Hydrochloric Acid

Hydrochloric Acid

SCHEMBL197657

CC(C)(C)C(N)c1ccccc1.Cl

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DPP4 known ✓ P27487 2/20 0.50
SLC6A2 known ✓ P23975 2/20 0.48
SLC6A4 known ✓ P31645 2/20 0.48
SLC6A3 known ✓ Q01959 2/20 0.48
ADRA2A known ✓ P08913 1/20 0.44
ADRA2C known ✓ P18825 1/20 0.44
F2 P00734 1/20 0.50
ALDH1A1 P00352 1/20 0.48
LMNA P02545 1/20 0.44
HIF1A Q16665 1/20 0.44
KDM4E B2RXH2 1/20 0.44
TAAR1 Q96RJ0 1/20 0.43
AOC3 Q16853 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL23292667 1.00 DPP4 (0.50) DPP4F2SLC6A2SLC6A4SLC6A3
SCHEMBL8761844 0.97 DPP4 (0.52) DPP4F2SLC6A2SLC6A4SLC6A3
SCHEMBL1358135 0.97 DPP4 (0.52) DPP4F2SLC6A2SLC6A4SLC6A3
SCHEMBL8761852 0.97 DPP4 (0.52) DPP4F2SLC6A2SLC6A4SLC6A3
Iodide SCHEMBL4994551 0.95 DPP4 (0.50) DPP4F2SLC6A2SLC6A4SLC6A3
Water SCHEMBL8528911 0.95 DPP4 (0.50) DPP4F2SLC6A2SLC6A4SLC6A3
Hydrochloric Acid SCHEMBL20241471 0.85 DPP4 (0.46) DPP4F2SLC6A2SLC6A4SLC6A3
Hydrochloric Acid SCHEMBL56184 0.83 ALDH1A1 (0.48) DPP4F2SLC6A2SLC6A4SLC6A3
Hydrochloric Acid SCHEMBL57497 0.83 ALDH1A1 (0.48) DPP4F2SLC6A2SLC6A4SLC6A3
Hydrochloric Acid SCHEMBL27730332 0.83 ALDH1A1 (0.48) DPP4F2SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118234840-A Quick-drying multipurpose cleaning and sanitizing compositions and methods of use thereof 埃科莱布美国股份有限公司 2024-06-21 CN claimed
CN-115516069-A Low foaming cleaning composition 埃科莱布美国股份有限公司 2022-12-23 CN claimed
CN-113736200-A Antibacterial super absorbent resin composite material and preparation method thereof 威高集团有限公司 2021-12-03 CN claimed
WO-2021241851-A1 ANTIBACTERIAL COMPOSITION FOR FIBERS WITH IMPROVED WASHING RESISTANCE (주)컬러케미 2021-12-02 WO claimed
US-11166458-B2 Wet wipes comprising antimicrobial coating compositions ALLIED BIOSCIENCE, INC. (US) 2021-11-09 US claimed
CN-110628530-A Cleaning compositions, methods of manufacture and uses thereof 莫尔豪斯医学院 2019-12-31 CN claimed
US-20180243790-A1 WET WIPES COMPRISING ANTIMICROBIAL COATING COMPOSITIONS ALLIED BIOSCIENCE, INC. (US) 2018-08-30 US claimed
US-8894907-B2 Process of making a cleaning implement comprising functionally active fibers THE CLOROX COMPANY (US) 2014-11-25 US claimed
US-8827122-B2 Non-flammable plastic aerosol THE CLOROX COMPANY (US) 2014-09-09 US claimed
US-20120261439-A1 Non-Flammable Plastic Aerosol THE CLOROX COMPANY 2012-10-18 US claimed
US-20110060052-A1 Biocidal aldehyde composition for oil and gas extraction MARTIN HOWARD 2011-03-10 US claimed
US-20100080993-A1 Electrospun Functional Fibers THE CLOROX COMPANY 2010-04-01 US claimed
US-7179849-B2 Antimicrobial compositions containing colloids of oligodynamic metals C. R. BARD, INC. (US) 2007-02-20 US claimed
US-6015836-A Chemical disinfectant employing dual chain quaternary ammonium compounds with iodine MARTIN HOWARD (US) 2000-01-18 US claimed
US-5322856-A Dual quaternary ammonium chloride, para-tert-amyl phenol, ortho-phenyl phenol, citric or acetic acid, sodium citrate, isopropyl or ethyl alcohol, triethanolamine hydrochloride and water MARTIN HOWARD 1994-06-21 US claimed
US-5152996-A Moistened, flexible sheets of cellulose fibers EASTMAN KODAK COMPANY (US) 1992-10-06 US claimed
US-4472283-A QUATERNARY AMMONIUM COMPOUNDS TO SLOW LOSS OF CARBON DIOXIDE CITICORP. USA, INC. 1984-09-18 US claimed
US-4336151-A AN ETHYLENE OXIDE FATTY AMIDE ADDUCT, POLYOXYETHYLENE GLYCOL WITH WITHOUT LANOLIN MODIFIER, PROTEIN HYDROLYZATES, ALLANTOIN, OR HEXYLENE GLYCOL AMERICAN CYANAMID COMPANY (US) 1982-06-22 US claimed
US-4336152-A MALTODEXTRIN ADDITIVE AMERICAN CYANAMID COMPANY (US) 1982-06-22 US claimed
US-4173643-A 4-ISOTHIAZOLINE-3-ONES ROHM AND HAAS COMPANY (US) 1979-11-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11166458-B2 Wet wipes comprising antimicrobial coating compositions WIZ, CUTA, WASHC4 DPP4 1508/4885SLC6A2 3279/4885SLC6A4 2734/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.