Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 known ✓ | P50406 | 1/20 | 0.32 |
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7615277 | 0.77 | RET (0.35) | HTR6HTR2A | |
| Ethane SCHEMBL8628956 | 0.75 | RET (0.34) | HTR6HTR2A | |
| SCHEMBL18952179 | 0.74 | RET (0.36) | HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL8733929 | 0.74 | HTR6 (0.33) | HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL7945370 | 0.74 | SIGMAR1 (0.33) | HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL441680 | 0.72 | HTR2A (0.32) | HTR2A | |
| Hydrochloric Acid SCHEMBL4457343 | 0.72 | KDM4E (0.40) | HTR6HTR2A | |
| Ethane SCHEMBL8634247 | 0.71 | HTR2A (0.34) | HTR6HTR2A | |
| SCHEMBL550007 | 0.70 | HTR2A (0.38) | HTR6HTR2A | |
| SCHEMBL3685967 | 0.70 | HTR2A (0.38) | HTR6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6344577-B1 | COMPLEXING METAL, SILICON HYDROCARBYL COMPOUNDS AND CYCLOPENTADIENE | FINA TECHNOLOGY, INC. | 2002-02-05 | — | — | US | claimed |
| US-6117957-A | COORDINATION CATALYST | FINA TECHNOLOGY, INC. (US) | 2000-09-12 | — | — | US | claimed |
| US-5846896-A | Metallocene catalyst systems | FINA TECHNOLOGY, INC. (US) | 1998-12-08 | — | — | US | claimed |
| EP-0284708-B1 | Metallocene catalyst systems for olefin polymerization having a silicon hydrocarbyl bridge. | FINA TECHNOLOGY (US) | 1996-01-31 | — | — | EP | claimed |
| US-12071502-B2 | Method of making an ethylene-propylene copolymer | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2024-08-27 | — | — | US | disclosed |
| US-20240228677-A9 | METHOD OF MAKING AN ETHYLENE-PROPYLENE COPOLYMER | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2024-07-11 | — | — | US | disclosed |
| US-20240132635-A1 | METHOD OF MAKING AN ETHYLENE-PROPYLENE COPOLYMER | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2024-04-25 | — | — | US | disclosed |
| US-11926691-B2 | Method for making and using a supported zinc aluminum layered double hydroxide catalyst | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2024-03-12 | — | — | US | disclosed |
| US-20240034818-A1 | METHOD FOR MAKING AND USING A SUPPORTED ZINC ALUMINUM LAYERED DOUBLE HYDROXIDE CATALYST | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2024-02-01 | — | — | US | disclosed |
| US-11827734-B1 | Method of making a polyolefin | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2023-11-28 | — | — | US | disclosed |
| US-11746164-B1 | Method of making a polyolefin nanocomposite | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2023-09-05 | — | — | US | disclosed |
| US-7332456-B2 | Varying the melting points and molecular weights of polyolefins in a process of addition polymerization using metallocene catalyst which are chiral and stereorigid and include a bridge between the cyclopentadienyl groups | FINA TECHNOLOGY, INC. (US) | 2008-02-19 | — | — | US | disclosed |
| US-6649712-B2 | Changing the components and structure of the metallocene catalysts; melting point is controlled by the number of inversions in the xylene insoluble fraction of the polymer | FINA TECHNOLOGY, INC. | 2003-11-18 | — | — | US | disclosed |
| US-20020193537-A1 | Method for varying the melting points and molecular weights of polyolefins using metallocene catalyst systems | EWEN JOHN A (US) | 2002-12-19 | — | — | US | disclosed |
| US-20020111444-A1 | Alpha olefin polymer products and catalyst systems | EWEN JOHN A (US) | 2002-08-15 | — | — | US | disclosed |
| US-6344577-B1 | COMPLEXING METAL, SILICON HYDROCARBYL COMPOUNDS AND CYCLOPENTADIENE | FINA TECHNOLOGY, INC. | 2002-02-05 | — | — | US | disclosed |
| US-6117957-A | COORDINATION CATALYST | FINA TECHNOLOGY, INC. (US) | 2000-09-12 | — | — | US | disclosed |
| US-5846896-A | Metallocene catalyst systems | FINA TECHNOLOGY, INC. (US) | 1998-12-08 | — | — | US | disclosed |
| EP-0284708-B1 | Metallocene catalyst systems for olefin polymerization having a silicon hydrocarbyl bridge. | FINA TECHNOLOGY (US) | 1996-01-31 | — | — | EP | disclosed |
| EP-0284708-A1 | Metallocene catalyst systems for olefin polymerization having a silicon hydrocarbyl bridge. | FINA TECHNOLOGY, INC. (US) | 1988-10-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193537-A1 | Method for varying the melting points and molecular weights of polyolefins using metallocene catalyst systems | MRPS22, MRPS35, MCRS1 | HTR6 2528/4885HTR2A 1388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.