Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 known ✓ | P50406 | 1/20 | 0.46 |
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | CASP1 | P29466 | 5/20 | 0.52 |
| ▸ | THRB | P10828 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | TSHR | P16473 | 6/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7035695 | 1.00 | TDP1 (0.53) | TDP1MEN1KMT2ACASP1THRB | |
| Hydrochloric Acid SCHEMBL29391311 | 1.00 | TDP1 (0.53) | TDP1MEN1KMT2ACASP1THRB | |
| Hydrochloric Acid SCHEMBL1599797 | 1.00 | TDP1 (0.53) | TDP1MEN1KMT2ACASP1THRB | |
| Hydrochloric Acid SCHEMBL29893542 | 1.00 | TDP1 (0.53) | TDP1MEN1KMT2ACASP1THRB | |
| SCHEMBL62612 | 0.97 | — | — | |
| SCHEMBL29371552 | 0.97 | — | — | |
| Benzene SCHEMBL28308705 | 0.90 | TDP1 (0.50) | TDP1MEN1KMT2ACASP1THRB | |
| Hydrochloric Acid SCHEMBL28563060 | 0.90 | TDP1 (0.50) | TDP1MEN1KMT2ACASP1THRB | |
| Alcohol SCHEMBL15520191 | 0.84 | ALDH1A1 (0.47) | TDP1MEN1KMT2ACASP1THRB | |
| Urea SCHEMBL6586511 | 0.83 | TDP1 (0.52) | TDP1MEN1KMT2ACASP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115672267-B | Nitrogen-doped carbon material, preparation method thereof and application thereof in heavy metal ion adsorption | 无锡蓝海工程设计有限公司 | 2024-05-17 | — | — | CN | claimed |
| CN-117731792-A | Nucleolus targeting-based carbon dot nanocomposite and preparation method and application thereof | 山西医科大学 | 2024-03-22 | — | — | CN | claimed |
| CN-115672267-A | Nitrogen-doped carbon material, preparation thereof and application thereof in heavy metal ion adsorption | 无锡蓝海工程设计有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-111303455-B | Zwitterionic polymer hydrogel and preparation method and application method thereof | 常州大学 | 2022-12-06 | — | — | CN | claimed |
| CN-108328607-B | Ultra-small blue-green light dual-emission nitrogen and chlorine co-doped graphene quantum dot and preparation method thereof | 吉林师范大学 | 2021-05-11 | — | — | CN | claimed |
| CN-111303455-A | Amphoteric ion polymer hydrogel and preparation method and application method thereof | 常州大学 | 2020-06-19 | — | — | CN | claimed |
| CN-110649163-A | Perovskite solar cell with sandwich structure electron transport layer and preparation method | 吉林师范大学 | 2020-01-03 | — | — | CN | claimed |
| CN-110205125-A | Graphene quantum dot fluorescence probe material and preparation method thereof with cell nucleus targeting imaging | 上海大学 | 2019-09-06 | — | — | CN | claimed |
| CN-108219453-B | Preparation method of three-dimensional porous graphene/polyaniline composite material | 沈阳大学 | 2019-06-25 | — | — | CN | claimed |
| CN-109097032-A | The preparation method of carbon quantum dot fluorescent material and its application in copper ion detection | 上海大学 | 2018-12-28 | — | — | CN | claimed |
| CN-108219453-A | Preparation method of three-dimensional porous graphene/polyaniline composite material | 沈阳大学 | 2018-06-29 | — | — | CN | claimed |
| CN-1332203-C | Quick test method fro detecting clenbuterol hydrochloride in animal derived food | UNIV SHANGHAI JIAOTONG (CN) | 2007-08-15 | — | — | CN | claimed |
| CN-1766635-A | Quick test method fro detecting clenbuterol hydrochloride in animal derived food | UNIV SHANGHAI JIAOTONG (CN) | 2006-05-03 | — | — | CN | claimed |
| US-5443859-A | Reacting tetracarboxylic acid dianhydride, aromatic diamine, optionally polyamine, to form polyamic acid, forming film, imidizing to form polyimide, carbonizing in inert gas or vacuum to form carbon film with specifed properties | TOHO RAYON CO., LTD. (JP) | 1995-08-22 | — | — | US | claimed |
| US-5218166-A | Resolvating, replasticizing, evaporation to dryness of nitrocellulose; waterproof, stable powder; slurrying, casting | MEI CORPORATION (US) | 1993-06-08 | — | — | US | claimed |
| US-12138330-B2 | Hair coloring modification additive and related methods | PWAI, LLC (US) | 2024-11-12 | — | — | US | disclosed |
| CN-115672267-B | Nitrogen-doped carbon material, preparation method thereof and application thereof in heavy metal ion adsorption | 无锡蓝海工程设计有限公司 | 2024-05-17 | — | — | CN | disclosed |
| EP-0001246-A1 | Preparation of 2-(3'- or 4'-aminophenyl)-5(or 6)-aminobenzimidazoles | CASSELLA Aktiengesellschaft (DE) | 1979-04-04 | — | — | EP | disclosed |
| US-4002671-A | REDUCE SEBUM SECRETION ON SCALP OR SKIN | SOCIETE ANONYME DITE: L'OREAL (FR) | 1977-01-11 | — | — | US | disclosed |
| US-3960476-A | OXIDATION BASE | GHILARDI GIULIANA | 1976-06-01 | — | — | US | disclosed |