Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 known ✓ | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 known ✓ | O43614 | 1/20 | 0.35 |
| ▸ | HDAC8 known ✓ | Q9BY41 | 1/20 | 0.32 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.91 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8527191 | 0.98 | TDP1 (0.95) | TDP1LMNAALDH1A1TSHRNT5E | |
| Water SCHEMBL5955686 | 0.98 | TDP1 (0.95) | TDP1LMNAALDH1A1TSHRNT5E | |
| Water SCHEMBL2898588 | 0.96 | TDP1 (0.91) | TDP1LMNAALDH1A1TSHRNT5E | |
| SCHEMBL25711 | 0.96 | TDP1 (1.00) | TDP1LMNAALDH1A1TSHRNT5E | |
| SCHEMBL31126649 | 0.96 | TDP1 (1.00) | TDP1LMNAALDH1A1TSHRNT5E | |
| SCHEMBL452529 | 0.96 | TDP1 (1.00) | TDP1LMNAALDH1A1TSHRNT5E | |
| SCHEMBL17476641 | 0.93 | TDP1 (0.95) | TDP1LMNAALDH1A1TSHRNT5E | |
| SCHEMBL2121269 | 0.93 | TDP1 (0.95) | TDP1LMNAALDH1A1TSHRNT5E | |
| Ammonia Solution, Strong SCHEMBL814454 | 0.93 | TDP1 (0.95) | TDP1LMNAALDH1A1TSHRNT5E | |
| SCHEMBL331672 | 0.93 | TDP1 (0.95) | TDP1LMNAALDH1A1TSHRNT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3959271-B1 | ELECTROPHORETIC PARTICLES, MEDIA, AND DISPLAYS AND PROCESSES FOR THE PRODUCTION THEREOF | E INK CORP (US) | 2024-08-07 | — | — | EP | disclosed |
| US-11520209-B2 | Electrophoretic particles, media, and displays and processes for the production thereof | E INK CORPORATION (US) | 2022-12-06 | — | — | US | disclosed |
| US-20200341342-A1 | ELECTROPHORETIC PARTICLES, MEDIA, AND DISPLAYS AND PROCESSES FOR THE PRODUCTION THEREOF | E INK CORPORATION | 2020-10-29 | — | — | US | disclosed |
| WO-2020219274-A1 | ELECTROPHORETIC PARTICLES, MEDIA, AND DISPLAYS AND PROCESSES FOR THE PRODUCTION THEREOF | E INK CORPORATION (US) | 2020-10-29 | — | — | WO | disclosed |
| EP-1393122-B1 | ELECTROPHORETIC PARTICLES | E INK CORP (US) | 2018-03-28 | — | — | EP | disclosed |
| US-20090009852-A1 | ELECTROPHORETIC PARTICLES AND PROCESSES FOR THE PRODUCTION THEREOF | E INK CORPORATION (US) | 2009-01-08 | — | — | US | disclosed |
| US-7411720-B2 | Electrophoretic particles and processes for the production thereof | E INK CORPORATION (US) | 2008-08-12 | — | — | US | disclosed |
| US-20070128352-A1 | ELECTROPHORETIC PARTICLES AND PROCESSES FOR THE PRODUCTION THEREOF | E INK CORPORATION (US) | 2007-06-07 | — | — | US | disclosed |
| US-20050018273-A1 | ELECTROPHORETIC PARTICLES AND PROCESSES FOR THE PRODUCTION THEREOF | E INK CORPORATION (US) | 2005-01-27 | — | — | US | disclosed |
| US-6822782-B2 | SUSPENSION OF PIGMENT PARTICLES HAVING FROM ABOUT 1-15 PERCENT BY WEIGHT OF THE PIGMENT OF A POLYMER CHEMICALLY BONDED TO OR CROSSLINKED TO ENCAPSULATE THE PARTICLES; STABLE DISPERSIONS; DISPLAYS | E INK CORPORATION | 2004-11-23 | — | — | US | disclosed |
| EP-1393122-A1 | ELECTROPHORETIC PARTICLES | E Ink Corporation (US) | 2004-03-03 | — | — | EP | disclosed |
| US-20020185378-A1 | Electrophoretic particles and processes for the production thereof | E INK CORPORATION | 2002-12-12 | — | — | US | disclosed |
| WO-2002093246-A1 | ELECTROPHORETIC PARTICLES | E INK CORPORATION (US) | 2002-11-21 | — | — | WO | disclosed |