Hydrochloric Acid

Hydrochloric Acid

SCHEMBL637396

CCCCCCCCC(C)C(C)(C)N.Cl

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 known ✓ P35372 1/20 0.46
SPHK1 Q9NYA1 2/20 0.43
DNM1 Q05193 4/20 0.39
LMNA P02545 2/20 0.38
TP53 P04637 2/20 0.38
CYP2D6 P10635 2/20 0.36
ADH1B P00325 1/20 0.36
ADH1C P00326 1/20 0.36
ADH1A P07327 1/20 0.36
ADH4 P08319 1/20 0.36
ADH7 P40394 1/20 0.36
PLA2G1B P04054 1/20 0.36
PLA2G2A P14555 1/20 0.36
GMNN O75496 1/20 0.36
POLB P06746 1/20 0.36
THPO P40225 1/20 0.36
MTOR P42345 1/20 0.36
BLM P54132 1/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP1A2 P05177 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL136267 1.00 OPRM1 (0.46) OPRM1SPHK1DNM1LMNATP53
Hydrochloric Acid SCHEMBL15823526 1.00 OPRM1 (0.46) OPRM1SPHK1DNM1LMNATP53
Hydrochloric Acid SCHEMBL3101949 1.00 OPRM1 (0.46) OPRM1SPHK1DNM1LMNATP53
Hydrochloric Acid SCHEMBL3104729 1.00 OPRM1 (0.46) OPRM1SPHK1DNM1LMNATP53
Hydrochloric Acid SCHEMBL634994 1.00 OPRM1 (0.46) OPRM1SPHK1DNM1LMNATP53
Hydrochloric Acid SCHEMBL9420650 1.00 OPRM1 (0.46) OPRM1SPHK1DNM1LMNATP53
Hydrochloric Acid SCHEMBL1254112 1.00 OPRM1 (0.46) OPRM1SPHK1DNM1LMNATP53
Hydrochloric Acid SCHEMBL5138752 1.00 OPRM1 (0.46) OPRM1SPHK1DNM1LMNATP53
Hydrochloric Acid SCHEMBL534401 1.00 OPRM1 (0.46) OPRM1SPHK1DNM1LMNATP53
Hydrochloric Acid SCHEMBL8357940 1.00 OPRM1 (0.46) OPRM1SPHK1DNM1LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 253 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-63230620-A None JP disclosed
WO-2025125232-A1 METHOD FOR THE EMULSION RADICAL POLYMERISATION OF A MONOMER MIXTURE OF 1,3-BUTADIENE AND (METH)ACRYLATE COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2025-06-19 WO disclosed
WO-2025125233-A1 STATISTICAL ELASTOMER COPOLYMER OF 1,3-BUTADIENE AND OF A (METH)ACRYLATE COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2025-06-19 WO disclosed
US-20230014137-A1 COMPOUND HAVING LYSOPHOSPHATIDIC ACID RECEPTOR AGONIST ACTIVITY AND PHARMACEUTICAL USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2023-01-19 US disclosed
EP-4066895-A1 COMPOUND HAVING LYSOPHOSPHATIDIC ACID RECEPTOR AGONISTIC ACTIVITY AND PHARMACEUTICAL USE OF SAID COMPOUND ONO Pharmaceutical Co., Ltd. (JP) 2022-10-05 EP disclosed
CN-110007564-B Multi-coat infrared radiation sensitive positive working lithographic printing plate precursor and method of forming image 浙江康尔达新材料股份有限公司 2022-05-20 CN disclosed
CN-109476178-B Rubber composition comprising a diene elastomer containing carbonate functions 米其林集团总公司 2021-08-10 CN disclosed
WO-2021107125-A1 COMPOUND HAVING LYSOPHOSPHATIDIC ACID RECEPTOR AGONISTIC ACTIVITY AND PHARMACEUTICAL USE OF SAID COMPOUND 小野薬品工業株式会社 2021-06-03 WO disclosed
US-20210147403-A1 SUBSTITUTED PYRROLIDINES AS FACTOR XIA INHIBITORS FOR THE TREATMENT THROMBOEMBOLIC DISEASES ONO PHARMACEUTICAL CO., LTD. (JP) 2021-05-20 US disclosed
US-10920046-B2 Rubber composition including a diene elastomer comprising carbonate functional groups COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2021-02-16 US disclosed
US-5034404-A Nitroguanidines as insecticides TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-07-23 US disclosed
EP-0392560-A2 Diaminoethylene compounds Takeda Chemical Industries, Ltd. (JP) 1990-10-17 EP disclosed
EP-0376279-A2 Guanidine derivatives, their production and insecticides Takeda Chemical Industries, Ltd. (JP) 1990-07-04 EP disclosed
EP-0366085-A2 Tetrahydropyrimidines, their production and use Takeda Chemical Industries, Ltd. (JP) 1990-05-02 EP disclosed
US-4848465-A Use of alkali metal silicate foam with a chemical blowing agent MOBIL OIL CORP. (US) 1989-07-18 US disclosed
EP-0102062-B1 1,3-DITHIANES, THEIR PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 1988-11-23 EP disclosed
JP-S63230620-A HAIR RINSE COMPOSITION ASAHI DENKA KOGYO KK 1988-09-27 JP disclosed
US-4676318-A Method of reducing permeability in subterranean formation by use of alkali metal silicate foam EXXON PRODUCTION RESEARCH COMPANY (US) 1987-06-30 US disclosed
US-4640929-A Insecticidally, acaricidally, and nematocidally 2-amino-1,3-dithiane derivatives and pesticidal compositions therefor TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1987-02-03 US disclosed
EP-0102062-A2 1,3-Dithianes, their production and use Takeda Chemical Industries, Ltd. (JP) 1984-03-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210147403-A1 SUBSTITUTED PYRROLIDINES AS FACTOR XIA INHIBITORS FOR THE TREATMENT THROMBOEMBOLIC DISEASES F11, F10, F9 OPRM1 2842/4885SPHK1 2677/4885DNM1 3462/4885
US-20230014137-A1 COMPOUND HAVING LYSOPHOSPHATIDIC ACID RECEPTOR AGONIST ACTIVITY AND PHARMACEUTICAL USE THEREOF LPAR1, LPAR4, LPAR2 OPRM1 1735/4885SPHK1 241/4885DNM1 2867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.