Hydrochloric Acid

Hydrochloric Acid

SCHEMBL7013379

C=CC(Cc1ccccc1)N(C)C.Cl

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 known ✓ P23975 3/20 0.43
SLC6A4 known ✓ P31645 2/20 0.43
SLC6A3 known ✓ Q01959 2/20 0.43
ADRA2B known ✓ P18089 2/20 0.43
ADRA2C known ✓ P18825 2/20 0.43
ADRA1A known ✓ P35348 2/20 0.43
OPRK1 known ✓ P41145 2/20 0.43
HTR2A known ✓ P28223 1/20 0.43
KCNH2 known ✓ Q12809 1/20 0.43
MAOA known ✓ P21397 3/20 0.41
MAOB known ✓ P27338 3/20 0.41
SIGMAR1 known ✓ Q99720 4/20 0.41
ADRA2A known ✓ P08913 1/20 0.39
ALDH1A1 P00352 2/20 0.44
MAPT P10636 1/20 0.44
MAPK1 P28482 1/20 0.41
KDM4E B2RXH2 1/20 0.41
TAAR1 Q96RJ0 2/20 0.41
CYP2A6 P11509 1/20 0.41
ADORA2A P29274 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL28021133 0.98 ALDH1A1 (0.43) ALDH1A1MAPTSLC6A2SLC6A4SLC6A3
SCHEMBL995542 0.98 SLC6A2 (0.44) ALDH1A1MAPTSLC6A2SLC6A4SLC6A3
Bromide SCHEMBL16897881 0.96 SLC6A2 (0.43) ALDH1A1MAPTSLC6A2SLC6A4SLC6A3
Hydrochloric Acid SCHEMBL28021476 0.84 TSHR (0.43) ALDH1A1MAPTKCNH2SIGMAR1TSHR
Hydrochloric Acid SCHEMBL11499886 0.83 SLC6A4 (0.33) ALDH1A1MAPTSLC6A4MAPK1TAAR1
SCHEMBL9222606 0.79 TAAR1 (0.39) SLC6A2SLC6A4SLC6A3ADRA2BADRA2C
Hydrochloric Acid SCHEMBL7799087 0.79 SIGMAR1 (0.42) ALDH1A1MAPTSLC6A2SLC6A4SLC6A3
SCHEMBL3343241 0.78 TAAR1 (0.47) ALDH1A1MAPTSLC6A2SLC6A4SLC6A3
SCHEMBL6606461 0.78 TAAR1 (0.47) ALDH1A1MAPTSLC6A2SLC6A4SLC6A3
SCHEMBL2600695 0.77 SIGMAR1 (0.44) ALDH1A1MAPTSLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10206393-B2 Solavetivone and 5-epi-β-vetivone as pest repellants and pesticides EVOLVA, INC. (US) 2019-02-19 US claimed
US-9839214-B2 Solavetivone and 5-epi-beta-vertivone as pest repellants and pesticides EVOLVA, INC. (US) 2017-12-12 US claimed
US-20160174552-A1 Solavetivone and 5-Epi-Beta-Vertivone as Pest Repellants and Pesticides EVOLVA, INC. 2016-06-23 US claimed
WO-2014099821-A2 SOLAVETIVONE AND 5-EPI-BETA-VERTIVONE AS PEST REPELLANTS AND PESTICIDES ALLYLIX, INC. (US) 2014-06-26 WO claimed
WO-2014031790-A1 NOOTKATONE AS AN INSECTICIDE AND INSECT REPELLENT ALLYLIX, INC. (US) 2014-02-27 WO claimed
CN-101460680-A Sizing of paper AKZO NOBEL NV (NL) 2009-06-17 CN claimed
US-20240224994-A1 INSECT REPELLANT FORMULATION AND METHOD OF USING SAME UNITED INDUSTRIES CORPORATION 2024-07-11 US disclosed
EP-4054394-B1 WIPE FOR CLEANING AND DISINFECTING OBJECTS AND SURFACES CMC CONSUMER MEDICAL CARE GMBH (DE) 2024-07-10 EP disclosed
EP-4209474-A1 METHOD FOR MODIFYING THE SURFACE PROPERTIES OF ARTIFICIAL STONE AND ARTIFICIAL STONE MODIFIED BY THE METHOD N-Tec GmbH (DE) 2023-07-12 EP disclosed
EP-4054394-A1 CLOTH FOR CLEANING AND DISINFECTING OBJECTS AND SURFACES CMC Consumer Medical Care GmbH (DE) 2022-09-14 EP disclosed
EP-4046491-A1 INSECT REPELLENT FMC Corporation (US) 2022-08-24 EP disclosed
WO-2022071457-A1 COMPOSITION FOR INHIBITING PLAQUE FORMATION サンスター スイス エスエー 2022-04-07 WO disclosed
US-20200163334-A1 INSECT REPELLENT LINTZ, DONNA 2020-05-28 US disclosed
WO-2014031790-A1 NOOTKATONE AS AN INSECTICIDE AND INSECT REPELLENT ALLYLIX, INC. (US) 2014-02-27 WO disclosed
CN-103509180-A Polymer dispersion and process for preparing a polymer dispersion AKZO NOBEL NV 2014-01-15 CN disclosed
CN-101460680-A Sizing of paper AKZO NOBEL NV (NL) 2009-06-17 CN disclosed
CN-101094881-A Polymer dispersion and method for producing a polymer dispersion AKZO NOBEL NV (NL) 2007-12-26 CN disclosed
US-6762162-B1 ACRYLATE MONOMER HAS SYNERGISTIC BIOCIDAL ACTIVITY WITH QUATERNARY AMMONIUM OR SUBSTITUTED GUANIDINE BIOCIDES; HARD SURFACE AND FLOOR CLEANER FORMULATIONS; PH BETWEEN 4 AND 6 S. C. JOHNSON & SON, INC. 2004-07-13 US disclosed
CN-1268874-A Method and composition for cleaning food products to reduce microorganisms PROCTER & GAMBLE (US) 2000-10-04 CN disclosed
US-5391300-A Sorbing polychlorinated biphenyls with polymeric material; desorbing GENERAL ELECTRIC COMPANY (US) 1995-02-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160174552-A1 Solavetivone and 5-Epi-Beta-Vertivone as Pest Repellants and Pesticides GRIK5, SCN5A, API5 SLC6A2 2325/4885SLC6A4 1627/4885SLC6A3 3227/4885
US-10206393-B2 Solavetivone and 5-epi-β-vetivone as pest repellants and pesticides GRIK5, HDAC5, SCN5A SLC6A2 2220/4885SLC6A4 1216/4885SLC6A3 2935/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.