Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16197980 | 0.74 | CTSD (0.31) | CTSD | |
| SCHEMBL22978326 | 0.74 | CTSD (0.31) | CTSD | |
| SCHEMBL2230540 | 0.69 | CTSD (0.43) | CTSD | |
| SCHEMBL3122693 | 0.69 | CTSD (0.32) | CTSD | |
| SCHEMBL28961651 | 0.67 | CTSD (0.38) | CTSD | |
| Hydrochloric Acid SCHEMBL8060241 | 0.67 | CTSD (0.33) | CTSD | |
| SCHEMBL19579927 | 0.63 | — | — | |
| SCHEMBL3409042 | 0.63 | CTSD (0.35) | CTSD | |
| SCHEMBL4652458 | 0.63 | CTSD (0.35) | CTSD | |
| Methylene Chloride SCHEMBL8847111 | 0.62 | CTSD (0.30) | CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461681-A | Iridium-catalyzed N-phenyl-7 azaindole derivative and preparation method thereof | 陕西科技大学 | 2021-10-01 | — | — | CN | claimed |
| US-10710948-B2 | Processes for preparing (R)-1-(5-chloro-[1,1″-biphenyl] -2-yl)-2,2,2-trifluoroethanol and 1-(5-chloro-[1,1″-biphenyl]-2-yl)-2,2,2-trifluoroethanone | ROIVANT SCIENCES GMBH (CH) | 2020-07-14 | — | — | US | claimed |
| EP-2187887-B1 | METHODS OF PREPARING 4-PHENYL-6-(2,2,2-TRIFLUORO-1-PHENYLETHOXY)PYRIMIDINE-BASED COMPOUNDS | LEXICON PHARMACEUTICALS INC (US) | 2017-11-15 | — | — | EP | claimed |
| US-20160257633-A1 | PROCESSES FOR PREPARING (R)-1-(5-CHLORO-[1,1`-BIPHENYL]-2-YL)-2,2,2-TRIFLUOROETHANOL AND 1-(5-CHLORO-[1,1`-BIPHENYL]-2-YL)-2,2,2-TRIFLUOROETHANONE | ALTAVANT SCIENCES GMBH (CH) | 2016-09-08 | — | — | US | claimed |
| EP-2576563-B1 | A NOVEL SYNTHETIC APPROACH TO ß-AMINOBUTYRYL SUBSTITUTED COMPOUNDS | LEK PHARMACEUTICALS (SI) | 2016-05-11 | — | — | EP | claimed |
| EP-2340253-B1 | PROCESSES FOR THE SELECTIVE AMINATION OF KETOMORPHINANS | MALLINCKRODT LLC (US) | 2013-11-13 | — | — | EP | claimed |
| US-8519133-B2 | Preparation of 6-alpha-amino N-substituted morphinans by catalytic hydrogen transfer | MALLINCKRODT LLC (US) | 2013-08-27 | — | — | US | claimed |
| US-8471023-B2 | Reductive amination of 6-keto normorphinans by catalytic hydrogen transfer | MALLINCKRODT LLC (US) | 2013-06-25 | — | — | US | claimed |
| WO-2013075679-A1 | A METHOD OF PRODUCING CINACALCET | ZENTIVA, K.S. (CZ) | 2013-05-30 | — | — | WO | claimed |
| US-20120316343-A1 | Reductive Amination of 6-Keto Morphinans by Catalytic Hydrogen Transfer | MALLINCKRODT LLC (US) | 2012-12-13 | — | — | US | claimed |
| EP-2152715-B1 | IMPROVED PROCESS FOR THE PREPARATION OF 6-ALPHA-HYDROXY-N-ALKYLATED OPIATES | MALLINCKRODT INC (US) | 2010-12-29 | — | — | EP | claimed |
| US-20100317683-A1 | Preparation of 6-Alpha-Amino N-Substituted Morphinans by Catalytic Hydrogen Transfer | MALLINCKRODT INC. (US) | 2010-12-16 | — | — | US | claimed |
| EP-4463230-A1 | HALF-SANDWICH TRANSITION METAL COMPLEXES AND USES THEREOF | Debreceni Egyetem (HU) | 2024-11-20 | — | — | EP | disclosed |
| WO-2023041947-A1 | HALF-SANDWICH TRANSITION METAL COMPLEXES AND USES THEREOF | DEBRECENI EGYETEM (HU) | 2023-03-23 | — | — | WO | disclosed |
| US-11273168-B2 | Methods of treating anxiety by administering a substituted quinolone | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2022-03-15 | — | — | US | disclosed |
| US-20210309687-A1 | PRMT5 INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2021-10-07 | — | — | US | disclosed |
| US-20110071300-A1 | One-Pot Preparation of Hexahydroisoquinolines from Dihydroisoquinolines | MALLINCKRODT INC. (US) | 2011-03-24 | — | — | US | disclosed |
| US-20100317683-A1 | Preparation of 6-Alpha-Amino N-Substituted Morphinans by Catalytic Hydrogen Transfer | MALLINCKRODT INC. (US) | 2010-12-16 | — | — | US | disclosed |
| US-20100317861-A1 | Remove Amination of 6-Keto Normorphinans by Catalytic Hydrogen Transfer | MALLINCKRODT INC. (US) | 2010-12-16 | — | — | US | disclosed |
| US-20100034733-A1 | CATALYST FOR DECOMPOSITION OF FORMIC ACID, METHOD FOR DECOMPOSING FORMIC ACID, PROCESS FOR PRODUCING HYDROGEN, APPARATUS FOR PRODUCING AND DECOMPOSING FORMIC ACID, AND METHOD FOR STORING AND GENERATING HYDROGEN | OSAKA UNIVERSITY (JP) | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120316343-A1 | Reductive Amination of 6-Keto Morphinans by Catalytic Hydrogen Transfer | AADAT, KMO, KHK | CTSD 2474/4885 |
| US-11273168-B2 | Methods of treating anxiety by administering a substituted quinolone | CRH, MC2R, HTR3C | CTSD 4590/4885 |
| US-20100034733-A1 | CATALYST FOR DECOMPOSITION OF FORMIC ACID, METHOD FOR DECOMPOSING FORMIC ACID, PROCESS FOR PRODUCING HYDROGEN, APPARATUS FOR PRODUCING AND DECOMPOSING FORMIC ACID, AND METHOD FOR STORING AND GENERATING HYDROGEN | H1-0, HRH3, H1-4 | CTSD 803/4885 |
| US-20100317683-A1 | Preparation of 6-Alpha-Amino N-Substituted Morphinans by Catalytic Hydrogen Transfer | AADAT, GFPT1, ASNS | CTSD 2099/4885 |
| US-20100317861-A1 | Remove Amination of 6-Keto Normorphinans by Catalytic Hydrogen Transfer | OPRK1, AADAT, OPRD1 | CTSD 1432/4885 |
| US-10710948-B2 | Processes for preparing (R)-1-(5-chloro-[1,1″-biphenyl] -2-yl)-2,2,2-trifluoroethanol and 1-(5-chloro-[1,1″-biphenyl]-2-yl)-2,2,2-trifluoroethanone | TPH1, TPH2, HTR1A | CTSD 2712/4885 |
| US-20160257633-A1 | PROCESSES FOR PREPARING (R)-1-(5-CHLORO-[1,1`-BIPHENYL]-2-YL)-2,2,2-TRIFLUOROETHANOL AND 1-(5-CHLORO-[1,1`-BIPHENYL]-2-YL)-2,2,2-TRIFLUOROETHANONE | TPH1, TPH2, HTR1A | CTSD 2752/4885 |
| US-20210309687-A1 | PRMT5 INHIBITORS | PRMT5, PRMT1, PRMT6 | CTSD 4826/4885 |
| US-20110071300-A1 | One-Pot Preparation of Hexahydroisoquinolines from Dihydroisoquinolines | QDPR, QTRT1, DHPS | CTSD 3196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.