Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Urea. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urea SCHEMBL149939 | 1.00 | — | — | |
| Urea SCHEMBL28172273 | 1.00 | — | — | |
| Urea SCHEMBL11222744 | 1.00 | LMNA (0.86) | — | |
| Urea SCHEMBL6335244 | 1.00 | — | — | |
| Urea SCHEMBL6335243 | 1.00 | LMNA (0.86) | — | |
| Urea SCHEMBL11615119 | 1.00 | — | — | |
| Urea SCHEMBL464759 | 0.94 | — | — | |
| Urea SCHEMBL6361903 | 0.94 | — | — | |
| Urea SCHEMBL4797521 | 0.94 | — | — | |
| Urea SCHEMBL10948393 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119861155-A | Liquid chromatographic analysis method for detecting deamidation and isomerization ratio of antibody and application thereof | 上海药明合联生物技术有限公司 | 2025-04-22 | — | — | CN | claimed |
| CN-119080907-A | Vimentin purification method | 山东大学 | 2024-12-06 | — | — | CN | claimed |
| WO-2026107236-A1 | COMPOSITIONS AND METHODS FOR VACCINATION AGAINST MYCOBACTERIUM TUBERCULOSIS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2026-05-21 | — | — | WO | disclosed |
| CN-119861155-A | Liquid chromatographic analysis method for detecting deamidation and isomerization ratio of antibody and application thereof | 上海药明合联生物技术有限公司 | 2025-04-22 | — | — | CN | disclosed |
| CN-119080907-A | Vimentin purification method | 山东大学 | 2024-12-06 | — | — | CN | disclosed |
| US-11802879-B2 | Identification and quantification of conjugated peptides in antibody drug conjugates by mass spectrometry | WATERS TECHNOLOGIES CORPORATION (US) | 2023-10-31 | — | — | US | disclosed |
| CN-110437331-B | Method for improving inclusion body protein renaturation of smooth turtle shell serine protease inhibitor | 四川轻化工大学 | 2023-04-07 | — | — | CN | disclosed |
| EP-3423831-B1 | IDENTIFICATION AND QUANTIFICATION OF CONJUGATED PEPTIDES IN ANTIBODY DRUG CONJUGATES BY MASS SPECTROMETRY | WATERS TECHNOLOGIES CORP (US) | 2022-05-25 | — | — | EP | disclosed |
| EP-2666467-A1 | EXTRACT OF AQUATIC ANIMAL CARTILAGE | Hirosaki University (JP) | 2013-11-27 | — | — | EP | disclosed |
| US-20130310540-A1 | EXTRACT OF AQUATIC ANIMAL CARTILAGE | SUNSTAR INC. (JP) | 2013-11-21 | — | — | US | disclosed |
| US-8455526-B2 | Therapeutic use of imidazole-5-carboxylic acid derivatives | SHANGHAI ALLIST PHARMACEUTICALS, INC. (CN) | 2013-06-04 | — | — | US | disclosed |
| US-20100168193-A1 | THERAPEUTIC USE OF IMIDAZOLE-5-CARBOXYLIC ACID DERIVATIVES | SHANGHAI ALLIST PHARMACEUTICALS, INC. (CN) | 2010-07-01 | — | — | US | disclosed |
| EP-2157089-A1 | THE THERAPEUTIC USES OF IMIDAZOL-5-CARBOXYLIC ACID DERIVATIVES | Shanghai Allist Pharmaceutical., Inc. (CN) | 2010-02-24 | — | — | EP | disclosed |
| US-4321092-A | CONTAINING A COLOR ACCEPTING METAL CHLORIDE, UREA, THIOUREA OR DIPHENYLTHIOUREA | KORES HOLDING ZUG AG (CH) | 1982-03-23 | — | — | US | disclosed |