Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29775116 | 0.98 | — | — | |
| SCHEMBL813364 | 0.98 | — | — | |
| SCHEMBL3646018 | 0.98 | — | — | |
| SCHEMBL3935203 | 0.96 | — | — | |
| Chloromethane SCHEMBL3686720 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL1978361 | 0.92 | GPR3 (0.30) | — | |
| SCHEMBL814590 | 0.90 | GPR3 (0.31) | — | |
| SCHEMBL1655227 | 0.88 | KCNH2 (0.32) | — | |
| SCHEMBL4293662 | 0.86 | ALDH1A1 (0.40) | — | |
| SCHEMBL8084759 | 0.85 | MAOB (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460834-B1 | Improved acidic activator-supports and catalysts for olefin polymerization | CHEVRON PHILLIPS CHEMICAL CO (US) | 2015-08-12 | — | — | EP | claimed |
| EP-1807456-B1 | ORGANOCHROMIUM/METALLOCENE COMBINATION CATALYST FOR PRODUCING BIMODAL RESINS | CHEVRON PHILLIPS CHEMICAL CO (US) | 2012-07-11 | — | — | EP | claimed |
| EP-1799726-B1 | TRIALKYLALUMINUM TREATED SUPPORTS | EXXONMOBIL CHEM PATENTS INC (US) | 2011-07-13 | — | — | EP | claimed |
| US-20070055028-A1 | Preparation of polymerization catalyst activators utilizing indole-modified silica supports | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-03-08 | — | — | US | claimed |
| US-20060079394-A1 | Trialkylaluminum treated supports | EXXONMOBIL CHEMICAL PATENTS INC. | 2006-04-13 | — | — | US | claimed |
| US-20050148743-A1 | polymerization catalyst systems comprising an ion-exchange layered silicate, an organoaluminum compound, and a heterocyclic compound | EXXONMOBIL CHEMICAL PATENTS INC. | 2005-07-07 | — | — | US | claimed |
| EP-1155051-B1 | COMPOSITIONS OF PREACTIVATED UNSUPPORTED CATALYST HAVING A GIVEN CONCENTRATION AND METHODS OF USING THEM | UNION CARBIDE CHEM PLASTIC (US) | 2004-10-13 | — | — | EP | claimed |
| EP-0822938-B1 | ENHANCED SYNTHESIS OF RACEMIC METALLOCENES | ALBEMARLE CORP (US) | 1999-06-16 | — | — | EP | claimed |
| EP-0758355-B1 | APPLICATIONS OF ISOTACTIC POLYPROPYLENE, PROCESSES AND PRODUCTS THEREOF | EXXON CHEMICAL PATENTS INC (US) | 1998-12-09 | — | — | EP | claimed |
| US-20140378720-A1 | Processes to Produce Polyalpha-Olefin Compositions | EXXONMOBIL CHEMICAL PATENTS INC. | 2014-12-25 | — | — | US | disclosed |
| US-8748361-B2 | Polyalpha-olefin compositions and processes to produce the same | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2014-06-10 | — | — | US | disclosed |
| EP-1910431-B1 | POLYALPHA-OLEFIN COMPOSITIONS AND PROCESSES TO PRODUCE THE SAME | EXXONMOBIL CHEM PATENTS INC (US) | 2013-11-27 | — | — | EP | disclosed |
| US-20110275772-A1 | Method for Controlling Bimodal Catalyst Activity During Polymerization | UNIVATION TECHNOLOGIES, LLC (US) | 2011-11-10 | — | — | US | disclosed |
| US-7741417-B2 | Preparation of polymerization catalyst activators utilizing indole-modified silica supports | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-06-22 | — | — | US | disclosed |
| US-20030171512-A1 | Polymerization process | MAWSON SIMON (US) | 2003-09-11 | — | — | US | disclosed |
| WO-2003037937-A1 | DIENE FUNCTIONALIZED CATALYST SUPPORTS AND SUPPORTED CATALYST COMPOSITIONS | THE DOW CHEMICAL COMPANY (US) | 2003-05-08 | — | — | WO | disclosed |
| US-20020103310-A1 | Catalyst composition, method of polymerization and polymer therefrom | UNIVATION TECHNOLOGIES, LLC | 2002-08-01 | — | — | US | disclosed |
| US-20020082161-A1 | Diene functionalized catalyst supports and supported catalyst compositions | THE DOW CHEMICAL COMPANY | 2002-06-27 | — | — | US | disclosed |
| US-6313241-B1 | AS PACKAGING MATERIAL | CRYOVAC, INC. | 2001-11-06 | — | — | US | disclosed |
| US-5637666-A | TENSILE STRENGTH, ELASTICITY, LOW MELT TEMPERATURE | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-06-10 | — | — | US | disclosed |