Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.37 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | LAP3 | P28838 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446187 | 0.98 | — | — | |
| Iodide SCHEMBL4843397 | 0.96 | TSHR (0.50) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Bromide SCHEMBL4449404 | 0.96 | TSHR (0.50) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Acetic Acid SCHEMBL4442312 | 0.92 | TSHR (0.47) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL28390981 | 0.83 | TSHR (0.39) | TSHRZDHHC20ZDHHC2 | |
| SCHEMBL22868489 | 0.78 | TSHR (0.54) | TSHRALDH1A1MAPK1TDP1CYP2C19 | |
| SCHEMBL11169697 | 0.77 | ZDHHC20 (0.49) | TSHRALDH1A1MAPK1ZDHHC20ZDHHC2 | |
| SCHEMBL176143 | 0.76 | TSHR (0.52) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL4442955 | 0.76 | — | — | |
| SCHEMBL5170699 | 0.76 | TSHR (0.56) | TSHRALDH1A1MAPK1TDP1ZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118873440-A | Composition with conditioning and puffing effects and application of composition in shampoo products | 广州凡岛网络科技有限公司 | 2024-11-01 | — | — | CN | claimed |
| CN-114601744-B | Delivery of surfactant soluble anti-dandruff agents | 宝洁公司 | 2024-12-20 | — | — | CN | disclosed |
| CN-118873440-A | Composition with conditioning and puffing effects and application of composition in shampoo products | 广州凡岛网络科技有限公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-117794879-A | Dry mixtures of building materials comprising solid vinyl ester resins | 瓦克化学股份公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-109715131-B | Low viscosity hair care compositions | 宝洁公司 | 2022-04-26 | — | — | CN | disclosed |
| CN-108697596-B | Personal care compositions with zinc-containing layered materials | 宝洁公司 | 2021-09-07 | — | — | CN | disclosed |
| US-10975350-B2 | Cell culture substrate and method of making thereof | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2021-04-13 | — | — | US | disclosed |
| CN-107072934-B | Personal care compositions and methods of preparation | 宝洁公司 | 2021-01-22 | — | — | CN | disclosed |
| CN-106794128-B | Methods of achieving improved volume and combability using anti-dandruff personal care compositions comprising pre-emulsified formulations | 宝洁公司 | 2020-09-15 | — | — | CN | disclosed |
| US-20180355310-A1 | A CELL CULTURE SUBSTRATE AND METHOD OF MAKING THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2018-12-13 | — | — | US | disclosed |
| US-6423469-B1 | IONOMER COMPRISING UNSATURATED COMONOMERS OF QUATERNIZED N-ALKYLATED AROMATIC HETEROCYCLIC, ORGANOONIUM, AND THIOSULFATE COMPOUNDS; LITHOGRAPHY | EASTMAN KODAK COMPANY | 2002-07-23 | — | — | US | disclosed |
| US-6410202-B1 | HYDROPHILIC HEAT SENSITIVE ELEMENTS | EASTMAN KODAK COMPANY | 2002-06-25 | — | — | US | disclosed |
| US-6399268-B1 | Processless direct write imaging member containing polymer grafted carbon and methods of imaging and printing | KODAK POLYCHROME GRAPHICS LLC | 2002-06-04 | — | — | US | disclosed |
| EP-1093417-A1 | PROCESSLESS DIRECT WRITE IMAGING MEMBER CONTAINING POLYMER GRAFTED CARBON AND METHODS OF IMAGING AND PRINTING | Kodak Polychrome Graphics Company Ltd. (US) | 2001-04-25 | — | — | EP | disclosed |
| US-6190831-B1 | HEAT-SENSITIVE POLYMER HAS RECURRING UNITS CONTAINING AN N-ALKYLATED AROMATIC HETEROCYCLIC GROUP OR AN ORGANOONIUM GROUP THAT REACTS TO PROVIDE INCREASED OLEOPHILICITY | KODAK POLYCHROME GRAPHICS LLC | 2001-02-20 | — | — | US | disclosed |
| US-6190830-B1 | UNITS CONTAINING AN ORGANOAMMONIUM, ORGANOPHOSPHONIUM OR ORGANOSULFONIUM GROUP THAT REACTS TO PROVIDE INCREASED OLEOPHILICITY (INK RECEPTIVITY) IN RESPONSE TO HEAT. | KODAK POLYCHROME GRAPHICS LLC | 2001-02-20 | — | — | US | disclosed |
| US-6159657-A | Thermal imaging composition and member containing sulfonated ir dye and methods of imaging and printing | EASTMAN KODAK COMPANY (US) | 2000-12-12 | — | — | US | disclosed |
| WO-2000063025-A1 | PROCESSLESS DIRECT WRITE IMAGING MEMBER CONTAINING POLYMER GRAFTED CARBON AND METHODS OF IMAGING AND PRINTING | KODAK POLYCHROME GRAPHICS COMPANY LTD. (US) | 2000-10-26 | — | — | WO | disclosed |
| EP-0990517-A2 | Processless direct write printing plate having heat sensitive positively-charged polymers and methods of imaging and printing | Kodak Polychrome Graphics LLC (US) | 2000-04-05 | — | — | EP | disclosed |
| EP-0990516-A1 | Processless direct write printing plate and methods of imaging and printing | Kodak Polychrome Graphics LLC (US) | 2000-04-05 | — | — | EP | disclosed |