Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.32 |
| ▸ | GLA known ✓ | P06280 | 1/20 | 0.32 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29742149 | 0.96 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1CA1CA2 | |
| Ammonia Solution, Strong SCHEMBL10353912 | 0.96 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1CA1CA2 | |
| SCHEMBL1679860 | 0.93 | ALDH1A1 (0.40) | ALDH1A1TSHRTDP1CA1CA2 | |
| SCHEMBL2809108 | 0.89 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1CA1CA2 | |
| SCHEMBL11851387 | 0.89 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1CA1CA2 | |
| SCHEMBL10560031 | 0.89 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1CA1CA2 | |
| SCHEMBL7027927 | 0.89 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1CA1CA2 | |
| Ethylene SCHEMBL6059829 | 0.86 | ALDH1A1 (0.35) | ALDH1A1TSHRTDP1CA1CA2 | |
| Ethyne SCHEMBL2390599 | 0.86 | ALDH1A1 (0.35) | ALDH1A1TSHRTDP1CA1CA2 | |
| Ammonia Solution, Strong SCHEMBL31046202 | 0.78 | BBOX1 (0.32) | ALDH1A1BBOX1EHMT2EHMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114854017-B | Polymer with main chain containing thioether group and synthesis method thereof | 浙江大学 | 2023-02-07 | — | — | CN | claimed |
| CN-115197422-A | Preparation method of aliphatic polythioether | 华东师范大学 | 2022-10-18 | — | — | CN | claimed |
| CN-114854017-A | Polymer with main chain containing thioether group and synthesis method thereof | 浙江大学 | 2022-08-05 | — | — | CN | claimed |
| CN-110804193-B | 3D printing method of hydrogel support | 南方医科大学南方医院 | 2022-02-11 | — | — | CN | claimed |
| CN-114181259-B | Amino bisphenol tetradentate chromium (III) catalyst, preparation and application thereof | 杭州凯艳新材料科技有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-117887109-A | Crosslinked polymer, synthesis method of crosslinked polymer and solid polymer electrolyte | 上海交通大学 | 2024-04-16 | — | — | CN | disclosed |
| CN-117362620-A | Carbon dioxide-based copolymer and preparation method and application thereof | 中国科学院长春应用化学研究所 | 2024-01-09 | — | — | CN | disclosed |
| CN-115975166-A | Aliphatic polycarbonate terpolymer and preparation method thereof | 岳阳昌德新材料有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-115960343-A | High-activity oligomer catalyst and method for preparing alkylene oxide and cyclic anhydride alternating copolymer by using same | 大连理工大学 | 2023-04-14 | — | — | CN | disclosed |
| CN-115819746-A | Full-biodegradable macromolecular compatibilizer, preparation method and application thereof | 烟台大学 | 2023-03-21 | — | — | CN | disclosed |
| CN-114854017-B | Polymer with main chain containing thioether group and synthesis method thereof | 浙江大学 | 2023-02-07 | — | — | CN | disclosed |
| CN-115286781-A | Electron-withdrawing group polycarbonate ether polyol and efficient preparation method thereof | 中国科学院长春应用化学研究所 | 2022-11-04 | — | — | CN | disclosed |
| CN-115057878-A | Main chain polyester type oligomeric porphyrin metal complex as well as preparation method and application thereof | 中国科学院长春应用化学研究所 | 2022-09-16 | — | — | CN | disclosed |
| CN-114854017-A | Polymer with main chain containing thioether group and synthesis method thereof | 浙江大学 | 2022-08-05 | — | — | CN | disclosed |
| CN-110804193-B | 3D printing method of hydrogel support | 南方医科大学南方医院 | 2022-02-11 | — | — | CN | disclosed |