Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6445642 | 0.97 | ALDH1A1 (0.52) | ALDH1A1MAPT | |
| SCHEMBL35757 | 0.97 | ALDH1A1 (0.52) | ALDH1A1MAPT | |
| SCHEMBL8603798 | 0.94 | ALDH1A1 (0.50) | ALDH1A1MAPT | |
| SCHEMBL29504209 | 0.94 | ALDH1A1 (0.50) | ALDH1A1MAPT | |
| SCHEMBL17200965 | 0.94 | ALDH1A1 (0.50) | ALDH1A1MAPT | |
| Methane SCHEMBL23042745 | 0.94 | ALDH1A1 (0.50) | ALDH1A1MAPT | |
| Methane SCHEMBL4375438 | 0.94 | ALDH1A1 (0.50) | ALDH1A1MAPT | |
| Propane SCHEMBL3965748 | 0.92 | ALDH1A1 (0.50) | ALDH1A1MAPT | |
| Water SCHEMBL28932195 | 0.91 | ALDH1A1 (0.48) | ALDH1A1MAPT | |
| Propane SCHEMBL1529263 | 0.88 | ALDH1A1 (0.52) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4092126-A1 | A METHOD OF ENZYMATIC REDUCTION OF THE OXIDIZED NICOTINAMIDE ADENINE DINUCLEOTIDE AND CARBOXYLIC ACIDS | INSTYTUT KATALIZY I FIZYKOCHEMII POWIERZCHNI IM.JERZEGO HABERA POLSKIEJ AKADEMII NAUK (PL) | 2022-11-23 | — | — | EP | claimed |
| CN-118547216-A | Corrosion-resistant stainless steel band | 江苏贯森新材料科技有限公司 | 2024-08-27 | — | — | CN | disclosed |
| CN-117982458-A | Fused membrane-coated phenethyl caffeate/resveratrol nanoparticle and preparation method thereof | 重庆医科大学 | 2024-05-07 | — | — | CN | disclosed |
| US-11834553-B2 | Alkoxylation methods | NEKTAR THERAPEUTICS (US) | 2023-12-05 | — | — | US | disclosed |
| CN-117098550-A | Bioconjugate production process | 杨森制药公司 | 2023-11-21 | — | — | CN | disclosed |
| EP-4092126-A1 | A METHOD OF ENZYMATIC REDUCTION OF THE OXIDIZED NICOTINAMIDE ADENINE DINUCLEOTIDE AND CARBOXYLIC ACIDS | INSTYTUT KATALIZY I FIZYKOCHEMII POWIERZCHNI IM.JERZEGO HABERA POLSKIEJ AKADEMII NAUK (PL) | 2022-11-23 | — | — | EP | disclosed |
| US-20220169747-A1 | ANTI-HER2 BINDING MOLECULES | OLIVIA NEWTON-JOHN CANCER RESEARCH INSTITUTE (AU) | 2022-06-02 | — | — | US | disclosed |
| EP-2214716-B1 | HYDROXYAPATITE-TARGETING MULTIARM POLYMERS AND CONJUGATES MADE THEREFROM | NEKTAR THERAPEUTICS (US) | 2021-11-17 | — | — | EP | disclosed |
| US-20210024693-A1 | ALKOXYLATION METHODS | NEKTAR THERAPEUTICS | 2021-01-28 | — | — | US | disclosed |
| EP-2501413-B1 | ACID SALT FORMS OF POLYMER-DRUG CONJUGATES | NEKTAR THERAPEUTICS (US) | 2019-03-27 | — | — | EP | disclosed |
| US-20070031371-A1 | Method for Preparing Branched Functionalized Polymers Using Branched Polyol Cores | NEKTAR THERAPEUTICS AL, CORPORATION | 2007-02-08 | — | — | US | disclosed |
| WO-2007011802-A1 | METHOD FOR PREPARING BRANCHED FUNCTIONALIZED POLYMERS USING BRANCHED POLYOL CORES | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2007-01-25 | — | — | WO | disclosed |
| WO-2006001046-A1 | HYDROGELS OF HYALURONIC ACID AND ALPHA, BETA-POLYASPARTYLHYDRAZIDE AND THEIR BIOMEDICAL AND PHARMACEUTICAL USES | UNIVERSITA' DEGLI STUDI DI PALERMO (IT) | 2006-01-05 | — | — | WO | disclosed |
| US-20050224354-A1 | Separation process and dyes for use therewith | PERKINELMER LAS, INC. | 2005-10-13 | — | — | US | disclosed |
| EP-1556685-A2 | SEPARATION PROCESS AND DYES FOR USE THEREWITH | Perkinelmer Las, Inc. (US) | 2005-07-27 | — | — | EP | disclosed |
| CN-1188258-C | Process for high polymer synthesis to phenol compounds and the like and use thereof | SHOWA DENKO KK (JP) | 2005-02-09 | — | — | CN | disclosed |
| WO-2003092848-A2 | SEPARATION PROCESS AND DYES FOR USE THEREWITH | PERKINELMER, LAS, INC. (US) | 2003-11-13 | — | — | WO | disclosed |
| CN-1312150-A | Process for high polymer synthesis to phenol compounds and the like and use thereof | SHOWA DENKO KK (JP) | 2001-09-12 | — | — | CN | disclosed |
| CN-1217752-A | Method for producing polymer such as phenolic compound and the like and use thereof | SHOWA DENKO KK (JP) | 1999-05-26 | — | — | CN | disclosed |
| WO-1991011986-A1 | MOUTH WASHES AND DENTIFRICES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1991-08-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070031371-A1 | Method for Preparing Branched Functionalized Polymers Using Branched Polyol Cores | PARG, VIP, PHYKPL | ALDH1A1 4548/4885MAPT 2908/4885 |
| US-20210024693-A1 | ALKOXYLATION METHODS | ALK, ALKBH3, SLC10A1 | ALDH1A1 282/4885MAPT 1266/4885 |
| US-11834553-B2 | Alkoxylation methods | ALK, ALKBH3, SLC10A1 | ALDH1A1 282/4885MAPT 1266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.