Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.54 |
| ▸ | ABL1 known ✓ | P00519 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.95 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91986 | 0.97 | — | — | |
| SCHEMBL29682476 | 0.97 | — | — | |
| Nitrogen SCHEMBL10696802 | 0.95 | CYP3A4 (0.86) | CYP3A4ALDH1A1TSHRTDP1SMN1; SMN2 | |
| Hypochlorous Acid SCHEMBL11428546 | 0.93 | CYP3A4 (0.91) | CYP3A4ALDH1A1TSHRTDP1SMN1; SMN2 | |
| Sulfuric Acid SCHEMBL27605690 | 0.85 | CYP3A4 (0.76) | CYP3A4ALDH1A1TSHRTDP1SMN1; SMN2 | |
| Sulfuric Acid SCHEMBL31129159 | 0.85 | CYP3A4 (0.76) | CYP3A4ALDH1A1TSHRTDP1SMN1; SMN2 | |
| Formic Acid Methyl Ester SCHEMBL28165664 | 0.82 | CYP3A4 (0.70) | CYP3A4ALDH1A1TSHRTDP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL131186 | 0.80 | CYP3A4 (0.62) | CYP3A4ALDH1A1TSHRTDP1SMN1; SMN2 | |
| SCHEMBL560430 | 0.79 | CYP3A4 (0.68) | CYP3A4ALDH1A1TSHRTDP1SMN1; SMN2 | |
| SCHEMBL92153 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118839999-A | Peak regulation and frequency modulation oriented energy storage power station output characteristic evaluation method and device | 国网新能源云技术有限公司 | 2024-10-25 | — | — | CN | claimed |
| CN-111147282-B | Device, method and storage medium for automatically maintaining DRCP connection pool | 中国建设银行股份有限公司 | 2022-09-20 | — | — | CN | claimed |
| US-3962336-A | Process for the preparation of 5-chloro-2-toluidine | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-06-08 | — | — | US | claimed |
| EP-4693151-A2 | DEVICES, SYSTEMS, AND METHODS FOR FACILITATING LOW TRUST AND ZERO TRUST VALUE TRANSFERS | Veritaseum, Inc. (US) | 2026-02-11 | — | — | EP | disclosed |
| CN-119954978-A | Preparation method and application of tray root polysaccharide | 吉林化工学院 | 2025-05-09 | — | — | CN | disclosed |
| CN-115037691-B | Multicast mask table negotiation method and equipment | 新华三技术有限公司合肥分公司 | 2025-05-02 | — | — | CN | disclosed |
| US-20250014278-A1 | POINTCLOUD PROCESSING, ESPECIALLY FOR USE WITH BUILDING INTELLIGENCE MODELLING (BIM) | AUTODESK, INC. | 2025-01-09 | — | — | US | disclosed |
| CN-119254397-A | Method and device for rapidly switching unicast traffic of cross-device link aggregation system | 新华三技术有限公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-119042407-A | JPCCP pipeline state intelligent monitoring system and construction regulation and control method | 中建八局西南建设工程有限公司 | 2024-11-29 | — | — | CN | disclosed |
| CN-118839999-A | Peak regulation and frequency modulation oriented energy storage power station output characteristic evaluation method and device | 国网新能源云技术有限公司 | 2024-10-25 | — | — | CN | disclosed |
| CN-118784487-A | Communication speed limiting method, communication system, network device, readable storage medium, and program product | 中国电信股份有限公司技术创新中心 | 2024-10-15 | — | — | CN | disclosed |
| US-20110034440-A1 | HOMOCYSTEINE SYNTHASE INHIBITOR | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-02-10 | — | — | US | disclosed |
| EP-2275404-A1 | HOMOCYSTEINE SYNTHASE INHIBITOR | Mitsubishi Tanabe Pharma Corporation (JP) | 2011-01-19 | — | — | EP | disclosed |
| US-4224025-A | Process for the dyeing and printing of paper materials in different hues using a single coupling component | CIBA-GEIGY CORPORATION (US) | 1980-09-23 | — | — | US | disclosed |
| US-4224027-A | Process for the production of water-insoluble azo dyestuffs on the fiber with polyphosphate | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-09-23 | — | — | US | disclosed |
| US-4183727-A | Process for the production of water-insoluble azo dyestuffs on the fiber | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-01-15 | — | — | US | disclosed |
| US-4165967-A | HYDROXY-PYRIDINE OR PYRIDONE COUPLERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1979-08-28 | — | — | US | disclosed |
| US-4065254-A | DIAZO DYES, LEATHER, COTTON, WOOL | CIBA-GEIGY CORPORATION (US) | 1977-12-27 | — | — | US | disclosed |
| US-4034043-A | PRODUCTION OF 2-AMINO-5-CHLORO-TOLUENE HYDROCHLORIDE | CIBA-GEIGY CORPORATION (US) | 1977-07-05 | — | — | US | disclosed |
| US-3962336-A | Process for the preparation of 5-chloro-2-toluidine | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034440-A1 | HOMOCYSTEINE SYNTHASE INHIBITOR | BHMT, CBS, BHMT2 | GAA 1870/4885ABL1 2662/4885CYP3A4 1270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.