Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acrylamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31441111 | 0.93 | TSHR (0.50) | TSHRALDH1A1TGM2 | |
| SCHEMBL1775597 | 0.93 | TSHR (0.50) | TSHRALDH1A1TGM2 | |
| Potassium Ion SCHEMBL7626089 | 0.90 | TSHR (0.50) | TSHRALDH1A1TGM2 | |
| Lithium Ion SCHEMBL30776952 | 0.90 | TSHR (0.50) | TSHRALDH1A1TGM2 | |
| Acrylamide SCHEMBL27834779 | 0.83 | TSHR (0.47) | TSHRALDH1A1FGFR4 | |
| Acrylamide SCHEMBL3113092 | 0.81 | TSHR (0.44) | TSHRALDH1A1FGFR4TGM2 | |
| SCHEMBL7575540 | 0.78 | TSHR (0.52) | TSHRALDH1A1TGM2 | |
| Acrylamide SCHEMBL19665935 | 0.77 | TSHR (0.50) | TSHRALDH1A1FGFR4 | |
| Water SCHEMBL17782175 | 0.76 | TSHR (0.50) | TSHRALDH1A1TGM2 | |
| SCHEMBL5248938 | 0.75 | TSHR (0.54) | TSHRALDH1A1TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117797043-A | Cosmetic composition comprising a water-soluble or water-dispersible UV-screening agent, a hydrophilic thickener and a hydrophilic surfactant | 莱雅公司 | 2024-04-02 | — | — | CN | claimed |
| US-20230293395-A1 | GELLED COMPOSITION COMPRISING A SHORT-CHAIN FATTY ACID SALT | L'OREAL (FR) | 2023-09-21 | — | — | US | claimed |
| WO-2023141803-A1 | COMPOSITION SUITABLE FOR HIGH CONTENT OF OIL | L'OREAL (FR) | 2023-08-03 | — | — | WO | claimed |
| CN-116115509-A | Cosmetic composition comprising a water-soluble UV filter | 欧莱雅 | 2023-05-16 | — | — | CN | claimed |
| CN-115768397-A | Gelling compositions comprising short chain fatty acid salts | 欧莱雅 | 2023-03-07 | — | — | CN | claimed |
| US-20230028965-A1 | COSMETIC COMPOSITION COMPRISING WATER-SOLUBLE OR WATER-DISPERSIBLE UV-SCREENING AGENTS, HYDROPHILIC THICKENERS AND HYDROPHILIC SURFACTANTS | L'OREAL (FR) | 2023-01-26 | — | — | US | claimed |
| US-20220000754-A1 | PERFUME GEL | L'OREAL (FR) | 2022-01-06 | — | — | US | claimed |
| CN-111511342-A | Compositions comprising AMPS polymers | 莱雅公司 | 2020-08-07 | — | — | CN | claimed |
| CN-107207823-B | Oil-in-water emulsified composition | 莱雅公司 | 2020-04-24 | — | — | CN | claimed |
| WO-2019159726-A1 | COMPOSITION COMPRISING AMPS POLYMER | L'OREAL (FR) | 2019-08-22 | — | — | WO | claimed |
| WO-2016101135-A1 | AN OIL-IN-WATER EMULSIFIED COMPOSITION | L'OREAL (FR) | 2016-06-30 | — | — | WO | claimed |
| US-20050196364-A1 | Transparent self-tanning gels containing a water-soluble/dispersible acrylamido-2-methylpropanesulfonic acid polymer | L'OREAL (FR) | 2005-09-08 | — | — | US | claimed |
| WO-2024130622-A1 | COMPOSITION FOR CARING FOR AND/OR MAKING UP KERATIN MATERIALS | L'OREAL (FR) | 2024-06-27 | — | — | WO | disclosed |
| WO-2024098246-A1 | COMPOSITION FOR CARING FOR KERATIN MATERIALS AND MASK CONTAINING THE SAME | L'OREAL (FR) | 2024-05-16 | — | — | WO | disclosed |
| US-11925699-B2 | Gelled composition comprising a dispersion of solid aggregates | L'OREAL (FR) | 2024-03-12 | — | — | US | disclosed |
| US-20240009108-A1 | COSMETIC COMPOSITION, USE OF A COSMETIC COMPOSITION AND PROCESS OF MANUFACTURING A COSMETIC COMPOSITION | L'OREAL (FR) | 2024-01-11 | — | — | US | disclosed |
| US-20060104936-A1 | Charging/separating cosmetic makeup compositions for keratin fibers | SOCIETE L'OREAL (FR) | 2006-05-18 | — | — | US | disclosed |
| US-20050196364-A1 | Transparent self-tanning gels containing a water-soluble/dispersible acrylamido-2-methylpropanesulfonic acid polymer | L'OREAL (FR) | 2005-09-08 | — | — | US | disclosed |
| US-6905674-B2 | Aqueous photoprotective compositions comprising acrylamido-2-methylpropanesulfonic acid polymers and 4,4-diarylbutadiene UV-A sunscreens | L'OREAL (FR) | 2005-06-14 | — | — | US | disclosed |
| US-20040228815-A1 | Aqueous photoprotective compositions comprising acrylamido-2-methylpropanesulfonic acid polymers and 4,4-diarylbutadiene UV-A sunscreens | L'OREAL (FR) | 2004-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11925699-B2 | Gelled composition comprising a dispersion of solid aggregates | CUTA, KRT18, PLOD3 | TSHR 3645/4885ALDH1A1 1471/4885FGFR4 3715/4885 |
| US-20050196364-A1 | Transparent self-tanning gels containing a water-soluble/dispersible acrylamido-2-methylpropanesulfonic acid polymer | CUTA, MC1R, AMPD1 | TSHR 2802/4885ALDH1A1 2417/4885FGFR4 4169/4885 |
| US-20240009108-A1 | COSMETIC COMPOSITION, USE OF A COSMETIC COMPOSITION AND PROCESS OF MANUFACTURING A COSMETIC COMPOSITION | CUTA, TRPC7, PARN | TSHR 2719/4885ALDH1A1 4037/4885FGFR4 3687/4885 |
| US-20230028965-A1 | COSMETIC COMPOSITION COMPRISING WATER-SOLUBLE OR WATER-DISPERSIBLE UV-SCREENING AGENTS, HYDROPHILIC THICKENERS AND HYDROPHILIC SURFACTANTS | CUTA, DSG1, KRT18 | TSHR 3429/4885ALDH1A1 2393/4885FGFR4 2883/4885 |
| US-20220000754-A1 | PERFUME GEL | CUTA, ACR, ACMSD | TSHR 4665/4885ALDH1A1 477/4885FGFR4 4830/4885 |
| US-20060104936-A1 | Charging/separating cosmetic makeup compositions for keratin fibers | CUTA, KRT18, DSG1 | TSHR 2518/4885ALDH1A1 3521/4885FGFR4 3585/4885 |
| US-20230293395-A1 | GELLED COMPOSITION COMPRISING A SHORT-CHAIN FATTY ACID SALT | KRT18, CUTA, ALG1 | TSHR 4733/4885ALDH1A1 2355/4885FGFR4 1689/4885 |
| US-20040228815-A1 | Aqueous photoprotective compositions comprising acrylamido-2-methylpropanesulfonic acid polymers and 4,4-diarylbutadiene UV-A sunscreens | CUTA, MSH6, ACMSD | TSHR 4418/4885ALDH1A1 2045/4885FGFR4 4392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.