Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL342560 | 0.79 | KDM4E (0.47) | PDE4BPDE4APDE4CPDE4DKDM4E | |
| SCHEMBL571774 | 0.77 | KDM4E (0.32) | PDE4BPDE4APDE4CPDE4DKDM4E | |
| SCHEMBL28362662 | 0.76 | PDE4B (0.47) | PDE4BPDE4APDE4CPDE4DKDM4E | |
| SCHEMBL6348670 | 0.72 | PDE4B (0.48) | PDE4BPDE4APDE4CPDE4DKDM4E | |
| SCHEMBL571737 | 0.72 | KDM4E (0.56) | PDE4BPDE4APDE4CPDE4DKDM4E | |
| SCHEMBL16132605 | 0.68 | PDE4B (0.47) | PDE4BPDE4APDE4CPDE4DKDM4E | |
| SCHEMBL342126 | 0.67 | KDM4E (0.45) | PDE4DKDM4ECYP3A4ALOX12TDP1 | |
| SCHEMBL16132598 | 0.66 | PDE4B (0.46) | PDE4BPDE4APDE4CPDE4DKDM4E | |
| SCHEMBL4701737 | 0.66 | PDE4B (0.61) | PDE4BPDE4APDE4CPDE4DKDM4E | |
| SCHEMBL7323219 | 0.65 | GABRA1 (0.39) | KDM4EGAAHTTMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167088-A1 | 1-PYRAZINYLPYRAZOLYL-3-OXYALKYL ACIDS AND THEIR DERIVATIVES, AND THEIR USE FOR CONTROL OF UNDESIRED PLANT GROWTH | BAYER AKTIENGESELLSCHAFT (DE) | 2023-06-01 | — | — | US | disclosed |
| US-20230159472-A1 | SUBSTITUTED ISOPHTHALIC ACID DIAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-05-25 | — | — | US | disclosed |
| US-20230126893-A1 | [(1,4,5-TRISUBSTITUTED-1H-PYRAZOL-3-YL)SULFANYL]ACETIC ACID DERIVATIVES, SALTS THEREOF, AND USE THEREOF AS ACTIVE HERBICIDAL INGREDIENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-04-27 | — | — | US | disclosed |
| US-10301257-B2 | Use of acylsulfonamides for improving plant yield | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2019-05-28 | — | — | US | disclosed |
| US-9848602-B2 | Use of prothioconazole to induce host defence responses | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-12-26 | — | — | US | disclosed |
| US-9661848-B2 | Substituted 4-cyan-3-(pyridyl)-4-phenylbutanoates, method for the production thereof and uses as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2017-05-30 | — | — | US | disclosed |
| US-9609863-B2 | Herbicide/safener compositions containing N-(tetrazol-5-yl) aryl carboxylic acid amides and N-(triazol-5-yl) aryl carboxylic acid amides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-04-04 | — | — | US | disclosed |
| US-9375002-B2 | 5-aminopyrimidine derivatives and use thereof for combating undesired plant growth | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-06-28 | — | — | US | disclosed |
| US-9332759-B2 | Herbicide safener compositions | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-05-10 | — | — | US | disclosed |
| US-20150373975-A1 | USE OF PROTHIOCONAZOLE TO INDUCE HOST DEFENCE RESPONSES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2015-12-31 | — | — | US | disclosed |
| US-20070015661-A1 | Herbicide/safener combination | BAYER CROPSCIENCE GMBH (DE) | 2007-01-18 | — | — | US | disclosed |
| US-20070015662-A1 | Herbicide/safener combination | BAYER CROPSCIENCE GMBH (DE) | 2007-01-18 | — | — | US | disclosed |
| US-20060276342-A1 | Herbicidal compositions | BAYER CROPSCIENCE GMBH (DE) | 2006-12-07 | — | — | US | disclosed |
| US-20060240984-A1 | Herbicidal compositions | PALLETT KEN | 2006-10-26 | — | — | US | disclosed |
| US-7101827-B2 | Herbicides comprising benzoylcyclohexanediones and safeners | AVENTIS CROPSCIENCE GMBH (DE) | 2006-09-05 | — | — | US | disclosed |
| US-20050233906-A1 | Oil suspension concentrate | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2005-10-20 | — | — | US | disclosed |
| US-20050070437-A1 | Herbicide combinations comprising specific sulfonamides | BAYER CROPSCIENCE GMBH (DE) | 2005-03-31 | — | — | US | disclosed |
| US-6864217-B2 | Herbicidal compositions with substituted phenylsulfonylureas for controlling weeds in rice | HOECHST SCHERING AGREVO GMBH (DE) | 2005-03-08 | — | — | US | disclosed |
| US-20040224848-A1 | Herbicides comprising benzoylcyclohexanediones and safeners | AVENTIS CROPSCIENCE GMBH (DE) | 2004-11-11 | — | — | US | disclosed |
| US-20040157739-A1 | Amino-1,3,5-triazines N-substituted with chiral bicyclic radicals, process for their preparation, compositions thereof, and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060240984-A1 | Herbicidal compositions | DDT, GLRX3, GPX1 | PDE4B 2620/4885PDE4A 3080/4885PDE4C 2783/4885 |
| US-20050070437-A1 | Herbicide combinations comprising specific sulfonamides | DDT, B2M, MTX2 | PDE4B 2791/4885PDE4A 2404/4885PDE4C 2785/4885 |
| US-20070015662-A1 | Herbicide/safener combination | CYP2W1, CBR3, DDT | PDE4B 2585/4885PDE4A 2351/4885PDE4C 3264/4885 |
| US-20040157739-A1 | Amino-1,3,5-triazines N-substituted with chiral bicyclic radicals, process for their preparation, compositions thereof, and their use as herbicides and plant growth regulators | CYP4Z1, IL4I1, BCAT1 | PDE4B 2772/4885PDE4A 2775/4885PDE4C 2297/4885 |
| US-20070015661-A1 | Herbicide/safener combination | CBR3, CBR1, GSR | PDE4B 2764/4885PDE4A 2873/4885PDE4C 3768/4885 |
| US-20230167088-A1 | 1-PYRAZINYLPYRAZOLYL-3-OXYALKYL ACIDS AND THEIR DERIVATIVES, AND THEIR USE FOR CONTROL OF UNDESIRED PLANT GROWTH | AGPS, CBR3, HPD | PDE4B 2131/4885PDE4A 1539/4885PDE4C 1824/4885 |
| US-20230126893-A1 | [(1,4,5-TRISUBSTITUTED-1H-PYRAZOL-3-YL)SULFANYL]ACETIC ACID DERIVATIVES, SALTS THEREOF, AND USE THEREOF AS ACTIVE HERBICIDAL INGREDIENTS | SYMPK, ALDH7A1, AADAC | PDE4B 1435/4885PDE4A 1864/4885PDE4C 1512/4885 |
| US-10301257-B2 | Use of acylsulfonamides for improving plant yield | ARSA, ACSS2, NAT1 | PDE4B 1834/4885PDE4A 1736/4885PDE4C 2133/4885 |
| US-20150373975-A1 | USE OF PROTHIOCONAZOLE TO INDUCE HOST DEFENCE RESPONSES | SLC11A2, ERG28, CYTH3 | PDE4B 1781/4885PDE4A 2553/4885PDE4C 2509/4885 |
| US-20230159472-A1 | SUBSTITUTED ISOPHTHALIC ACID DIAMIDES | DDT, IDH2, DAO | PDE4B 2799/4885PDE4A 3054/4885PDE4C 2620/4885 |
| US-20040224848-A1 | Herbicides comprising benzoylcyclohexanediones and safeners | DDT, HPD, HDHD5 | PDE4B 2491/4885PDE4A 1809/4885PDE4C 2166/4885 |
| US-20050233906-A1 | Oil suspension concentrate | TST, PFAS, STS | PDE4B 2300/4885PDE4A 3527/4885PDE4C 3252/4885 |
| US-20060276342-A1 | Herbicidal compositions | DDT, HDHD5, DGAT2 | PDE4B 345/4885PDE4A 595/4885PDE4C 715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.