Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Urea. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.56 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.42 |
| ▸ | MAOA known ✓ | P21397 | 1/20 | 0.42 |
| ▸ | MAOB known ✓ | P27338 | 1/20 | 0.42 |
| ▸ | GLA known ✓ | P06280 | 1/20 | 0.39 |
| ▸ | CRBN known ✓ | Q96SW2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 7/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.86 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.86 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.86 |
| ▸ | BLM | P54132 | 5/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | LDHA | P00338 | 2/20 | 0.46 |
| ▸ | LDHB | P07195 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urea SCHEMBL149939 | 1.00 | — | — | |
| Urea SCHEMBL28172273 | 1.00 | — | — | |
| Urea SCHEMBL11222744 | 1.00 | LMNA (0.86) | LMNAALDH1A1TDP1OR51E2ACHE | |
| Urea SCHEMBL3222655 | 1.00 | — | — | |
| Urea SCHEMBL6335244 | 1.00 | — | — | |
| Urea SCHEMBL11615119 | 1.00 | — | — | |
| Urea SCHEMBL464759 | 0.94 | — | — | |
| Urea SCHEMBL6361903 | 0.94 | — | — | |
| Urea SCHEMBL4797521 | 0.94 | — | — | |
| Urea SCHEMBL10948393 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3291673-B1 | ANTIMICROBIAL COMPOSITIONS AND METHODS FOR REDUCING MICROBIAL CONTAMINATION | POLYVATION B V (NL) | 2025-07-23 | — | — | EP | claimed |
| CN-107750124-B | Antimicrobial compositions and methods for reducing microbial contamination | 波利维逊有限公司 | 2022-10-28 | — | — | CN | claimed |
| US-20220313598-A1 | Antimicrobial Compositions and Methods For Reducing Microbial Contamination | POLYVATION B.V. (NL) | 2022-10-06 | — | — | US | claimed |
| US-11291625-B2 | Antimicrobial compositions and methods for reducing microbial contamination | POLYVATION B.V. (NL) | 2022-04-05 | — | — | US | claimed |
| CN-102973540-B | Antiviral method and compositions | GOJO IND INC. (US) | 2015-08-19 | — | — | CN | claimed |
| CN-102973540-A | Antiviral method and composition | GOJO IND INC | 2013-03-20 | — | — | CN | claimed |
| CN-101460603-A | Cleansing bar compositions comprising a high level of water | PROCTER & GAMBLE (US) | 2009-06-17 | — | — | CN | claimed |
| CN-1318018-C | Topical antioxidant vitamin composition for skin care | COLGATE PALMOLIVE CO (US) | 2007-05-30 | — | — | CN | claimed |
| CN-1062899-C | Improved acylisethionate skin cleansing bar containing liquid polyols. and magnesium soap | PROCTER & GAMBLE (US) | 2001-03-07 | — | — | CN | claimed |
| CN-1043430-C | Mild personal cleansing bar composition with balanced surfactants, fatty acids, and paraffin wax | PROCTER & GAMBLE (US) | 1999-05-19 | — | — | CN | claimed |
| CN-1066779-A | Antimicrobial soft liquid surfactant skin cleanser | PROCTER & GAMBLE (US) | 1992-12-09 | — | — | CN | claimed |
| EP-3291673-B1 | ANTIMICROBIAL COMPOSITIONS AND METHODS FOR REDUCING MICROBIAL CONTAMINATION | POLYVATION B V (NL) | 2025-07-23 | — | — | EP | disclosed |
| US-12324430-B2 | Topical antiseptic system | Infection Containment Company, LLC (US) | 2025-06-10 | — | — | US | disclosed |
| EP-4192531-A1 | FORTIFIED SANITIZING COMPOSITION HAVING ANTIMICROBIAL CHARACTERISTICS | 2 V Industries, Inc. (US) | 2023-06-14 | — | — | EP | disclosed |
| CN-115702122-A | Use of chloramines and cationic polymers in water treatment | 巴克曼实验室国际公司 | 2023-02-14 | — | — | CN | disclosed |
| CN-1086847-A | Improve the human body that mixes the gegenion basis soap containing of soft property and processibility and clean cake soap | PROCTER & GAMBLE (US) | 1994-05-18 | — | — | CN | disclosed |
| CN-1076480-A | The mild soap-synbar of improvement | PROCTER & GAMBLE (US) | 1993-09-22 | — | — | CN | disclosed |
| CN-1073479-A | Mild cleansing bar composition with balanced composition | PROCTER & GAMBLE (US) | 1993-06-23 | — | — | CN | disclosed |
| CN-1063894-A | Be used for long chain alkyl sulfates and improve its binding system mashed and foam property for basic cake soap | PROCTER & GAMBLE (US) | 1992-08-26 | — | — | CN | disclosed |
| CN-1062759-A | The formation solid that makes with the rigid staggered network of carboxylic acid after the neutralization | PROCTER & GAMBLE (US) | 1992-07-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11291625-B2 | Antimicrobial compositions and methods for reducing microbial contamination | CUTA, VNN1, NACA | ACHE 3545/4885CA2 4382/4885MAOA 321/4885 |
| US-20220313598-A1 | Antimicrobial Compositions and Methods For Reducing Microbial Contamination | CUTA, VNN1, NACA | ACHE 3545/4885CA2 4382/4885MAOA 321/4885 |
| US-12324430-B2 | Topical antiseptic system | CUTA, TREH, NACA | ACHE 236/4885CA2 2982/4885MAOA 423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.