Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL7640201 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL5351702 | 0.85 | GABRA1 (0.32) | MEN1KMT2A | |
| SCHEMBL7046353 | 0.83 | GABRA1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL6065714 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL6515679 | 0.81 | MEN1 (0.30) | MEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL389033 | 0.81 | MEN1 (0.30) | MEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL272677 | 0.80 | — | — | |
| SCHEMBL3998599 | 0.80 | FAAH (0.33) | ALDH1A1 | |
| SCHEMBL7220661 | 0.79 | SLC6A2 (0.30) | — | |
| SCHEMBL4002684 | 0.79 | PDCD1 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2045304-B1 | POLYPROPYLENE-BASED ADHESIVE COMPOSITIONS | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2017-10-11 | — | — | EP | disclosed |
| US-8383731-B2 | Polypropylene-based adhesive compositions | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-02-26 | — | — | US | disclosed |
| US-20090156729-A1 | Polypropylene-Based Adhesive Compositions | EXXONMOBIL CHEMICAL PATENTS INC. | 2009-06-18 | — | — | US | disclosed |
| US-7521507-B2 | Polypropylene-based adhesive compositions | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2009-04-21 | — | — | US | disclosed |
| EP-2045304-A2 | Polypropylene-Based Adhesive Compositions | ExxonMobil Chemical Patents Inc. (US) | 2009-04-08 | — | — | EP | disclosed |
| EP-1311593-B1 | POLYPROPYLENE FILMS | EXXONMOBIL CHEM PATENTS INC (US) | 2009-01-07 | — | — | EP | disclosed |
| US-7235618-B2 | Using an organometallic catalyst and chain transfer agents | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-06-26 | — | — | US | disclosed |
| US-7205363-B2 | Using fluorided silica supported metallocene catalyst system and antistatic agent selected from polysulfone copolymer, polyamine, oil soluble sulfonic acid or mixture, for homo or copolymerization of propylene | EXXON MOBIL CHEMICAL PATENTS INC. (US) | 2007-04-17 | — | — | US | disclosed |
| EP-1315858-B1 | POLYPROPYLENE FIBERS AND FABRICS | EXXONMOBIL CHEM PATENTS INC (US) | 2007-02-07 | — | — | EP | disclosed |
| US-7098277-B2 | Polypropylene films | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-08-29 | — | — | US | disclosed |
| US-20020019507-A1 | Polypropylene-based adhesive compositions | EXXONMOBIL CHEMICAL PATENTS INC. | 2002-02-14 | — | — | US | disclosed |
| US-20010051698-A1 | Highly active supported catalyst compositions | EXXONMOBIL CHEMICAL PATENTS INC. | 2001-12-13 | — | — | US | disclosed |
| US-20010049331-A1 | SUPPORTED ORGANOMETALLIC CATALYSTS AND THEIR USE IN OLEFIN POLYMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. | 2001-12-06 | — | — | US | disclosed |
| US-20010044506-A1 | Crystalline homo/copolymers prepared using sequential or parallel metallocene dual catalyst system; broad, bimodal molecular weight distribution; biaxially oriented and non-oriented films; even stretch at low temperature | EXXONMOBIL CHEMICAL PATENTS INC. | 2001-11-22 | — | — | US | disclosed |
| US-20010039314-A1 | Propylene polymers for films | EXXONMOBIL CHEMICAL PATENTS INC. | 2001-11-08 | — | — | US | disclosed |
| US-6306960-B1 | AUTOMOBILES, ORGANOLEPTIC USES | EXXONMOBIL CHEMICAL PATENTS INC. | 2001-10-23 | — | — | US | disclosed |
| WO-2001036497-A1 | SUPPORTED ORGANOMETALLIC CATALYSTS AND THEIR USE IN OLEFIN POLYMERIZATION | EXXON CHEMICAL PATENTS INC. (US) | 2001-05-25 | — | — | WO | disclosed |
| WO-2001036499-A1 | PREPARATION OF SUPPORTED POLYMERIZATION CATALYSTS | EXXON CHEMICAL PATENTS INC. (US) | 2001-05-25 | — | — | WO | disclosed |
| WO-2001032757-A1 | FOAMABLE POLYPROPYLENE POLYMERS AND THEIR USE | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2001-05-10 | — | — | WO | disclosed |
| US-6174930-B1 | HOMOPOLYMERIZING PROPYLENE IN PRESENCE OF METALLOCENE AND FIRST AND SECOND CONCENTRATION OF CHAIN TRANSFER AGENT TO PRODUCE ISOTACTIC POLYPROPYLENE; FOAMING ISOTACTIC POLYPROPYLENE WITH FOAMING AGENT TO FORM FOAMED POLYPROPYLENE | EXXON CHEMICAL PATENTS, INC. | 2001-01-16 | — | — | US | disclosed |