Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 known ✓ | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 known ✓ | P32297 | 1/20 | 0.46 |
| ▸ | SIGMAR1 known ✓ | Q99720 | 2/20 | 0.43 |
| ▸ | HTR2A known ✓ | P28223 | 4/20 | 0.42 |
| ▸ | HRH1 known ✓ | P35367 | 3/20 | 0.42 |
| ▸ | KCNH2 known ✓ | Q12809 | 2/20 | 0.41 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 known ✓ | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 known ✓ | P41145 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28700501 | 1.00 | CHRNB2 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL28712176 | 1.00 | CHRNB2 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL28696451 | 1.00 | CHRNB2 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL28709728 | 1.00 | CHRNB2 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL3161458 | 1.00 | CHRNB2 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7782753 | 1.00 | CHRNB2 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL439139 | 1.00 | CHRNB2 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL19809906 | 1.00 | CHRNB2 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL28713675 | 1.00 | CHRNB2 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL28704241 | 1.00 | CHRNB2 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 923 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115845924-B | Catalyst for biogas desulfurization and preparation method and application thereof | 河北络合科技有限公司 | 2024-08-02 | — | — | CN | claimed |
| CN-116574220-A | Superhard dental model photo-curing 3D printing resin material and preparation method thereof | 湖南增材精准医疗研究院有限公司 | 2023-08-11 | — | — | CN | claimed |
| CN-116444245-A | Concrete slurry and preparation method thereof | 石家庄金隅混凝土有限公司 | 2023-07-18 | — | — | CN | claimed |
| CN-114289729-B | Thiol-modified nano gold colloid liquid and preparation method and application thereof | 广东粤港澳大湾区国家纳米科技创新研究院 | 2023-04-25 | — | — | CN | claimed |
| CN-113666680-B | Concrete slurry and preparation method thereof | 广东工建混凝土有限公司 | 2022-07-19 | — | — | CN | claimed |
| CN-113530242-B | Environment-friendly waterproof heat-preservation construction method | 湖北淇源新材料科技有限公司 | 2022-05-10 | — | — | CN | claimed |
| CN-114289729-A | Thiol-modified nanogold colloidal fluid and preparation method and application thereof | 广东粤港澳大湾区国家纳米科技创新研究院 | 2022-04-08 | — | — | CN | claimed |
| CN-113881177-A | Antibacterial water-absorbing composite material, and preparation method and device thereof | 威高集团有限公司 | 2022-01-04 | — | — | CN | claimed |
| CN-113666680-A | Concrete slurry and preparation method thereof | 湖北淇源新材料科技有限公司 | 2021-11-19 | — | — | CN | claimed |
| CN-113530242-A | Environment-friendly waterproof heat-preservation construction method | 湖北淇源新材料科技有限公司 | 2021-10-22 | — | — | CN | claimed |
| US-7713859-B2 | Tin-silver solder bumping in electronics manufacture | ENTHONE INC. (US) | 2010-05-11 | — | — | US | claimed |
| JP-2009510255-A | — | — | 2009-03-12 | — | — | JP | claimed |
| EP-1946362-A2 | TIN-SILVER SOLDER BUMPING IN ELECTRONICS MANUFACTURE | ENTHONE, INCORPORATED (US) | 2008-07-23 | — | — | EP | claimed |
| WO-2007022075-A2 | TIN-SILVER SOLDER BUMPING IN ELECTRONICS MANUFACTURE | ENTHONE INC. (US) | 2007-02-22 | — | — | WO | claimed |
| US-20070037377-A1 | TIN-SILVER SOLDER BUMPING IN ELECTRONICS MANUFACTURE | ENTHONE INC. (US) | 2007-02-15 | — | — | US | claimed |
| CN-1883899-A | Cuprammonium wood protective agent | SHANGHAI DABUTONG WOOD INDUSTR (CN) | 2006-12-27 | — | — | CN | claimed |
| WO-2005000954-A1 | FLAME-RETARDANT SOOT-CONTAINING POLYURETHANE FOAMS | AKZO NOBEL N.V. (NL) | 2005-01-06 | — | — | WO | claimed |
| EP-0566270-B1 | Coated recording sheets | XEROX CORP (US) | 1996-09-25 | — | — | EP | claimed |
| EP-0566270-A1 | Coated recording sheets | XEROX CORPORATION (US) | 1993-10-20 | — | — | EP | claimed |
| US-5212008-A | Coated recording sheets | XEROX CORPORATION (US) | 1993-05-18 | — | — | US | claimed |