Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 known ✓ | Q99720 | 1/20 | 0.47 |
| ▸ | HDAC3 known ✓ | O15379 | 3/20 | 0.46 |
| ▸ | EGFR known ✓ | P00533 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 3/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 2/20 | 0.49 |
| ▸ | CES1 | P23141 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20307697 | 0.98 | NAAA (0.61) | NAAAEPHX1ALDH1A1HTTCES2 | |
| SCHEMBL4353659 | 0.97 | NAAA (0.58) | NAAAEPHX1ALDH1A1HTTCES2 | |
| Hydrochloric Acid SCHEMBL11041256 | 0.93 | GAA (0.51) | NAAAALDH1A1HTTCES2CES1 | |
| SCHEMBL11310671 | 0.92 | GAA (0.53) | NAAAALDH1A1HTTCES2CES1 | |
| SCHEMBL22221979 | 0.90 | MAPT (0.56) | NAAAALDH1A1CES1MEN1KMT2A | |
| SCHEMBL11913604 | 0.88 | MAPT (0.54) | NAAAALDH1A1CES1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11664928 | 0.86 | THRA (0.61) | NAAAEPHX1ALDH1A1HTTCES2 | |
| SCHEMBL11137757 | 0.84 | HPGD (0.54) | NAAAALDH1A1CES2CES1MEN1 | |
| Dipentylamine SCHEMBL28010569 | 0.83 | NAAA (0.58) | NAAAEPHX1ALDH1A1HTTCES2 | |
| SCHEMBL16248729 | 0.83 | L3MBTL1 (0.48) | NAAAALDH1A1CES1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12436479-B2 | Carrier for forming electrophotographic image, developer for forming electrophotographic image, electrophotographic image forming method, electrophotographic image forming apparatus, and process cartridge | RICOH COMPANY, LTD. (JP) | 2025-10-07 | — | — | US | disclosed |
| US-20250306493-A1 | CARRIER, TWO-COMPONENT DEVELOPING AGENT, PROCESS CARTRIDGE, IMAGE FORMING APPARATUS, AND IMAGE FORMING METHOD | RICOH COMPANY, LTD. (JP) | 2025-10-02 | — | — | US | disclosed |
| US-12379678-B2 | Carrier for forming electrophotographic image, developer, image forming method, image forming apparatus, and process cartridge | RICOH COMPANY, LTD. (JP) | 2025-08-05 | — | — | US | disclosed |
| US-12306582-B2 | Carrier for forming electrophotographic image, developer for forming electrophotographic image, electrophotographic image forming method, electrophotographic image forming apparatus, and process cartridge | RICOH COMPANY, LTD. (JP) | 2025-05-20 | — | — | US | disclosed |
| US-12147192-B2 | Carrier for developing electrostatic latent image, two-component developer, image forming apparatus, process cartridge, and image forming method | RICOH COMPANY, LTD. (JP) | 2024-11-19 | — | — | US | disclosed |
| US-12105472-B2 | Carrier for forming electrophotographic image, developing agent for forming electrophotographic image, method of forming electrophotographic image, electrophotographic image forming apparatus, and process cartridge | RICOH COMPANY, LTD. (JP) | 2024-10-01 | — | — | US | disclosed |
| US-20240302763-A1 | IMAGE FORMING METHOD, CARRIER, DEVELOPER, AND IMAGE FORMING APPARATUS | RICOH COMPANY, LTD. (JP) | 2024-09-12 | — | — | US | disclosed |
| US-20240295834-A1 | CARRIER, DEVELOPING AGENT, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE | RICOH COMPANY, LTD. (JP) | 2024-09-05 | — | — | US | disclosed |
| EP-4372472-A1 | ELECTROPHOTOGRAPHIC IMAGE FORMING CARRIER, ELECTROPHOTOGRAPHIC IMAGE FORMING DEVELOPER, ELECTROPHOTOGRAPHIC IMAGE FORMING METHOD, AND ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS | Ricoh Company, Ltd. (JP) | 2024-05-22 | — | — | EP | disclosed |
| EP-4198635-B1 | DEVELOPING APPARATUS, DEVELOPER FOR ELECTROPHOTOGRAPHIC IMAGE FORMATION, ELECTROPHOTOGRAPHIC IMAGE FORMING METHOD, AND ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS | RICOH CO LTD (JP) | 2024-05-22 | — | — | EP | disclosed |
| EP-0259819-B1 | Toner for developing electrostatic images, binder resin therefor and process for production thereof | CANON KK (JP) | 1994-12-07 | — | — | EP | disclosed |
| US-5333059-A | Electrostatic imaging apparatus and facsimile apparatus employing toner with low aldehyde content | CANON KABUSHIKI KAISHA (JP) | 1994-07-26 | — | — | US | disclosed |
| US-5310812-A | Solution and suspension polymerization, styrene-acrylate copolymer | CANON KABUSHIKI KAISHA (JP) | 1994-05-10 | — | — | US | disclosed |
| US-5298354-A | Binder resin and colorant | CANON KABUSHIKI KAISHA (JP) | 1994-03-29 | — | — | US | disclosed |
| US-5219947-A | Fixability, anti-offset and antisticking properties | CANON KABUSHIKI KAISHA (JP) | 1993-06-15 | — | — | US | disclosed |
| US-5135833-A | Low temperature-fixing toner comprising a binder resin containing 5-10% tetrahydrofuran-insoluble matter having a specific molecular weight profile; offset resistance; antisoilants | CANON KABUSHIKI KAISHA (JP) | 1992-08-04 | — | — | US | disclosed |
| US-5126224-A | Very low content of odorous benzaldehyde impurity in styrene polymer binder | CANON KABUSHIKI KAISHA (JP) | 1992-06-30 | — | — | US | disclosed |
| EP-0438181-A2 | Electrostatic image developing toner and fixing method | CANON KABUSHIKI KAISHA (JP) | 1991-07-24 | — | — | EP | disclosed |
| EP-0417812-A2 | Electrostatic image developing toner and process for its production, and binder resin and process for its production | CANON KABUSHIKI KAISHA (JP) | 1991-03-20 | — | — | EP | disclosed |
| US-4966829-A | Mixture of a colorant, magnetic powder, a binder resin; good fixability, anti-sticking and pulverizability | CANON KABUSHIKI KAISHA (JP) | 1990-10-30 | — | — | US | disclosed |