Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.30 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1407277 | 0.97 | — | — | |
| SCHEMBL28738430 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL4596140 | 0.78 | TSHR (0.45) | KDM4ELMNA | |
| SCHEMBL94151 | 0.77 | — | — | |
| SCHEMBL16244957 | 0.77 | KDM4E (0.38) | KDM4ELMNA | |
| SCHEMBL3502798 | 0.76 | SLC1A5 (0.43) | — | |
| SCHEMBL18274734 | 0.76 | NOS3 (0.31) | — | |
| SCHEMBL352049 | 0.76 | SLC1A5 (0.43) | — | |
| Hydrochloric Acid SCHEMBL9018961 | 0.76 | MAPT (0.50) | KDM4ELMNA | |
| SCHEMBL18274735 | 0.76 | NOS3 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110509376-A | The preparation method of faint scent Wood craft | HUAIAN CITY HUAIAN DISTR CHUANGSHI ARTWARE CO LTD | 2019-11-29 | — | — | CN | claimed |
| CN-109352773-A | A kind of preparation method of wooden environment-protective handicraft | 嘉兴保利文化创意有限公司 | 2019-02-19 | — | — | CN | claimed |
| CN-109266183-A | A kind of preparation method of Automobile steel ring surface dark color baking vanish | 安徽江淮车轮有限公司 | 2019-01-25 | — | — | CN | claimed |
| CN-108748542-A | A method of avoid quick growth poplar wood from giving birth to cutting plate | 界首市元宝山木制品有限公司 | 2018-11-06 | — | — | CN | claimed |
| CN-108748556-A | A kind of method of windmill palm vine material dyeing | 安徽戴家工艺有限公司 | 2018-11-06 | — | — | CN | claimed |
| CN-108724396-A | A kind of method for bleaching before wicker products japanning | 安徽华宇工艺品股份有限公司 | 2018-11-02 | — | — | CN | claimed |
| CN-108673679-A | A kind of preparation method of deodorizing antibiotic wicker plaiting article shoe rack | 阜南县宇翔工艺品有限公司 | 2018-10-19 | — | — | CN | claimed |
| CN-108617437-A | A kind of implantation methods promoting Siraitia grosvenorii transplanting survival rate | 界首市家丰家庭农场 | 2018-10-09 | — | — | CN | claimed |
| CN-108382022-A | A kind of preparation method of refratory thread fire-resistant isinglass belt | 铜陵市远维线缆有限公司 | 2018-08-10 | — | — | CN | claimed |
| CN-108048823-A | A kind of method of metal parts mechanical zinc-plating | 马鞍山市恒特重工科技有限公司 | 2018-05-18 | — | — | CN | claimed |
| CN-108017965-A | A kind of preparation method of heat-insulated color steel tile | 太和县盛泰彩钢有限公司 | 2018-05-11 | — | — | CN | claimed |
| CN-108003719-A | A kind of preparation method of heat-insulated container bag | 安徽益邦新材料科技股份有限公司 | 2018-05-08 | — | — | CN | claimed |
| CN-107938176-A | A kind of preparation method of high-strength meltblown non-woven fabrics | 马鞍山市鑫程纳米新材料科技有限公司 | 2018-04-20 | — | — | CN | claimed |
| CN-107739549-A | A kind of method of abandoned project plastics depainting strip | 界首市锦丰塑业有限公司 | 2018-02-27 | — | — | CN | claimed |
| CN-107698338-A | A kind of preparation method of multiple-effect biological matter fertilizer | 安徽省宗正农业科技开发有限公司 | 2018-02-16 | — | — | CN | claimed |
| CN-107419317-A | A kind of method for lifting magnechuck bottom plate wearability | 马鞍山起劲磁塑科技有限公司 | 2017-12-01 | — | — | CN | claimed |
| CN-107263664-A | A kind of preparation method of lightweight clothes hanger | 界首市胜满亿木业有限公司 | 2017-10-20 | — | — | CN | claimed |
| CN-107163876-A | A kind of preparation method of waterproof monofilament fishing net binding agent | 巢湖市荷花渔网有限公司 | 2017-09-15 | — | — | CN | claimed |
| CN-107047143-A | A kind of implantation methods for preventing and treating fairy bamboo leaf spot | 枞阳县弘阳园林绿化有限公司 | 2017-08-18 | — | — | CN | claimed |
| CN-105594737-A | Sterilization disinfectant liquid | WANG FANG | 2016-05-25 | — | — | CN | claimed |