Hydrochloric Acid

Hydrochloric Acid

SCHEMBL58713

CC(CCCN(C)C)N=C=N.Cl

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HTR2A known ✓ P28223 1/20 0.33
HRH1 known ✓ P35367 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
DNM1 Q05193 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28055620 0.98 HTR2A (0.32) HTR2AHRH1ALDH1A1TSHRDNM1
Hydrochloric Acid SCHEMBL28055592 0.98 HTR2A (0.32) HTR2AHRH1ALDH1A1TSHRDNM1
SCHEMBL551460 0.98 ALDH1A1 (0.35) HTR2AHRH1ALDH1A1TSHRDNM1
SCHEMBL27759471 0.96 HTR2A (0.33) HTR2AHRH1ALDH1A1TSHRCYP1A2
Water SCHEMBL27976893 0.96 HTR2A (0.33) HTR2AHRH1ALDH1A1TSHRCYP1A2
Water SCHEMBL28125507 0.96 HTR2A (0.33) HTR2AHRH1ALDH1A1TSHRCYP1A2
Carbimide SCHEMBL27427109 0.96 HTR2A (0.33) HTR2AHRH1ALDH1A1TSHRCYP1A2
Iodomethane SCHEMBL3061558 0.94 HTR2A (0.32) HTR2AHRH1ALDH1A1TSHR
Alcohol SCHEMBL28135656 0.93 DNM1 (0.32) HTR2AHRH1DNM1CYP1A2CYP2D6
Methylene Chloride SCHEMBL27550128 0.92 HTR2A (0.32) HTR2AHRH1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3969 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116790059-B Preparation method of antibacterial plastic-wood material and antibacterial floor 美新科技股份有限公司 2024-11-19 CN claimed
US-12050225-B2 Ultra-fast and highly-sensitive chemiluminescent immunoassay method for detecting thyroid stimulating hormone SHANDONG UNIVERSITY (CN) 2024-07-30 US claimed
US-20240230685-A9 ULTRA-FAST AND HIGHLY-SENSITIVE CHEMILUMINESCENT IMMUNOASSAY METHOD FOR DETECTING THYROID STIMULATING HORMONE UNIV SHANDONG (CN) 2024-07-11 US claimed
US-20240133902-A1 ULTRA-FAST AND HIGHLY-SENSITIVE CHEMILUMINESCENT IMMUNOASSAY METHOD FOR DETECTING THYROID STIMULATING HORMONE SHANDONG UNIVERSITY (CN) 2024-04-25 US claimed
CN-114350755-B High-sensitivity microRNA fluorescent in-situ hybridization quantitative labeling probe based on semiconductor polymer dots and preparation method thereof 吉林大学 2024-04-09 CN claimed
CN-111693706-B Tylosin and tilmicosin rapid fluorescence detection reagent and application 江苏大学 2024-02-13 CN claimed
CN-117257990-A Brain-targeted nano-particles loaded with bighead atractylodes rhizome lactone, and preparation method and application thereof 湖南师范大学 2023-12-22 CN claimed
CN-116949045-A Bow bacteria and campylobacter differentiation detection method based on dual-channel fluorescent biosensor 青岛中创汇科生物科技有限公司 2023-10-27 CN claimed
CN-116920163-A Multifunctional hydrogel precursor patch and preparation method thereof 沈阳药科大学 2023-10-24 CN claimed
CN-116790059-A Preparation method of antibacterial plastic-wood material and antibacterial floor 美新科技股份有限公司 2023-09-22 CN claimed
CN-1411445-A Method for preparing 3-hydroxypicolinic acid derivatives AVENTIS CROPSCIENCE SA (FR) 2003-04-16 CN claimed
CN-1400968-A Method for preparing alpha sulfonyl hydroxamic acid derivatives AMERICAN CYANAMID CO (US) 2003-03-05 CN claimed
CN-1397557-A NOvel octahydro-2H-pyridino-[1,2-a] pyrazine compound, its prepn. process and medicinal compound contg. them SAVOIREN LAB (FR) 2003-02-19 CN claimed
EP-0556216-B1 PHOSPHORIC ACID ESTERS AND THEIR USE IN THE PREPARATION OF BIOCOMPATIBLE SURFACES BIOCOMPATIBLES LTD (GB) 1997-06-04 EP claimed
US-5599587-A Phosphoric acid esters and their use in the preparation of biocompatible surfaces BIOCOMPATIBLES LIMITED (GB) 1997-02-04 US claimed
US-5496522-A Biosensor and chemical sensor probes for calcium and other metal ions MARTIN MARIETTA ENERGY SYSTEMS, INC. (US) 1996-03-05 US claimed
CN-1094725-A Process for preparing taxanes with side chain and intermediates thereof BRISTOL MYERS SQIBB COMPANY (US) 1994-11-09 CN claimed
EP-0061760-B1 A METHOD FOR PREPARING A MONONUCLEOTIDE-3'-PHOSPHODIESTER-BASED SUBSTRATE Baker Instruments Corporation (US) 1988-03-02 EP claimed
US-4529796-A Method for making chromogenic and/or fluorogenic substrates for use in monitoring catalytic or enzymatic activity BAKER INSTRUMENTS CORPORATION (US) 1985-07-16 US claimed
EP-0061760-A1 A method for preparing a mononucleotide-3'-phosphodiester-based substrate Baker Instruments Corporation (US) 1982-10-06 EP claimed