Hydrochloric Acid

Hydrochloric Acid

SCHEMBL456689

C=Cc1ccc(CN)cc1.Cl

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH3 known ✓ Q9Y5N1 1/20 0.48
CA2 known ✓ P00918 2/20 0.41
ALDH1A1 P00352 2/20 0.55
LOXL2 Q9Y4K0 7/20 0.46
ABAT P80404 1/20 0.44
F11 P03951 1/20 0.43
TSHR P16473 1/20 0.42
CA1 P00915 2/20 0.41
MAPT P10636 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
NOS3 P29474 1/20 0.39
NOS1 P29475 1/20 0.39
NOS2 P35228 1/20 0.39
F10 P00742 1/20 0.38
CA12 O43570 1/20 0.38
CA4 P22748 1/20 0.38
CA6 P23280 1/20 0.38
CA5A P35218 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL248455 0.97 ALDH1A1 (0.58) ALDH1A1HRH3LOXL2ABATF11
Iodide SCHEMBL28590159 0.95 ALDH1A1 (0.55) ALDH1A1HRH3LOXL2ABATF11
SCHEMBL27596146 0.91 HRH3 (0.64) ALDH1A1HRH3LOXL2ABATTSHR
Hydrochloric Acid SCHEMBL27664519 0.89 ALDH1A1 (0.44) ALDH1A1HRH3LOXL2ABATF11
Styrene SCHEMBL22466624 0.89 ALDH1A1 (0.61) ALDH1A1HRH3LOXL2ABATTSHR
Styrene SCHEMBL27722881 0.84 LOXL2 (0.61) ALDH1A1HRH3LOXL2TSHRMAPT
Trolamine SCHEMBL28661258 0.83 ALDH1A1 (0.38) ALDH1A1HRH3LOXL2ABATF11
Acetic Acid SCHEMBL11220768 0.82 KDM4E (0.51) ALDH1A1HRH3LOXL2ABATTSHR
Styrene SCHEMBL19118758 0.81 LOXL2 (0.64) ALDH1A1HRH3LOXL2TSHRTAAR1
Hydrochloric Acid SCHEMBL3630230 0.81 BLM (0.52) ALDH1A1LOXL2TAAR1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122051044-A Flexible composite capacitor electrode material and preparation method thereof 深圳市力容电子有限公司 2026-05-15 CN claimed
CN-119041203-A Antibacterial nylon fiber product and finishing method and application thereof 扬州纪元纺织有限公司 2024-11-29 CN claimed
CN-118930732-A High-temperature-resistant acidification corrosion inhibitor and system, and preparation method and application thereof 中国石油天然气股份有限公司 2024-11-12 CN claimed
CN-113563538-A Temperature-resistant and salt-resistant double-sensitive polymer oil-displacing agent and preparation method thereof 山东诺尔生物科技有限公司 2021-10-29 CN claimed
CN-108047378-B Hydrophobic association oil displacement polymer and preparation method thereof 山东诺尔生物科技有限公司 2021-03-02 CN claimed
CN-109293948-B Hydrogel and preparation method and application thereof 广东省医疗器械研究所 2021-01-26 CN claimed
CN-108047378-A A kind of hydrophobic association flooding polymers and preparation method thereof 山东诺尔生物科技有限公司 2018-05-18 CN claimed
CN-106008798-B The preparation method of micro- crosslinking net hydrophobic-associatcationic cationic polyacrylamide flocculant 河南正佳能源环保股份有限公司 2018-01-16 CN claimed
CN-101492515-B Acrylic amide modified graft copolymer, preparation method and application thereof UNIV CHENGDU TECHNOLOGY 2011-06-15 CN claimed
EP-2176304-A2 HIGH SOLIDS GLYOXALATED POLYACRYLAMIDE BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 2010-04-21 EP claimed
WO-2008157321-A2 HIGH SOLIDS GLYOXALATED POLYACRYLAMIDE BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 2008-12-24 WO claimed
EP-0265154-B1 IMPROVED METHOD FOR THE DETERMINATION OF BILIRUBIN AND AN ELEMENT USEFUL THEREIN EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-12-30 EP claimed
EP-0265154-A2 Improved method for the determination of bilirubin and an element useful therein EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1988-04-27 EP claimed
CN-122051044-A Flexible composite capacitor electrode material and preparation method thereof 深圳市力容电子有限公司 2026-05-15 CN disclosed
CN-122051044-A Flexible composite capacitor electrode material and preparation method thereof 深圳市力容电子有限公司 2026-05-15 CN disclosed
CN-119406259-A Single-molecule bipolar ion exchange membrane containing dissociation-promoting layer and preparation method thereof 孟广祯 2025-02-11 CN disclosed
EP-0103300-B2 ENCAPSULATION OF ELECTRONIC COMPONENTS WITH CALCIUM SILICATE-CONTAINING POLY(ARYLENE SULFIDE) COMPOSITIONS PHILLIPS PETROLEUM COMPANY (US) 1992-01-02 EP disclosed
EP-0249991-B1 COLOR FILTER ARRAYS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1991-08-28 EP disclosed
EP-0265154-A2 Improved method for the determination of bilirubin and an element useful therein EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1988-04-27 EP disclosed
EP-0249991-A2 Color filter arrays EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1987-12-23 EP disclosed