Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL159468 | 0.97 | — | — | |
| SCHEMBL9321573 | 0.94 | — | — | |
| SCHEMBL6895254 | 0.76 | TET2 (0.42) | — | |
| SCHEMBL11369765 | 0.75 | HTT (0.35) | — | |
| SCHEMBL350605 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL29135449 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL28229167 | 0.74 | LMNA (0.32) | — | |
| Hydrochloric Acid SCHEMBL6275324 | 0.74 | ACLY (0.52) | — | |
| SCHEMBL5527565 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL10884378 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106082466-B | A kind of large size multistage composite water purification control system and its process for purifying water | 徐州工程学院 | 2019-06-14 | — | — | CN | claimed |
| CN-106082466-A | A kind of large-scale multistage composite water purification control system and process for purifying water thereof | 徐州工程学院 | 2016-11-09 | — | — | CN | claimed |
| CN-103739786-B | Macromolecule quaternary salt anti-biotic material and preparation method thereof | 河南金誉包装科技股份有限公司 | 2016-08-17 | — | — | CN | claimed |
| JP-61280445-A | — | — | None | — | — | JP | disclosed |
| CN-106082466-B | A kind of large size multistage composite water purification control system and its process for purifying water | 徐州工程学院 | 2019-06-14 | — | — | CN | disclosed |
| CN-108689834-A | A kind of preparation method of the chloro- 2,2- dimethylpropionic acid chlorides of 3- | 江苏联化科技有限公司 | 2018-10-23 | — | — | CN | disclosed |
| CN-108689834-A | A kind of preparation method of the chloro- 2,2- dimethylpropionic acid chlorides of 3- | 江苏联化科技有限公司 | 2018-10-23 | — | — | CN | disclosed |
| CN-103833742-B | Pyrazolyl thiazolyl acrylonitrile compounds and application thereof | 沈阳中化农药化工研发有限公司 | 2016-12-21 | — | — | CN | disclosed |
| CN-103313976-B | sGC stimulators | 铁木医药有限公司 | 2016-11-23 | — | — | CN | disclosed |
| CN-106082466-A | A kind of large-scale multistage composite water purification control system and process for purifying water thereof | 徐州工程学院 | 2016-11-09 | — | — | CN | disclosed |
| CN-103739786-B | Macromolecule quaternary salt anti-biotic material and preparation method thereof | 河南金誉包装科技股份有限公司 | 2016-08-17 | — | — | CN | disclosed |
| EP-2459521-A1 | METHOD FOR THE PREPARATION OF W-AMINO-ALKANEAMIDES AND W-AMINO-ALKANETHIOAMIDES AS WELL AS INTERMEDIATES OF THIS METHOD | Sandoz AG (CH) | 2012-06-06 | — | — | EP | disclosed |
| WO-2012010651-A2 | METHOD FOR THE PREPARATION OF OMEGA-AMINO-ALKANEAMIDES AND OMEGA-AMINO-ALKANETHIOAMIDES AS WELL AS INTERMEDIATES OF THIS METHOD | SANDOZ AG (CH) | 2012-01-26 | — | — | WO | disclosed |
| US-20110117497-A1 | ACRYLATE DERIVATIVE, HALOESTER DERIVATIVE, POLYMER COMPOUND AND PHOTORESIST COMPOSITION | KURARAY CO., LTD. (JP) | 2011-05-19 | — | — | US | disclosed |
| WO-2011012319-A1 | METHOD FOR THE PREPARATION OF W-AMINO-ALKANEAMIDES AND W-AMINO-ALKANETHIOAMIDES AS WELL AS INTERMEDIATES OF THIS METHOD | SANDOZ AG (CH) | 2011-02-03 | — | — | WO | disclosed |
| US-5565457-A | FOR TREATMENT OF MYOCARDIAL ISCHEMIAS AND CEREBRAL VASCULAR DISORDERS | ADIR ET COMPAGNIE (FR) | 1996-10-15 | — | — | US | disclosed |
| JP-S61280445-A | PRODUCTION OF BETA-CHLOROPIVALIC ACID CHLORIDE | IHARA NIKKEI KAGAKU KOGYO KK | 1986-12-11 | — | — | JP | disclosed |
| US-4549994-A | INTERMEDIATES FOR MAKING CARBAMATE INSECTICIDE SYNERGISTS | BAYER AKTIENGESELLSCHAFT (DE) | 1985-10-29 | — | — | US | disclosed |
| US-4145414-A | ANTIVIRAL, IMMUNOSUPPRESSIVE, ANTILEUKEMIA | THE UPJOHN COMPANY (US) | 1979-03-20 | — | — | US | disclosed |
| US-4096324-A | ANTI-VIRAL, ANTILEUKEMIA | THE UPJOHN COMPANY (US) | 1978-06-20 | — | — | US | disclosed |