Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 4/20 | 0.48 |
| ▸ | DRD1 known ✓ | P21728 | 1/20 | 0.48 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | CA3 | P07451 | 2/20 | 0.48 |
| ▸ | CA6 | P23280 | 2/20 | 0.48 |
| ▸ | CA5A | P35218 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrazine SCHEMBL28169554 | 0.98 | TSHR (0.55) | TSHRTP53SRD5A2ALDH1A1CA1 | |
| SCHEMBL7034 | 0.98 | TSHR (0.60) | TSHRTP53SRD5A2ALDH1A1CA1 | |
| Hydrazine SCHEMBL28420061 | 0.95 | TSHR (0.57) | TSHRTP53SRD5A2ALDH1A1CA1 | |
| Charcoal, Activated SCHEMBL31491472 | 0.95 | TSHR (0.57) | TSHRTP53SRD5A2ALDH1A1CA1 | |
| Bromide SCHEMBL20984518 | 0.95 | TSHR (0.57) | TSHRTP53SRD5A2ALDH1A1CA1 | |
| Phenylhydrazine SCHEMBL28137921 | 0.94 | LMNA (0.58) | TSHRTP53SRD5A2ALDH1A1MAPT | |
| Oxalic Acid SCHEMBL20984984 | 0.93 | TSHR (0.55) | TSHRTP53SRD5A2ALDH1A1CA1 | |
| Hydrochloric Acid SCHEMBL15688237 | 0.93 | TSHR (0.55) | TSHRTP53SRD5A2ALDH1A1CA1 | |
| Formaldehyde SCHEMBL27512000 | 0.93 | TSHR (0.55) | TSHRTP53SRD5A2ALDH1A1CA1 | |
| Phenylhydrazine SCHEMBL20984743 | 0.89 | LMNA (0.58) | TSHRTP53SRD5A2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025081381-A1 | NANOPARTICLES CAPABLE OF REALIZING CONTROLLED RELEASE OF CARBON MONOXIDE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院深圳先进技术研究院 | 2025-04-24 | — | — | WO | claimed |
| CN-115650960-B | Carboxylesterase 1 specific near infrared fluorescent probe for pesticide residue detection and application thereof | 大连理工大学 | 2024-06-11 | — | — | CN | claimed |
| CN-117414347-A | Nanoparticle capable of controllably releasing carbon monoxide and preparation method and application thereof | 中国科学院深圳先进技术研究院 | 2024-01-19 | — | — | CN | claimed |
| CN-114075146-A | Preparation method of deferasirox impurity | 江苏奥赛康药业有限公司 | 2022-02-22 | — | — | CN | claimed |
| US-11040938-B2 | Continuous flow process for the synthesis of phenylhydrazine salts and substituted phenylhydrazine salts | SHANGHAI HYBRID-CHEM TECHNOLOGIES (CN) | 2021-06-22 | — | — | US | claimed |
| CN-109776563-B | Vomitoxin hapten, preparation method thereof, artificial antigen, kit and vomitoxin detection method | 国家食品安全风险评估中心 | 2020-06-30 | — | — | CN | claimed |
| CN-107663161-B | Continuous flow synthesis process of phenylhydrazine salt and substituted phenylhydrazine salt | 上海惠和化德生物科技有限公司 | 2020-04-10 | — | — | CN | claimed |
| US-20190152896-A1 | Continuous Flow Process For the Synthesis of Phenylhydrazine Salts and Substituted Phenylhydrazine Salts | SHANGHAI HYBRID-CHEM TECHNOLOGIES (CN) | 2019-05-23 | — | — | US | claimed |
| CN-109438294-A | The denitrogenation arylation method and product and application of sulfimide or sulfonamide | 怀化学院 | 2019-03-08 | — | — | CN | claimed |
| CN-106674078-B | A kind of near-infrared ratio that is used to prepare shines the compound of up-conversion nano material, preparation method and application | 郑州大学 | 2019-03-08 | — | — | CN | claimed |
| CN-108623511-A | A kind of indole amides class compound can be used for treating cancer | 南华大学 | 2018-10-09 | — | — | CN | claimed |
| CN-106749288-B | N- (substituted-phenyl) Bi Zuo Bing fraxinellones analog derivative, preparation method and application | 郑州大学 | 2018-07-10 | — | — | CN | claimed |
| CN-107814748-A | A kind of preparation method of 4 hydrazinobenzoic acid hydrochloride | 天津市化学试剂研究所有限公司 | 2018-03-20 | — | — | CN | claimed |
| CN-105733564-B | A kind of Ratiometric fluorescent probe sensitive Mitochondrially targeted pH and its preparation method and application | 郑州大学 | 2018-01-05 | — | — | CN | claimed |
| CN-106749288-A | N (substituted benzene) base Bi Zuo Ji fraxinellones analog derivative, its preparation method and application | 郑州大学 | 2017-05-31 | — | — | CN | claimed |
| CN-106674078-A | Compound for preparing near-infrared rate light-emitting upconversion nanomaterial as well as preparation method and application of compound | 郑州大学 | 2017-05-17 | — | — | CN | claimed |
| CN-106565697-A | Lysosome positioning fluorescence probe, preparation method, and application in arginine detection in near infrared ratio | 郑州大学 | 2017-04-19 | — | — | CN | claimed |
| CN-105733564-A | Mitochondrially-targeted pH-sensitive ratio-type fluorescent probe and preparation method and application thereof | 郑州大学 | 2016-07-06 | — | — | CN | claimed |
| CN-105019013-A | Blue-light emitting monocrystalline material preparation method | UNIV TAIYUAN TECHNOLOGY | 2015-11-04 | — | — | CN | claimed |
| EP-0384769-B1 | Protein labelling | JOHNSON MATTHEY PLC (GB) | 1996-04-24 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11040938-B2 | Continuous flow process for the synthesis of phenylhydrazine salts and substituted phenylhydrazine salts | HPD, TYR, PDK2 | CA2 931/4885DRD1 414/4885PTGS2 2185/4885 |
| US-20190152896-A1 | Continuous Flow Process For the Synthesis of Phenylhydrazine Salts and Substituted Phenylhydrazine Salts | HPD, TYR, PDK2 | CA2 931/4885DRD1 414/4885PTGS2 2185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.