Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Moroxydine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.35 |
| ▸ | MMP1 known ✓ | P03956 | 1/20 | 0.32 |
| ▸ | MMP8 known ✓ | P22894 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Moroxydine SCHEMBL1447794 | 1.00 | LMNA (0.48) | LMNACA12CA1CA9CA2 | |
| Moroxydine SCHEMBL27330736 | 0.98 | LMNA (0.47) | LMNACA12CA1CA9CA2 | |
| Moroxydine SCHEMBL246710 | 0.98 | LMNA (0.50) | LMNACA12CA1CA9CA2 | |
| Moroxydine SCHEMBL8166651 | 0.98 | LMNA (0.50) | LMNACA12CA1CA9CA2 | |
| Moroxydine SCHEMBL28205796 | 0.96 | LMNA (0.46) | LMNACA12CA1CA9CA2 | |
| Moroxydine SCHEMBL27849674 | 0.96 | LMNA (0.48) | LMNACA12CA1CA9CA2 | |
| Moroxydine SCHEMBL16011669 | 0.92 | LMNA (0.46) | LMNACA12CA1CA9CA2 | |
| Moroxydine SCHEMBL11647873 | 0.91 | LMNA (0.42) | LMNACA12CA1CA9CA2 | |
| Moroxydine SCHEMBL28846598 | 0.89 | MMP1 (0.44) | LMNACA12CA1CA9ALDH1A1 | |
| Moroxydine SCHEMBL27909468 | 0.89 | LMNA (0.43) | LMNACA12CA1CA9CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 810 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4255191-B1 | CAPSIDIC NANOPARTICLES OF COWPEA MOSAIC VIRUS WITHOUT GENETIC MATERIAL FOR THE TREATMENT OF A DISEASE OF THE AERIAL PART OF A PLANT | DIAMANTE SOC BENEFIT S R L (IT) | 2024-10-09 | — | — | EP | claimed |
| US-20240049724-A1 | CAPSIDIC NANOPARTICLES OF COWPEA MOSAIC VIRUS WITHOUT GENETIC MATERIAL FOR THE TREATMENT OF A DISEASE OF THE AERIAL PART OF A PLANT | DIAMANTE SOC BENEFIT S R L (IT) | 2024-02-15 | — | — | US | claimed |
| EP-4255191-A1 | CAPSIDIC NANOPARTICLES OF COWPEA MOSAIC VIRUS WITHOUT GENETIC MATERIAL FOR THE TREATMENT OF A DISEASE OF THE AERIAL PART OF A PLANT | Diamante Societa' Benefit S.r.l. (IT) | 2023-10-11 | — | — | EP | claimed |
| WO-2022118355-A1 | CAPSIDIC NANOPARTICLES OF COWPEA MOSAIC VIRUS WITHOUT GENETIC MATERIAL FOR THE TREATMENT OF A DISEASE OF THE AERIAL PART OF A PLANT | DIAMANTE SRL (IT) | 2022-06-09 | — | — | WO | claimed |
| CN-110448633-A | The pharmaceutical composition and preparation method thereof for treating vaginitis | LIU YUMEI | 2019-11-15 | — | — | CN | claimed |
| CN-110367203-A | A kind of artificial batch feeding packaging microbracon hebetor living body at bee method | 贵州省烟草公司贵阳市公司 | 2019-10-25 | — | — | CN | claimed |
| CN-110339294-A | A kind of combination of Chinese tradiational and Western medicine reagent combination for treating acne | 孟娟 | 2019-10-18 | — | — | CN | claimed |
| CN-110235858-A | A method of Storage tobacco cacac moth is killed so that cacac moth is host's feeding transport microbracon hebetor bee pupa | 贵州省烟草公司贵阳市公司 | 2019-09-17 | — | — | CN | claimed |
| CN-110235857-A | A method of transport microbracon hebetor is raised for host with cacac moth and kills Storage tobacco cacac moth at bee | 贵州省烟草公司贵阳市公司 | 2019-09-17 | — | — | CN | claimed |
| CN-110235859-A | A kind of method of artificial batch feeding packaging microbracon hebetor living body bee pupa | 贵州省烟草公司贵阳市公司 | 2019-09-17 | — | — | CN | claimed |
| US-5514505-A | SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE | XEROX CORPORATION (US) | 1996-05-07 | — | — | US | claimed |
| CN-1119103-A | 'Kangbingwang' injection for treating animal disease and preparing process thereof | LIU FANGGE (CN) | 1996-03-27 | — | — | CN | claimed |
| CN-1119102-A | Soluble powder for treating fowl disease | LIU FANGGE (CN) | 1996-03-27 | — | — | CN | claimed |
| CN-1086959-A | A kind of viroses of plant prophylactic and manufacture method thereof | JIANG BINGSHENG (CN) | 1994-05-25 | — | — | CN | claimed |
| WO-1994002055-A1 | PORTABLE, INTEGRATED, UNIVERSALLY ADJUSTABLE POSITION CONTROL SYSTEM | TRUMAN PRODUCTS (US) | 1994-02-03 | — | — | WO | claimed |
| WO-1992019097-A1 | SELF-CONTAINED PROGRAMMABLE WATERING DEVICE FOR POT PLANTS | BAISSUS CLAUDE (FR) | 1992-11-12 | — | — | WO | claimed |
| EP-0357685-A1 | METHOD AND APPARATUS FOR ASSURING ADEQUATE ACCESS TO SYSTEM RESOURCES BY PROCESSORS IN A MULTIPROCESSOR COMPUTER SYSTEM. | DIGITAL EQUIPMENT CORP (US) | 1990-03-14 | — | — | EP | claimed |
| WO-1990000485-A1 | A PROCESS AND DEVICE FOR MONITORING THE ACTIVE SUSPENSION OF THE BODYWORK OF A RAILWAY VEHICLE | DURAND CHARLES RENE (FR) | 1990-01-25 | — | — | WO | claimed |
| WO-1988008570-A1 | METHOD AND APPARATUS FOR ASSURING ADEQUATE ACCESS TO SYSTEM RESOURCES BY PROCESSORS IN A MULTIPROCESSOR COMPUTER SYSTEM | DIGITAL EQUIPMENT CORPORATION (US) | 1988-11-03 | — | — | WO | claimed |
| EP-0039641-B1 | PUNCTUALLY ACTING BRAKE | SOCIETE ANONYME D.B.A. (FR) | 1984-07-18 | — | — | EP | claimed |