Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.40 |
| ▸ | S1PR1 known ✓ | P21453 | 1/20 | 0.37 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1683348 | 1.00 | LMNA (0.42) | LMNAFDPSCYP2D6SPHK1TP53 | |
| SCHEMBL16794807 | 0.98 | LMNA (0.43) | LMNAFDPSCYP2D6SPHK1TP53 | |
| SCHEMBL28464782 | 0.98 | LMNA (0.43) | LMNAFDPSCYP2D6SPHK1TP53 | |
| SCHEMBL28459947 | 0.98 | LMNA (0.43) | LMNAFDPSCYP2D6SPHK1TP53 | |
| SCHEMBL8546915 | 0.98 | LMNA (0.43) | LMNAFDPSCYP2D6SPHK1TP53 | |
| Bromide SCHEMBL9488266 | 0.96 | LMNA (0.42) | LMNAFDPSCYP2D6SPHK1TP53 | |
| Bromide SCHEMBL7774753 | 0.96 | LMNA (0.42) | LMNAFDPSCYP2D6SPHK1TP53 | |
| Hydrochloric Acid SCHEMBL9487806 | 0.92 | LMNA (0.44) | LMNAFDPSCYP2D6SPHK1TP53 | |
| SCHEMBL28461198 | 0.90 | CA2 (0.38) | LMNAFDPSTP53OPRM1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6890712 | 0.90 | FDPS (0.44) | LMNAFDPSCYP2D6SPHK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3573461-B1 | ANTIMICROBIAL, NON-THROMBOGENIC POLYMER COMPOSITIONS | LUBRIZOL ADVANCED MAT INC (US) | 2026-04-22 | — | — | EP | disclosed |
| EP-4155334-A1 | ANTIMICROBIAL THERMOPLASTIC POLYURETHANES | Lubrizol Advanced Materials, Inc. (US) | 2023-03-29 | — | — | EP | disclosed |
| US-11578205-B2 | Antimicrobial, non-thrombogenic polymer composition | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2023-02-14 | — | — | US | disclosed |
| EP-3574032-B1 | ANTIMICROBIAL THERMOPLASTIC POLYURETHANES | LUBRIZOL ADVANCED MAT INC (US) | 2022-08-31 | — | — | EP | disclosed |
| US-20220153917-A1 | Antimicrobial Thermoplastic Polyuethanes | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2022-05-19 | — | — | US | disclosed |
| US-20210277231-A1 | Antimicrobial, Non-Thrombogenic Polymer Composition | LUBRIZOL ADVANCED MAT INC (US) | 2021-09-09 | — | — | US | disclosed |
| WO-2018140910-A1 | ANTIMICROBIAL THERMOPLASTIC POLYURETHANES | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2018-08-02 | — | — | WO | disclosed |
| WO-2018140911-A1 | ANTIMICROBIAL, NON-THROMBOGENIC POLYMER COMPOSITIONS | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2018-08-02 | — | — | WO | disclosed |
| US-20110124772-A1 | ANTIMICROBIAL POLYMERS AND THEIR USES | DSM IP ASSETS B.V. (NL) | 2011-05-26 | — | — | US | disclosed |
| EP-2309851-A2 | ANTIMICROBIAL POLYMERS AND THEIR USES | DSM IP Assets B.V. (NL) | 2011-04-20 | — | — | EP | disclosed |
| WO-2009148880-A2 | ANTIMICROBIAL POLYMERS AND THEIR USES | DSM IP ASSETS B.V. (NL) | 2009-12-10 | — | — | WO | disclosed |