-3536685-B1 BICYCLIC-FUSED HETEROARYL OR ARYL COMPOUNDS AND THEIR USE AS IRAK4 INHIBITORS PFIZER (US) 2022-02-16 — — EP disclosed
US-20220024991-A1 ENGINEERED FLAGELLIN-DERIVED COMPOSITIONS AND USES GENOME PROT INC (US) 2022-01-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12351573-B2 Compounds for use in synthesis of peptidomimetics DNPEP, NPEPPS, PAM NOD1 1617/4885GLO1 3225/4885BMP1 249/4885
US-12624002-B2 Dimers for use in synthesis of peptidomimetics GLUL, ARGLU1, ASNS NOD1 872/4885GLO1 207/4885BMP1 877/4885
US-20260070894-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS NPR1, NGLY1, DDAH1 NOD1 305/4885GLO1 947/4885BMP1 123/4885
US-12595233-B2 Thiosemicarbazates and uses thereof TST, THRB, HSPB1 NOD1 218/4885GLO1 923/4885BMP1 1447/4885
US-20260027062-A1 IMPROVED ORAL PHARMACEUTICAL FORMULATIONS OF THERAPEUTIC PEPTIDES AND PROTEINS ADM2, TAS2R42, ACP1 NOD1 1861/4885GLO1 2874/4885BMP1 135/4885
US-12202836-B2 Bicyclic-fused heteroaryl or aryl compounds TTR, TYR, ABL1 NOD1 698/4885GLO1 3315/4885BMP1 3346/4885
US-11324736-B2 Method of Treating Focal Segmental Glomerulosclerosis SLC5A1, PTGFR, HPGDS NOD1 2509/4885GLO1 3884/4885BMP1 352/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT NOD1 679/4885GLO1 317/4885BMP1 1541/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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