Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 known ✓ | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 known ✓ | P32297 | 1/20 | 0.46 |
| ▸ | SIGMAR1 known ✓ | Q99720 | 2/20 | 0.43 |
| ▸ | HTR2A known ✓ | P28223 | 4/20 | 0.42 |
| ▸ | HRH1 known ✓ | P35367 | 3/20 | 0.42 |
| ▸ | KCNH2 known ✓ | Q12809 | 2/20 | 0.41 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 known ✓ | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 known ✓ | P41145 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28700501 | 1.00 | CHRNB2 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL28712176 | 1.00 | CHRNB2 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL28696451 | 1.00 | CHRNB2 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL28709728 | 1.00 | CHRNB2 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL3161458 | 1.00 | CHRNB2 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7782753 | 1.00 | CHRNB2 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL19809906 | 1.00 | CHRNB2 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL300585 | 1.00 | CHRNB2 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL28713675 | 1.00 | CHRNB2 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL28704241 | 1.00 | CHRNB2 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119012546-A | Method for directly electroplating printed circuit board | 上海电力大学 | 2024-11-22 | — | — | CN | claimed |
| WO-2024141224-A1 | ANHYDROUS COSMETIC COMPOSITION COMPRISING A CLAY, A WAX AND A HYDROCARBON ETHER OIL | L'OREAL (FR) | 2024-07-04 | — | — | WO | claimed |
| CN-117403291-A | Method for directly electroplating surface and hole of printed circuit board | 上海电力大学 | 2024-01-16 | — | — | CN | claimed |
| US-11718767-B2 | Chemical mechanical planarization composition for polishing oxide materials and method of use thereof | VERSUM MATERIALS US, LLC (US) | 2023-08-08 | — | — | US | claimed |
| CN-113293840-A | Municipal road structure and construction method thereof | 浙江嘉湖生态建设有限公司 | 2021-08-24 | — | — | CN | claimed |
| CN-112921679-A | Printing and dyeing auxiliary agent for dyeing natural pigment | 江苏四新界面剂科技有限公司 | 2021-06-08 | — | — | CN | claimed |
| CN-112127176-A | Dyeing agent for silk fabric spinning | 董平 | 2020-12-25 | — | — | CN | claimed |
| CN-108867220-B | Municipal road and construction method thereof | 四川先舟建设工程有限公司 | 2020-10-23 | — | — | CN | claimed |
| CN-110863374-A | Textile printing and dyeing auxiliary | 徐州玉兔纺织有限公司 | 2020-03-06 | — | — | CN | claimed |
| CN-106223070-A | A kind of vat auxiliary agent | 萧县凯奇化工科技有限公司 | 2016-12-14 | — | — | CN | claimed |
| EP-0566270-B1 | Coated recording sheets | XEROX CORP (US) | 1996-09-25 | — | — | EP | claimed |
| WO-1996021681-A1 | ABSORBENT FOAMS MADE FROM HIGH INTERNAL PHASE EMULSIONS USEFUL FOR ACQUIRING AND DISTRIBUTING AQUEOUS FLUIDS | THE PROCTER & GAMBLE COMPANY (US) | 1996-07-18 | — | — | WO | claimed |
| EP-0566270-A1 | Coated recording sheets | XEROX CORPORATION (US) | 1993-10-20 | — | — | EP | claimed |
| US-5212008-A | Coated recording sheets | XEROX CORPORATION (US) | 1993-05-18 | — | — | US | claimed |
| US-5137639-A | Method for purifying waste water using surface modified silica | PPG INDUSTRIES, INC. (US) | 1992-08-11 | — | — | US | claimed |
| EP-0151664-A1 | Toy car | NIKKO Co., Ltd. (JP) | 1985-08-21 | — | — | EP | claimed |
| EP-0046594-B1 | PHARMACEUTICAL COMPOSITION | Stout, Daniel W. (US) | 1984-11-14 | — | — | EP | claimed |
| US-4330551-A | ANALGESIC EMULSION OF CATIONIC AND NONIONIC SURFACTANT | SYNERGETICS CO. | 1982-05-18 | — | — | US | claimed |
| EP-0046594-A2 | Pharmaceutical composition | Stout, Daniel W. (US) | 1982-03-03 | — | — | EP | claimed |
| US-4143085-A | METHOD FOR ISOLATING LOW MOLECULAR WEIGHT POLYMER | SUMITOMO CHEMICAL CO., LTD. (JP) | 1979-03-06 | — | — | US | claimed |