Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5672879 | 0.98 | TSHR (0.41) | TSHRTHRBHPGDALDH1A1TP53 | |
| SCHEMBL10483612 | 0.95 | TSHR (0.39) | TSHRTHRBHPGDALDH1A1TP53 | |
| Methylsulfanylmethane SCHEMBL10483608 | 0.93 | TSHR (0.38) | TSHRTHRBHPGDALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL14335997 | 0.89 | TSHR (0.33) | TSHRTHRB | |
| SCHEMBL7797605 | 0.88 | TSHR (0.34) | TSHRTHRBHPGD | |
| Hydrochloric Acid SCHEMBL717767 | 0.82 | THRB (0.37) | TSHRTHRBHPGDALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL717362 | 0.79 | TSHR (0.39) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL10787047 | 0.79 | TSHR (0.42) | TSHRTHRBHPGDALDH1A1TP53 | |
| Bromide SCHEMBL28769243 | 0.79 | THRB (0.37) | TSHRTHRBHPGDALDH1A1TP53 | |
| SCHEMBL23494150 | 0.78 | TSHR (0.42) | TSHRTHRBHPGDALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2720668-B1 | COSMETIC USE OF A FLOCCULANT POLYMER AS ANTIPERSPIRANT | OREAL (FR) | 2020-05-06 | — | — | EP | claimed |
| US-20070248551-A1 | Use as an Antiperspirant Agent of a Flocculating Water-Soluble Polymer; Cosmetic Process for Treating Perspiration | L'OREAL S.A. (FR) | 2007-10-25 | — | — | US | claimed |
| EP-1761241-A1 | USE AS AN ANTIPERSPIRANT AGENT OF A FLOCCULATING WATER-SOLUBLE POLYMER; COSMETIC PROCESS FOR TREATING PERSPIRATION | l'Oreal SA (FR) | 2007-03-14 | — | — | EP | claimed |
| WO-2005120448-A1 | USE AS AN ANTIPERSPIRANT AGENT OF A FLOCCULATING WATER-SOLUBLE POLYMER; COSMETIC PROCESS FOR TREATING PERSPIRATION | L'OREAL (FR) | 2005-12-22 | — | — | WO | claimed |
| US-5952394-A | A SYNERGISTIC ANTIDEPOSIT AGENT MIXTURE COMPRISING A PARTIALLY HYDROLYZED POLYVINYL ALCOHOL, A HIGH MOLECULAR WEIGHT GELATIN AND A CATIONIC POLYMER | BETZDEARBORN INC. (US) | 1999-09-14 | — | — | US | claimed |
| EP-0900299-A1 | COMPOSITIONS AND METHODS FOR INHIBITING DEPOSITS IN PULP AND PAPERMAKING SYSTEMS | BetzDearborn Inc (US) | 1999-03-10 | — | — | EP | claimed |
| EP-0900299-A4 | — | — | 1999-03-10 | — | — | EP | claimed |
| US-5723021-A | POLYVINYL ALCOHOL, GELATIN AND CATIONIC POLYMER | BETZDEARBORN INC. (US) | 1998-03-03 | — | — | US | claimed |
| WO-1997044519-A1 | COMPOSITIONS AND METHODS FOR INHIBITING DEPOSITS IN PULP AND PAPERMAKING SYSTEMS | BETZDEARBORN INC. (US) | 1997-11-27 | — | — | WO | claimed |
| CN-115298110-A | Cover tape for packaging electronic component and package | 大日本印刷株式会社 | 2022-11-04 | — | — | CN | disclosed |
| CN-114349901-A | Preparation method of flocculant | 常州市振邦化工制造有限公司 | 2022-04-15 | — | — | CN | disclosed |
| EP-2720668-B1 | COSMETIC USE OF A FLOCCULANT POLYMER AS ANTIPERSPIRANT | OREAL (FR) | 2020-05-06 | — | — | EP | disclosed |
| EP-1627107-B1 | METHOD FOR CONTROLLING PITCH AND STICKIES DEPOSITION | HERCULES INC (US) | 2009-09-16 | — | — | EP | disclosed |
| US-20070248551-A1 | Use as an Antiperspirant Agent of a Flocculating Water-Soluble Polymer; Cosmetic Process for Treating Perspiration | L'OREAL S.A. (FR) | 2007-10-25 | — | — | US | disclosed |
| US-5549832-A | PRECIPITATION OF METALS IN WITH ALKALINE COOLANT WITH SODIUM DIALKYLDITHIOCARBAMATE, BASIFICATION FOR COAGULATION, FILTRATION AND CLEANING | CENTURY MANUFACTURING COMPANY (US) | 1996-08-27 | — | — | US | disclosed |
| US-5169540-A | Treating an aqueous system to separate suspended material | BETZ LABORATORIES, INC. (US) | 1992-12-08 | — | — | US | disclosed |
| US-5100951-A | Stable blends of cationic water-in-oil emulsion polymers and cationic aqueous solution polymers | BETZ LABORATORIES, INC. (US) | 1992-03-31 | — | — | US | disclosed |
| EP-0083984-B1 | PREPARATION OF STABLE AQUEOUS DISPERSIONS OF POLYOLEFIN FIBRES | HERCULES INCORPORATED (US) | 1986-04-30 | — | — | EP | disclosed |
| US-4404314-A | CATIONIC COPOLYMER OF ACRYLAMIDE AND ACRYLATE | HERCULES INCORPORATED (US) | 1983-09-13 | — | — | US | disclosed |
| EP-0083984-A1 | Preparation of stable aqueous dispersions of polyolefin fibres | HERCULES INCORPORATED (US) | 1983-07-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070248551-A1 | Use as an Antiperspirant Agent of a Flocculating Water-Soluble Polymer; Cosmetic Process for Treating Perspiration | CUTA, TYR, PRKDC | TSHR 1046/4885THRB 3027/4885HPGD 3541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.