Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | ALKBH5 | Q6P6C2 | 7/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11499353 | 0.85 | ALDH1A1 (0.49) | ALDH1A1MAPTKMT2AKDM4EGAA | |
| SCHEMBL395368 | 0.80 | ALDH1A1 (0.66) | ALDH1A1MAPTKMT2AKDM4EGAA | |
| SCHEMBL486125 | 0.76 | MAPT (0.73) | ALDH1A1MAPTKMT2AKDM4EGAA | |
| SCHEMBL11651771 | 0.75 | ALDH1A1 (0.59) | ALDH1A1MAPTKMT2AKDM4EGAA | |
| SCHEMBL8418696 | 0.75 | MAPT (0.59) | ALDH1A1MAPTKMT2AKDM4EGAA | |
| SCHEMBL7247608 | 0.75 | MAPT (0.63) | ALDH1A1MAPTKMT2AKDM4EGAA | |
| SCHEMBL699253 | 0.74 | MAPT (0.57) | ALDH1A1MAPTKMT2AKDM4EGAA | |
| SCHEMBL11652982 | 0.74 | MAPT (0.57) | ALDH1A1MAPTKMT2AKDM4EGAA | |
| SCHEMBL697599 | 0.74 | MAPT (0.57) | ALDH1A1MAPTKMT2AKDM4EGAA | |
| SCHEMBL7246252 | 0.74 | ALDH1A1 (0.61) | ALDH1A1MAPTKMT2AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230414484-A1 | GRANULATED HAIR DYE COMPOSITION | WELLA GERMANY GMBH (DE) | 2023-12-28 | — | — | US | disclosed |
| EP-3512488-B1 | HAIR COLOR COMPOSITIONS COMPRISING STABLE VIOLET-BLUE TO BLUE IMIDAZOLIUM DYES | WELLA OPERATIONS US LLC (US) | 2023-12-06 | — | — | EP | disclosed |
| EP-3512604-B1 | STABLE YELLOW IMIDAZOLIUM COMPOUNDS AND METHODS FOR THEIR USE | WELLA OPERATIONS US LLC (US) | 2023-05-31 | — | — | EP | disclosed |
| US-11142498-B2 | Keratin dyeing compounds, compositions containing them, and method and use thereof | WELLA OPERATIONS US, LLC (US) | 2021-10-12 | — | — | US | disclosed |
| US-20200247749-A1 | KERATIN DYEING COMPOUNDS, COMPOSITIONS CONTAINING THEM, AND METHOD AND USE THEREOF | WELLA OPERATIONS US, LLC | 2020-08-06 | — | — | US | disclosed |
| EP-3512604-A1 | STABLE YELLOW IMIDAZOLIUM COMPOUNDS AND METHODS FOR THEIR USE | Noxell Corporation (US) | 2019-07-24 | — | — | EP | disclosed |
| US-10093667-B1 | Coumarinyl-thiazole-sulfonyl conjugate and preparation thereof | COMSATS INSTITUTE OF INFORMATION TECHNOLOGY (PK) | 2018-10-09 | — | — | US | disclosed |
| US-10093807-B2 | Stable yellow imidazolium compounds | NOXELL CORPORATION (US) | 2018-10-09 | — | — | US | disclosed |
| US-20180244924-A1 | Cationic Direct Dyes | BASF SE (DE) | 2018-08-30 | — | — | US | disclosed |
| EP-2677993-B1 | OXIDATIVE DYEING COMPOSITIONS COMPRISING AN 1-HEXYL/HEPTYL-4,5-DIAMINOPYRAZOLE AND A M-AMINOPHENOL AND DERIVATIVES THEREOF | NOXELL CORP (US) | 2018-08-22 | — | — | EP | disclosed |
| US-20120210522-A1 | Oxidative Dyeing Compositions Comprising an 1-Hexyl/Heptyl-4,5-diaminopyrazole and a Naphthalen-1-ol and Derivatives Thereof | WELLA OPERATIONS US, LLC | 2012-08-23 | — | — | US | disclosed |
| US-20120210520-A1 | Oxidative Dyeing Compositions Comprising an 1-Hexyl/Heptyl-4,5-diaminopyrazole and a m-Aminophenol and Derivatives Thereof | WELLA OPERATIONS US, LLC | 2012-08-23 | — | — | US | disclosed |
| US-20120210524-A1 | Oxidative Dyeing Compositions Comprising an 1-Hexyl/Heptyl-4,5-diaminopyrazole and a Benzene-1,3-diamine and Derivatives Thereof | WELLA OPERATIONS US, LLC | 2012-08-23 | — | — | US | disclosed |
| US-20120210526-A1 | Oxidative Dyeing Compositions Comprising an 1-Hexyl/Heptyl-4,5-diaminopyrazole and a Pyridine and Derivatives Thereof | WELLA OPERATIONS US, LLC | 2012-08-23 | — | — | US | disclosed |
| US-20120210521-A1 | Oxidative Dyeing Compositions Comprising an 1-Hexyl/Heptyl-4,5-diaminopyrazole and a Benzo[1,3]dioxol-5-ylamine and Derivatives Thereof | WELLA OPERATIONS US, LLC | 2012-08-23 | — | — | US | disclosed |
| US-8106086-B2 | Indoledione derivative | MSD K.K. (JP) | 2012-01-31 | — | — | US | disclosed |
| US-20100056597-A1 | INDOLEDIONE DERIVATIVE | MSD K.K. (JP) | 2010-03-04 | — | — | US | disclosed |
| EP-2145884-A1 | INDOLEDIONE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-01-20 | — | — | EP | disclosed |
| US-7513943-B2 | Yellow dye compound and ink composition comprising the same | EVERLIGHT USA, INC. (US) | 2009-04-07 | — | — | US | disclosed |
| US-20090056586-A1 | Yellow dye compound and ink composition comprising the same | EVERLIGHT USA, INC. (US) | 2009-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120210521-A1 | Oxidative Dyeing Compositions Comprising an 1-Hexyl/Heptyl-4,5-diaminopyrazole and a Benzo[1,3]dioxol-5-ylamine and Derivatives Thereof | KRT18, HK1, AOX1 | ALDH1A1 161/4885MAPT 1041/4885KMT2A 2402/4885 |
| US-20100056597-A1 | INDOLEDIONE DERIVATIVE | LIPE, IDO1, ADRA1A | ALDH1A1 303/4885MAPT 2831/4885KMT2A 776/4885 |
| US-20090056586-A1 | Yellow dye compound and ink composition comprising the same | RB1, TYR, IK | ALDH1A1 551/4885MAPT 565/4885KMT2A 1041/4885 |
| US-20120210520-A1 | Oxidative Dyeing Compositions Comprising an 1-Hexyl/Heptyl-4,5-diaminopyrazole and a m-Aminophenol and Derivatives Thereof | KRT18, AOC1, S100P | ALDH1A1 153/4885MAPT 753/4885KMT2A 2571/4885 |
| US-20120210526-A1 | Oxidative Dyeing Compositions Comprising an 1-Hexyl/Heptyl-4,5-diaminopyrazole and a Pyridine and Derivatives Thereof | KRT18, NOX4, AOC1 | ALDH1A1 169/4885MAPT 1063/4885KMT2A 3270/4885 |
| US-20120210522-A1 | Oxidative Dyeing Compositions Comprising an 1-Hexyl/Heptyl-4,5-diaminopyrazole and a Naphthalen-1-ol and Derivatives Thereof | AOC1, NOX1, AOX1 | ALDH1A1 55/4885MAPT 3316/4885KMT2A 4328/4885 |
| US-20120210524-A1 | Oxidative Dyeing Compositions Comprising an 1-Hexyl/Heptyl-4,5-diaminopyrazole and a Benzene-1,3-diamine and Derivatives Thereof | KRT18, AOC1, NOX4 | ALDH1A1 55/4885MAPT 1709/4885KMT2A 3271/4885 |
| US-20230414484-A1 | GRANULATED HAIR DYE COMPOSITION | SHH, CUTA, DSG1 | ALDH1A1 2333/4885MAPT 654/4885KMT2A 3273/4885 |
| US-11142498-B2 | Keratin dyeing compounds, compositions containing them, and method and use thereof | KRT18, MARK4, MKI67 | ALDH1A1 334/4885MAPT 761/4885KMT2A 1748/4885 |
| US-10093807-B2 | Stable yellow imidazolium compounds | IK, NDUFV1, NDUFV2 | ALDH1A1 1345/4885MAPT 316/4885KMT2A 1974/4885 |
| US-20180244924-A1 | Cationic Direct Dyes | H1-0, TPH1, H1-2 | ALDH1A1 39/4885MAPT 3520/4885KMT2A 994/4885 |
| US-20200247749-A1 | KERATIN DYEING COMPOUNDS, COMPOSITIONS CONTAINING THEM, AND METHOD AND USE THEREOF | KRT18, PRKDC, MKI67 | ALDH1A1 385/4885MAPT 861/4885KMT2A 1807/4885 |
| US-10093667-B1 | Coumarinyl-thiazole-sulfonyl conjugate and preparation thereof | OPRK1, OPRL1, OGFR | ALDH1A1 63/4885MAPT 1461/4885KMT2A 3625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.