Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB known ✓ | P27338 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AGXT | P21549 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27576321 | 0.98 | HPGD (0.41) | HPGDMAOBCALM1CYP3A4CYP2C19 | |
| Hydrochloric Acid SCHEMBL9820122 | 0.86 | PLA2G1B (0.37) | KMT2AALDH1A1KDM4EL3MBTL1IDO1 | |
| Hydrochloric Acid SCHEMBL9820172 | 0.86 | ALDH1A1 (0.39) | HPGDCYP3A4CYP2C19ALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL9820181 | 0.86 | HTT (0.40) | HPGDCYP2C19MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL9820169 | 0.86 | SIGMAR1 (0.40) | HPGDCYP3A4CYP2C19MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9820111 | 0.86 | CYP2C19 (0.44) | CYP3A4CYP2C19MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL9820179 | 0.81 | CYP19A1 (0.39) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9820158 | 0.81 | LTA4H (0.52) | CYP3A4ALDH1A1TSHRIDO1TP53 | |
| Hydrochloric Acid SCHEMBL9820161 | 0.81 | IDO1 (0.43) | HPGDCYP2C19ALDH1A1L3MBTL1IDO1 | |
| Hydrochloric Acid SCHEMBL9819973 | 0.81 | LTA4H (0.52) | L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11859074-B2 | Curable fluoroelastomer composition | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2024-01-02 | — | — | US | claimed |
| CN-111742004-B | Curable composition | 3M创新有限公司 | 2022-07-19 | — | — | CN | claimed |
| US-20210292533-A1 | CURABLE FLUOROELASTOMER COMPOSITION | 3M INNOVATIVE PROPERTIES COMPANY | 2021-09-23 | — | — | US | claimed |
| US-20210189111-A1 | CURABLE FLUOROELASTOMER COMPOSITION | 3M INNOVATIVE PROPERTIES COMPANY | 2021-06-24 | — | — | US | claimed |
| EP-3837309-A1 | CURABLE FLUOROELASTOMER COMPOSITION | 3M Innovative Properties Company (US) | 2021-06-23 | — | — | EP | claimed |
| EP-3755739-A1 | CURABLE FLUOROELASTOMER COMPOSITION | 3M Innovative Properties Company (US) | 2020-12-30 | — | — | EP | claimed |
| US-20200369867-A1 | CURABLE FLUOROELASTOMER COMPOSITION | 3M INNOVATIVE PROPERTIES COMPANY | 2020-11-26 | — | — | US | claimed |
| CN-111757908-A | Curable fluoroelastomer compositions | 3M创新有限公司 | 2020-10-09 | — | — | CN | claimed |
| CN-111757906-A | Curable fluoroelastomer compositions | 3M创新有限公司 | 2020-10-09 | — | — | CN | claimed |
| CN-111742004-A | Blends of crosslinking agents for fluoroelastomers | 3M创新有限公司 | 2020-10-02 | — | — | CN | claimed |
| WO-2020035776-A1 | CURABLE FLUOROELASTOMER COMPOSITION | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2020-02-20 | — | — | WO | claimed |
| WO-2019159070-A1 | CURABLE FLUOROELASTOMER COMPOSITION | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2019-08-22 | — | — | WO | claimed |
| US-5371143-A | Polymer blend composition of fluorinated elastomers, thermoplastic polymers and thermoplastics elastomers | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-12-06 | — | — | US | claimed |
| EP-0182299-B1 | A CURABLE FLUOROELASTOMER COMPOSITION | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1991-04-03 | — | — | EP | claimed |
| US-4912171-A | Blend of addition polymer, polyhydroxy compound, organo-onium compound and acid acceptor | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-03-27 | — | — | US | claimed |
| US-4882390-A | AND POLYHYDROXY COMPOUND | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-11-21 | — | — | US | claimed |
| EP-0182299-A2 | A curable fluoroelastomer composition | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1986-05-28 | — | — | EP | claimed |
| JP-1197550-A | — | — | None | — | — | JP | disclosed |
| EP-0292747-A2 | A shaped article of a crosslinked elastomer | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1988-11-30 | — | — | EP | disclosed |
| EP-0182299-A2 | A curable fluoroelastomer composition | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1986-05-28 | — | — | EP | disclosed |