Hydrochloric Acid

Hydrochloric Acid

SCHEMBL6832625

CCCCCCCCC(N)(CCCCCCCC)C(C)O.Cl

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FDPS P14324 9/20 0.44
SMPD1 P17405 4/20 0.44
SPHK1 Q9NYA1 1/20 0.42
GGPS1 O95749 5/20 0.38
DNM1 Q05193 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6558334 0.98 FDPS (0.45) FDPSSMPD1SPHK1GGPS1
SCHEMBL7752435 0.89 FDPS (0.41) FDPSSMPD1SPHK1
Hydrochloric Acid SCHEMBL5604440 0.84 FDPS (0.45) FDPSSMPD1SPHK1GGPS1DNM1
Hydrochloric Acid SCHEMBL4443834 0.83 FDPS (0.44) FDPSSMPD1SPHK1GGPS1DNM1
Hydrochloric Acid SCHEMBL16468331 0.83 FDPS (0.44) FDPSSMPD1SPHK1GGPS1DNM1
SCHEMBL4448029 0.82 FDPS (0.47) FDPSSMPD1SPHK1GGPS1
SCHEMBL3676595 0.80 FDPS (0.45) FDPSSMPD1SPHK1GGPS1
SCHEMBL123833 0.80 FDPS (0.45) FDPSSMPD1SPHK1GGPS1
Bromide SCHEMBL28893997 0.80 FDPS (0.45) FDPSSMPD1SPHK1GGPS1DNM1
SCHEMBL3677155 0.80 FDPS (0.45) FDPSSMPD1SPHK1GGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040071653-A1 Antimicrobial ternary surfactant blend comprising cationic, anionic, and bridging surfactants, and methods of preparing same STEPAN COMPANY 2004-04-15 US disclosed
EP-1324821-A2 EMULSION COMPRISING A BLEND OF CATIONIC, ANIONIC AND BRIDGING SURFACTANS, OIL AND WATER STEPAN COMPANY (US) 2003-07-09 EP disclosed
EP-1320354-A2 SHAMPOO AND BODY WASH COMPOSITION STEPAN COMPANY (US) 2003-06-25 EP disclosed
EP-1318720-A2 ANTIMICROBIAL TERNARY SURFACTANT BLEND COMPRISING CATIONIC, ANIONIC, AND BRIDGING SURFACTANTS, AND METHODS OF PREPARING SAME STEPAN COMPANY (US) 2003-06-18 EP disclosed
US-6528070-B1 Emulsification system comprising a mixture of at least one cationic surfactant, at least one anionic surfactant, at least one \"bridging surfactant\", an oil and water, along with methods for preparing such emulsions. Synergistic mixtures of STEPAN COMPANY 2003-03-04 US disclosed
EP-1257350-A1 TERNARY SURFACTANT BLENDS COMPRISING CATIONIC, ANIONIC, AND BRIDGING SURFACTANTS AND METHODS OF PREPARING SAME STEPAN COMPANY (US) 2002-11-20 EP disclosed
WO-2002022083-A2 EMULSION COMPRISING A BLEND OF CATIONIC, ANIONIC AND BRIDGING SURFACTANTS, OIL AND WATER STEPAN COMPANY (US) 2002-03-21 WO disclosed
WO-2002021916-A2 ANTIMICROBIAL TERNARY SURFACTANT BLEND COMPRISING CATIONIC, ANIONIC, AND BRIDGING SURFACTANTS, AND METHODS OF PREPARING SAME STEPAN COMPANY (US) 2002-03-21 WO disclosed
WO-2002022105-A2 SHAMPOO AND BODY WASH COMPOSITION STEPAN COMPANY (US) 2002-03-21 WO disclosed
US-6306805-B1 Shampoo and body wash composition comprising ternary surfactant blends of cationic, anionic, and bridging surfactants and methods of preparing same STEPAN COMPANY 2001-10-23 US disclosed
WO-2001019507-A1 TERNARY SURFACTANT BLENDS COMPRISING CATIONIC, ANIONIC, AND BRIDGING SURFACTANTS AND METHODS OF PREPARING SAME STEPAN COMPANY (US) 2001-03-22 WO disclosed
US-5472455-A Water soluble complexes for removing oily stains from fabrics COLGATE PALMOLIVE CO. (US) 1995-12-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040071653-A1 Antimicrobial ternary surfactant blend comprising cationic, anionic, and bridging surfactants, and methods of preparing same ARG1, SEPTIN7, NRDC FDPS 2218/4885SMPD1 276/4885SPHK1 2934/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.