Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Pyromellitic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 4/20 | 0.43 |
| ▸ | PTGS2 known ✓ | P35354 | 2/20 | 0.43 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.41 |
| ▸ | DRD3 known ✓ | P35462 | 1/20 | 0.41 |
| ▸ | KDR known ✓ | P35968 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyromellitic Acid SCHEMBL338944 | 1.00 | ALDH1A1 (0.50) | ALDH1A1ALOX15CYP1A2KMT2ATDP1 | |
| Pyromellitic Acid SCHEMBL11316481 | 1.00 | ALDH1A1 (0.50) | ALDH1A1ALOX15CYP1A2KMT2ATDP1 | |
| Pyromellitic Acid SCHEMBL338946 | 1.00 | ALDH1A1 (0.50) | ALDH1A1ALOX15CYP1A2KMT2ATDP1 | |
| Pyromellitic Acid SCHEMBL11316473 | 1.00 | ALDH1A1 (0.50) | ALDH1A1ALOX15CYP1A2KMT2ATDP1 | |
| Pyromellitic Acid SCHEMBL22127 | 0.96 | ALDH1A1 (0.53) | ALDH1A1ALOX15CYP1A2KMT2ATDP1 | |
| Pyromellitic Acid SCHEMBL22443 | 0.96 | ALDH1A1 (0.53) | ALDH1A1ALOX15CYP1A2KMT2ATDP1 | |
| Pyromellitic Acid SCHEMBL692530 | 0.92 | ALDH1A1 (0.50) | ALDH1A1ALOX15CYP1A2KMT2ATDP1 | |
| Pyromellitic Acid SCHEMBL9485109 | 0.92 | ALDH1A1 (0.50) | ALDH1A1ALOX15CYP1A2KMT2ATDP1 | |
| Pyromellitic Acid SCHEMBL22982083 | 0.92 | ALDH1A1 (0.50) | ALDH1A1ALOX15CYP1A2KMT2ATDP1 | |
| Pyromellitic Acid SCHEMBL21328420 | 0.92 | ALDH1A1 (0.50) | ALDH1A1ALOX15CYP1A2KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119971784-B | Preparation method of nanofiltration membrane with high pollution resistance | 华东理工大学 | 2026-05-12 | — | — | CN | claimed |
| CN-120132621-A | Preparation method of polyamide composite membrane with high pollution resistance | 华东理工大学 | 2025-06-13 | — | — | CN | claimed |
| CN-120132623-A | Composite reverse osmosis membrane material | 泉州职业技术大学 | 2025-06-13 | — | — | CN | claimed |
| CN-119971784-A | Preparation method of nanofiltration membrane with high pollution resistance | 华东理工大学 | 2025-05-13 | — | — | CN | claimed |
| CN-118649567-B | Application of polyamide nanofiltration membrane in selective separation of new pollutants and salt ions in water environment | 浙江大学 | 2025-02-07 | — | — | CN | claimed |
| CN-118807467-B | Nanofiltration membrane and preparation method thereof | 湖南沁森高科新材料有限公司 | 2025-01-17 | — | — | CN | claimed |
| US-20240399317-A1 | METHOD FOR PREPARING SELF-SUPPORTING COMPOSITE NANOFILTRATION MEMBRANE | TIANGONG UNIVERSITY (CN) | 2024-12-05 | — | — | US | claimed |
| CN-118807467-A | Nanofiltration membrane and preparation method thereof | 湖南沁森高科新材料有限公司 | 2024-10-22 | — | — | CN | claimed |
| CN-118649567-A | Application of polyamide nanofiltration membrane in selective separation of new pollutants and salt ions in water environment | 浙江大学 | 2024-09-17 | — | — | CN | claimed |
| CN-118320630-A | Preparation method of compact chlorine-resistant composite nanofiltration membrane | 启成（江苏）净化科技有限公司 | 2024-07-12 | — | — | CN | claimed |
| CN-115709003-B | Positively charged composite nanofiltration membrane and preparation method thereof | 湖南沁森高科新材料有限公司 | 2023-05-23 | — | — | CN | claimed |
| CN-114904399-B | Interfacial polymerization method based on eutectic solvent and alkane, polyamide composite membrane and preparation method thereof | 山东中康国创先进印染技术研究院有限公司 | 2023-05-16 | — | — | CN | claimed |
| CN-115382399-A | Preparation method of nano particle composite nanofiltration membrane based on UiO-66 and product thereof | 上海淳罡环境科技有限公司 | 2022-11-25 | — | — | CN | claimed |
| CN-111282447-B | Preparation method of desalination composite membrane with nanoscale ultrathin separation layer | 青岛致用新材料科技有限公司 | 2022-03-04 | — | — | CN | claimed |
| CN-113694740-A | Positively charged nanofiltration membrane prepared from ionized monomers and preparation method thereof | 华中科技大学 | 2021-11-26 | — | — | CN | claimed |
| US-20120255898-A1 | SEMIPERMEABLE POLYMERS AND METHOD FOR PRODUCING SAME | ELTRON RESEARCH & DEVELOPMENT, INC. (US) | 2012-10-11 | — | — | US | claimed |
| WO-2010042250-A2 | SEMIPERMEABLE POLYMERS AND METHOD FOR PRODUCING SAME | ELTRON RESEARCH AND DEVELOPMENT, INC. (US) | 2010-04-15 | — | — | WO | claimed |
| US-20100006495-A1 | SEMIPERMEABLE POLYMERS AND METHOD FOR PRODUCING SAME | ELTRON RESEARCH AND DEVELOPMENT, INC. (US) | 2010-01-14 | — | — | US | claimed |
| EP-0227043-A2 | Composite semipermeable membrane and process for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-07-01 | — | — | EP | claimed |
| US-4557978-A | POLYMERIZING AN AROMATIC ACENE HYDROCARBON AND AN ACIDIC MONONER; POLYACENEQUINONE RADICAL TYPE COATING | PRIMARY ENERGY RESEARCH CORPORATION (US) | 1985-12-10 | — | — | US | claimed |