Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28522442 | 0.88 | CYP2C19 (0.51) | CYP2C19LMNAALDH1A1MAPK1THRB | |
| SCHEMBL16324840 | 0.86 | CYP2C19 (0.63) | CYP2C19LMNAALDH1A1MAPK1THRB | |
| SCHEMBL11856721 | 0.84 | LMNA (0.59) | CYP2C19LMNAALDH1A1MAPK1THRB | |
| SCHEMBL4231086 | 0.82 | LMNA (0.57) | CYP2C19LMNAALDH1A1MAPK1THRB | |
| SCHEMBL11638988 | 0.82 | LMNA (0.57) | CYP2C19LMNAALDH1A1MAPK1THRB | |
| SCHEMBL1629588 | 0.82 | LMNA (0.57) | CYP2C19LMNAALDH1A1MAPK1THRB | |
| SCHEMBL11726262 | 0.82 | LMNA (0.57) | CYP2C19LMNAALDH1A1MAPK1THRB | |
| SCHEMBL15752503 | 0.81 | LMNA (0.68) | CYP2C19LMNAALDH1A1MAPK1THRB | |
| SCHEMBL11826732 | 0.81 | LMNA (0.56) | CYP2C19LMNAALDH1A1MAPK1THRB | |
| SCHEMBL11828991 | 0.81 | LMNA (0.56) | CYP2C19LMNAALDH1A1MAPK1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 135 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119432011-A | Low-dielectric epoxy resin for copper-clad plate and processing technology thereof | 江苏耀鸿电子有限公司 | 2025-02-14 | — | — | CN | claimed |
| CN-118986933-A | Nanometer preparation for delivering medicine on demand aiming at inherent barrier of pancreatic cancer, and preparation method and application thereof | 复旦大学 | 2024-11-22 | — | — | CN | claimed |
| CN-118593722-A | Chemotherapeutic drug-polymer conjugate capable of realizing particle size conversion of hypoxia response and preparation method and application thereof | 复旦大学 | 2024-09-06 | — | — | CN | claimed |
| CN-115429755-B | Micelle drug delivery system for pH response charge inversion and hypoxia response drug release and preparation method thereof | 复旦大学 | 2024-05-14 | — | — | CN | claimed |
| CN-117343015-A | 1-methyl-d 3 Preparation of (E) -2- (carbamoyloxymethyl) -5-nitroimidazole | 四川大学 | 2024-01-05 | — | — | CN | claimed |
| CN-113030309-B | Method for detecting nitroimidazole antibiotics in honey and sample treatment method thereof | 浙江工业大学 | 2022-12-23 | — | — | CN | claimed |
| CN-115429755-A | Micelle drug delivery system for pH-responsive charge reversal and hypoxia-responsive drug release and preparation method thereof | 复旦大学 | 2022-12-06 | — | — | CN | claimed |
| CN-110630452-B | Protective coating for improving low-temperature resistance of wind driven generator blade | 安徽国成顺风风力发电有限公司 | 2020-11-03 | — | — | CN | claimed |
| CN-110630452-A | Protective coating for improving low-temperature resistance of wind driven generator blade | 安徽国成顺风风力发电有限公司 | 2019-12-31 | — | — | CN | claimed |
| CN-110078669-A | A kind of green synthesis method of loxidazole and its deuterated derivative | 东莞暨南大学研究院 | 2019-08-02 | — | — | CN | claimed |
| CN-104797562-B | The preparation method and its usage of phenoxymethyl nitro imidazole derivatives | 赛诺菲 | 2017-10-03 | — | — | CN | claimed |
| US-9758488-B2 | Method for preparing phenyloxymethyl-nitro-imidazole derivatives and use of same | SANOFI (FR) | 2017-09-12 | — | — | US | claimed |
| EP-2922822-B1 | METHOD FOR PREPARING PHENYLOXYMETHYL-NITRO-IMIDAZOLE DERIVATIVES AND USE OF SAME | SANOFI SA (FR) | 2016-12-28 | — | — | EP | claimed |
| US-20150291536-A1 | METHOD FOR PREPARING PHENYLOXYMETHYL-NITRO-IMIDAZOLE DERIVATIVES AND USE OF SAME | SANOFI (FR) | 2015-10-15 | — | — | US | claimed |
| EP-2922822-A1 | METHOD FOR PREPARING PHENYLOXYMETHYL-NITRO-IMIDAZOLE DERIVATIVES AND USE OF SAME | Sanofi (FR) | 2015-09-30 | — | — | EP | claimed |
| CN-104797562-A | Method for preparing phenyloxymethyl-nitro-imidazole derivatives and use of same | SANOFI SA | 2015-07-22 | — | — | CN | claimed |
| WO-2014079497-A1 | METHOD FOR PREPARING PHENYLOXYMETHYL-NITRO-IMIDAZOLE DERIVATIVES AND USE OF SAME | DRUGS FOR NEGLECTED DISEASES INITIATIVE (DNDI) (CH) | 2014-05-30 | — | — | WO | claimed |
| US-20140031289-A1 | POLY(ORGANOPHOSPHAZENE) CONTAINING DEGRADATION CONTROLLABLE IONIC GROUP, PREPARATION METHOD THEREOF AND USE THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-01-30 | — | — | US | claimed |
| CN-101949898-A | Method for detecting residual quantity of multiple alkaline drugs in animal derived food | SHANGHAI ANPEL SCIENT INSTR CO LTD | 2011-01-19 | — | — | CN | claimed |
| EP-4086242-B1 | 5-[(2,4-DINITROPHENOXY)METHYL]-1-METHYL-2-NITRO-L H-IMIDAZOLE AND ITS PHARMACEUTICAL USE | RIVUS PHARMACEUTICALS INC (US) | 2026-04-08 | — | — | EP | disclosed |
| EP-4655286-A2 | COMPOUNDS AND THEIR USE IN THE TREATMENT OF NON-VIRAL DISEASES AND INFECTIONS | Technische Universität München, in Vertretung des Freistaats Bayern (DE) | 2025-12-03 | — | — | EP | disclosed |
| US-20250214944-A1 | Novel Phenyl Derivatives | Rivus Pharmaceuticals, Inc. | 2025-07-03 | — | — | US | disclosed |
| CN-115531345-B | Hypoxia response bionic nano delivery system and preparation method thereof | 复旦大学 | 2025-03-11 | — | — | CN | disclosed |
| CN-119432011-A | Low-dielectric epoxy resin for copper-clad plate and processing technology thereof | 江苏耀鸿电子有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-118986933-A | Nanometer preparation for delivering medicine on demand aiming at inherent barrier of pancreatic cancer, and preparation method and application thereof | 复旦大学 | 2024-11-22 | — | — | CN | disclosed |
| CN-118593722-A | Chemotherapeutic drug-polymer conjugate capable of realizing particle size conversion of hypoxia response and preparation method and application thereof | 复旦大学 | 2024-09-06 | — | — | CN | disclosed |
| WO-2024156883-A2 | COMPOUNDS AND THEIR USE IN THE TREATMENT OF NON-VIRAL DISEASES AND INFECTIONS | Technische Universität München (DE) | 2024-08-02 | — | — | WO | disclosed |
| CN-115429755-B | Micelle drug delivery system for pH response charge inversion and hypoxia response drug release and preparation method thereof | 复旦大学 | 2024-05-14 | — | — | CN | disclosed |
| US-11935803-B2 | Resin composition, laminate, semiconductor wafer with resin composition layer, substrate for mounting semiconductor with resin composition layer and semiconductor device | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2024-03-19 | — | — | US | disclosed |
| CN-117343015-A | 1-methyl-d 3 Preparation of (E) -2- (carbamoyloxymethyl) -5-nitroimidazole | 四川大学 | 2024-01-05 | — | — | CN | disclosed |
| US-20230365559-A1 | NOVEL AMINOPYRIDINES AND THEIR USE IN TREATING CANCER | AUCKLAND UNISERVICES LIMITED (NZ) | 2023-11-16 | — | — | US | disclosed |
| CN-117024351-A | Novel phenyl derivatives | 里维斯制药股份有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-116669725-A | Novel aminopyridine and use thereof in the treatment of cancer | 奥克兰联合服务有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-110167918-B | Novel Phenyl Derivatives | 里维斯制药股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| EP-4217357-A1 | NOVEL AMINOPYRIDINES AND THEIR USE IN TREATING CANCER | Auckland Uniservices Limited (NZ) | 2023-08-02 | — | — | EP | disclosed |
| CN-115948495-A | Method for screening bacterial quorum sensing inhibitor by using inhibitory siderophore | 海南大学 | 2023-04-11 | — | — | CN | disclosed |
| CN-115785607-A | Preparation method and application of magnetic imprinted polymer | 中国水产科学研究院南海水产研究所 | 2023-03-14 | — | — | CN | disclosed |
| CN-115531345-A | Hypoxic response bionic nano delivery system and preparation method thereof | 复旦大学 | 2022-12-30 | — | — | CN | disclosed |
| CN-113030309-B | Method for detecting nitroimidazole antibiotics in honey and sample treatment method thereof | 浙江工业大学 | 2022-12-23 | — | — | CN | disclosed |
| CN-115429755-A | Micelle drug delivery system for pH-responsive charge reversal and hypoxia-responsive drug release and preparation method thereof | 复旦大学 | 2022-12-06 | — | — | CN | disclosed |
| EP-4086242-A1 | 5-[(2,4-DINITROPHENOXY)METHYL]-1-METHYL-2-NITRO-L H-IMIDAZOLE AND ITS PHARMACEUTICAL USE | Rivus Pharmaceuticals, Inc. (US) | 2022-11-09 | — | — | EP | disclosed |
| CN-112004845-B | Resin composition, laminate, semiconductor wafer with resin composition layer, substrate, and semiconductor device | 三菱瓦斯化学株式会社 | 2022-05-31 | — | — | CN | disclosed |
| WO-2022064430-A1 | NOVEL AMINOPYRIDINES AND THEIR USE IN TREATING CANCER | AUCKLAND UNISERVICES LIMITED (NZ) | 2022-03-31 | — | — | WO | disclosed |
| US-20220048865-A1 | Novel Phenyl Derivatives | Rivus Pharmaceuticals, Inc. | 2022-02-17 | — | — | US | disclosed |
| US-20210277221-A1 | RESIN COMPOSITION, LAMINATE, SEMICONDUCTOR WAFER WITH RESIN COMPOSITION LAYER, SUBSTRATE FOR MOUNTING SEMICONDUCTOR WITH RESIN COMPOSITION LAYER AND SEMICONDUCTOR DEVICE | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2021-09-09 | — | — | US | disclosed |
| US-20210238144-A1 | Phenyl Derivatives | Rivus Pharmaceuticals, Inc. | 2021-08-05 | — | — | US | disclosed |
| CN-113030309-A | Method for detecting nitroimidazole antibiotics in honey and sample treatment method thereof | 浙江工业大学 | 2021-06-25 | — | — | CN | disclosed |
| EP-2825877-B1 | RETENTION INDEX STANDARDS FOR LIQUID CHROMATOGRAPHY | NAT RES COUNCIL CANADA (CA) | 2021-05-26 | — | — | EP | disclosed |
| EP-3786200-A1 | RESIN COMPOSITION, LAMINATE, RESIN COMPOSITION LAYER-ATTACHED SEMICONDUCTOR WAFER, SUBSTRATE FOR MOUNTING RESIN COMPOSITION LAYER-ATTACHED SEMICONDUCTOR, AND SEMICONDUCTOR DEVICE | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2021-03-03 | — | — | EP | disclosed |
| CN-110078669-B | Green synthesis method of metronidazole and deuterated derivatives thereof | 东莞暨南大学研究院 | 2021-02-23 | — | — | CN | disclosed |
| CN-110078669-B | Green synthesis method of metronidazole and deuterated derivatives thereof | 东莞暨南大学研究院 | 2021-02-23 | — | — | CN | disclosed |
| US-20200399225-A1 | Novel Phenyl Derivatives | Rivus Pharmaceuticals, Inc. | 2020-12-24 | — | — | US | disclosed |
| CN-112004845-A | Resin composition, laminate, semiconductor wafer with resin composition layer, substrate for mounting semiconductor with resin composition layer, and semiconductor device | 三菱瓦斯化学株式会社 | 2020-11-27 | — | — | CN | disclosed |
| CN-110630452-B | Protective coating for improving low-temperature resistance of wind driven generator blade | 安徽国成顺风风力发电有限公司 | 2020-11-03 | — | — | CN | disclosed |
| US-10618875-B2 | Phenyl derivatives | Rivus Pharmaceuticals, Inc. (US) | 2020-04-14 | — | — | US | disclosed |
| CN-110630452-A | Protective coating for improving low-temperature resistance of wind driven generator blade | 安徽国成顺风风力发电有限公司 | 2019-12-31 | — | — | CN | disclosed |
| US-20190337903-A1 | Novel Phenyl Derivatives | Rivus Pharmaceuticals, Inc. | 2019-11-07 | — | — | US | disclosed |
| EP-2671581-B1 | Compositions and methods for treating cancer | THRESHOLD PHARMACEUTICALS INC (US) | 2019-10-02 | — | — | EP | disclosed |
| CN-110078669-A | A kind of green synthesis method of loxidazole and its deuterated derivative | 东莞暨南大学研究院 | 2019-08-02 | — | — | CN | disclosed |
| CN-110078669-A | A kind of green synthesis method of loxidazole and its deuterated derivative | 东莞暨南大学研究院 | 2019-08-02 | — | — | CN | disclosed |
| CN-104797562-B | The preparation method and its usage of phenoxymethyl nitro imidazole derivatives | 赛诺菲 | 2017-10-03 | — | — | CN | disclosed |
| US-9758488-B2 | Method for preparing phenyloxymethyl-nitro-imidazole derivatives and use of same | SANOFI (FR) | 2017-09-12 | — | — | US | disclosed |
| US-9758488-B2 | Method for preparing phenyloxymethyl-nitro-imidazole derivatives and use of same | SANOFI (FR) | 2017-09-12 | — | — | US | disclosed |
| EP-2922822-B1 | METHOD FOR PREPARING PHENYLOXYMETHYL-NITRO-IMIDAZOLE DERIVATIVES AND USE OF SAME | SANOFI SA (FR) | 2016-12-28 | — | — | EP | disclosed |
| US-20160244435-A1 | EXPANDED THERAPEUTIC POTENTIAL IN NITROHETEROARYL ANTIMICROBIALS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-08-25 | — | — | US | disclosed |
| US-20160244435-A1 | EXPANDED THERAPEUTIC POTENTIAL IN NITROHETEROARYL ANTIMICROBIALS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-08-25 | — | — | US | disclosed |
| US-20160244435-A1 | EXPANDED THERAPEUTIC POTENTIAL IN NITROHETEROARYL ANTIMICROBIALS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-08-25 | — | — | US | disclosed |
| EP-3010345-A1 | EXPANDED THERAPEUTIC POTENTIAL IN NITROHETEROARYL ANTIMICROBIALS | The Regents of The University of California (US) | 2016-04-27 | — | — | EP | disclosed |
| EP-2336141-B1 | PHOSPHORAMIDATE ALKYLATOR PRODRUGS | THRESHOLD PHARMACEUTICALS INC (US) | 2016-03-30 | — | — | EP | disclosed |
| US-9226932-B2 | Phosphoramidate alkylator prodrugs | THRESHOLD PHARMACEUTICALS, INC. (US) | 2016-01-05 | — | — | US | disclosed |
| US-20150291536-A1 | METHOD FOR PREPARING PHENYLOXYMETHYL-NITRO-IMIDAZOLE DERIVATIVES AND USE OF SAME | SANOFI (FR) | 2015-10-15 | — | — | US | disclosed |
| US-20150291536-A1 | METHOD FOR PREPARING PHENYLOXYMETHYL-NITRO-IMIDAZOLE DERIVATIVES AND USE OF SAME | SANOFI (FR) | 2015-10-15 | — | — | US | disclosed |
| EP-2922822-A1 | METHOD FOR PREPARING PHENYLOXYMETHYL-NITRO-IMIDAZOLE DERIVATIVES AND USE OF SAME | Sanofi (FR) | 2015-09-30 | — | — | EP | disclosed |
| EP-2922822-A1 | METHOD FOR PREPARING PHENYLOXYMETHYL-NITRO-IMIDAZOLE DERIVATIVES AND USE OF SAME | Sanofi (FR) | 2015-09-30 | — | — | EP | disclosed |
| CN-104797562-A | Method for preparing phenyloxymethyl-nitro-imidazole derivatives and use of same | SANOFI SA | 2015-07-22 | — | — | CN | disclosed |
| CN-104797562-A | Method for preparing phenyloxymethyl-nitro-imidazole derivatives and use of same | SANOFI SA | 2015-07-22 | — | — | CN | disclosed |
| CN-104558184-A | Monoclonal antibody, enzyme-linked immunosorbent assay method and kit for detecting nitroimidazoles | UNIV HUAZHONG AGRICULTURAL | 2015-04-29 | — | — | CN | disclosed |
| US-9017726-B2 | Biodegradable and thermosensitive poly(organophosphazene)-superparamagnetic nanoparticle complex, preparation method and use thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2015-04-28 | — | — | US | disclosed |
| CN-104402826-A | Hydroxyl dimetridazole preparation method | CHINA INST VETERINARY DRUGS CONTROL | 2015-03-11 | — | — | CN | disclosed |
| WO-2014205414-A1 | EXPANDED THERAPEUTIC POTENTIAL IN NITROHETEROARYL ANTIMICROBIALS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-12-24 | — | — | WO | disclosed |
| WO-2014205414-A1 | EXPANDED THERAPEUTIC POTENTIAL IN NITROHETEROARYL ANTIMICROBIALS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-12-24 | — | — | WO | disclosed |
| US-20140170240-A1 | Phosphoramidate Alkylator Prodrugs | THRESHOLD PHARMACEUTICALS, INC. (US) | 2014-06-19 | — | — | US | disclosed |
| WO-2014079497-A1 | METHOD FOR PREPARING PHENYLOXYMETHYL-NITRO-IMIDAZOLE DERIVATIVES AND USE OF SAME | DRUGS FOR NEGLECTED DISEASES INITIATIVE (DNDI) (CH) | 2014-05-30 | — | — | WO | disclosed |
| WO-2014079497-A1 | METHOD FOR PREPARING PHENYLOXYMETHYL-NITRO-IMIDAZOLE DERIVATIVES AND USE OF SAME | DRUGS FOR NEGLECTED DISEASES INITIATIVE (DNDI) (CH) | 2014-05-30 | — | — | WO | disclosed |
| CN-103048401-B | Determining method for 15 kinds of forbidden nitro imidazoles antibiotics in cosmetics | CHINESE ACAD INSP & QUARANTINE | 2014-04-30 | — | — | CN | disclosed |
| US-8664204-B2 | Phosphoramidate alkylator prodrugs | THRESHOLD PHARMACEUTICALS, INC. (US) | 2014-03-04 | — | — | US | disclosed |
| US-20140031289-A1 | POLY(ORGANOPHOSPHAZENE) CONTAINING DEGRADATION CONTROLLABLE IONIC GROUP, PREPARATION METHOD THEREOF AND USE THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-01-30 | — | — | US | disclosed |
| US-8586020-B2 | Poly(organophosphazene) composition for biomaterials | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-11-19 | — | — | US | disclosed |
| US-20130303778-A1 | PHOSPHORAMIDATE ALKYLATOR PRODRUGS | THRESHOLD PHARMACEUTICALS, INC. | 2013-11-14 | — | — | US | disclosed |
| US-8507464-B2 | Phosphoramidate alkylator prodrugs | THRESHOLD PHARMACEUTICALS, INC. (US) | 2013-08-13 | — | — | US | disclosed |
| CN-103048401-A | Determining method for 15 kinds of forbidden nitro imidazoles antibiotics in cosmetics | CHINESE ACAD INSP & QUARANTINE | 2013-04-17 | — | — | CN | disclosed |
| US-20130004455-A1 | POLY(ORGANOPHOSPHAZENE) COMPOSITION FOR BIOMATERIALS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-01-03 | — | — | US | disclosed |
| EP-2540764-A2 | Poly(organophosphazene) composition for biomaterials | Korea Institute of Science and Technology (KR) | 2013-01-02 | — | — | EP | disclosed |
| US-8299088-B2 | Compositions and methods for treating cancer | THRESHOLD PHARMACEUTICALS, INC. (US) | 2012-10-30 | — | — | US | disclosed |
| US-8299088-B2 | Compositions and methods for treating cancer | THRESHOLD PHARMACEUTICALS, INC. (US) | 2012-10-30 | — | — | US | disclosed |
| CN-101571526-B | Detection method for simultaneously measuring residue of nitroimidazoles drugs in royal jelly | INSPECTION AND QUARANTINE TECHNOLOGY CT ZHEJIANG ENTRY EXIT INSPECTION AND QUARANTINE BUREAU | 2012-07-04 | — | — | CN | disclosed |
| US-20120121517-A1 | BIODEGRADABLE AND THERMOSENSITIVE POLY(ORGANOPHOSPHAZENE)-SUPERPARAMAGNETIC NANOPARTICLE COMPLEX, PREPARATION METHOD AND USE THEREOF | Korean Institute of Science and Technology of Seoul, Republic of Korea | 2012-05-17 | — | — | US | disclosed |
| US-20110251159-A1 | Phosphoramidate Alkylator Prodrugs | THRESHOLD PHARMACEUTICALS, INC. (US) | 2011-10-13 | — | — | US | disclosed |
| CN-102161679-A | Compositions and methods for treating cancer | THRESHOLD PHARMACEUTICALS INC | 2011-08-24 | — | — | CN | disclosed |
| US-8003625-B2 | Phosphoramidate alkylator prodrugs | THRESHOLD PHARMACEUTICALS, INC. (US) | 2011-08-23 | — | — | US | disclosed |
| EP-2336141-A2 | Phosphoramidate alkylator prodrugs | Threshold Pharmaceuticals, Inc. (US) | 2011-06-22 | — | — | EP | disclosed |
| CN-101949898-A | Method for detecting residual quantity of multiple alkaline drugs in animal derived food | SHANGHAI ANPEL SCIENT INSTR CO LTD | 2011-01-19 | — | — | CN | disclosed |
| US-20100137254-A1 | PHOSPHORAMIDATE ALKYLATOR PRODRUGS | IMMUNOGENESIS, INC. | 2010-06-03 | — | — | US | disclosed |
| US-20090312276-A1 | Compositions and Methods for Treating Cancer | IMMUNOGENESIS, INC. | 2009-12-17 | — | — | US | disclosed |
| US-20090312276-A1 | Compositions and Methods for Treating Cancer | IMMUNOGENESIS, INC. | 2009-12-17 | — | — | US | disclosed |
| CN-101571526-A | Detection method for simultaneously measuring residue of nitroimidazoles drugs in royal jelly | INS & QUAR TECH CT ZHEJIANG (CN) | 2009-11-04 | — | — | CN | disclosed |
| US-7550496-B2 | Compositions and methods for treating cancer | THRESHOLD PHARMACEUTICALS, INC. (US) | 2009-06-23 | — | — | US | disclosed |
| US-7550496-B2 | Compositions and methods for treating cancer | THRESHOLD PHARMACEUTICALS, INC. (US) | 2009-06-23 | — | — | US | disclosed |
| US-20080145372-A1 | Bioreductively-Activated Prodrugs | ANGIOGENE, PHARMACEUTICALS LIMITED (GB) | 2008-06-19 | — | — | US | disclosed |
| EP-1896040-A2 | PHOSPHORAMIDATE ALKYLATOR PRODRUGS | Threshold Pharmaceuticals, Inc. (US) | 2008-03-12 | — | — | EP | disclosed |
| CN-101044150-A | Bioreductively-activated prodrugs | ANGIOGENE PHARM LTD (GB) | 2007-09-26 | — | — | CN | disclosed |
| WO-2007002931-A2 | PHOSPHORAMIDATE ALKYLATOR PRODRUGS | THRESHOLD PHARMACEUTICALS, INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| CN-1791403-A | Compositions and methods for treating cancer | THRESHOLD PHARMACEUTICALS INC (US) | 2006-06-21 | — | — | CN | disclosed |
| EP-1622608-A2 | COMPOSITIONS AND METHODS FOR TREATING CANCER | Threshold Pharmaceuticals, Inc. (US) | 2006-02-08 | — | — | EP | disclosed |
| WO-2004087075-A2 | COMPOSITIONS AND METHODS FOR TREATING CANCER | THRESHOLD PHARMACEUTICALS, INC. (US) | 2004-10-14 | — | — | WO | disclosed |
| WO-2002064091-A2 | MELANOCORTIN METALLOPEPTIDES FOR TREATMENT OF SEXUAL DYSFUNCTION | PALATIN TECHNOLOGIES, INC. (US) | 2002-08-22 | — | — | WO | disclosed |
| EP-1173414-A1 | N-PROTECTED AMINES AND THEIR USE AS PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064864-A9 | N-PROTECTED AMINES AND THEIR USE AS PRODRUGS | CANCER RES CAMPAIGN TECH (GB) | 2001-12-27 | — | — | WO | disclosed |
| WO-2000064864-A1 | N-PROTECTED AMINES AND THEIR USE AS PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2000-11-02 | — | — | WO | disclosed |
| EP-0006463-B1 | PROCESS FOR THE PRODUCTION OF 2-SUBSTITUTED 1-ALKYL-NITROIMIDAZOLES | BASF Aktiengesellschaft (DE) | 1981-11-25 | — | — | EP | disclosed |
| US-4267349-A | Process for the preparation of 2-substituted-alkyl-1-alkyl-nitroimidazoles | BASF AKTIENGESELLSCHAFT (DE) | 1981-05-12 | — | — | US | disclosed |
| US-4232165-A | 2-Substituted-1-alkyl-nitroimidazoles | BASF AKTIENGESELLSCHAFT (DE) | 1980-11-04 | — | — | US | disclosed |
| US-4105763-A | 1-Methyl-2-(phenyl-oxymethyl)-5-nitro-imidazoles | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-08-08 | — | — | US | disclosed |
| US-4080340-A | Nitroimidazoles | MERCK & CO., INC. (US) | 1978-03-21 | — | — | US | disclosed |
| US-4065567-A | Substituted nitroimidazolyl thiadiazoles and oxadiazoles as antibacterial agents and growth promoting compounds | AMERICAN CYANAMID COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-4053482-A | 1-METHYL-2-(SUBSTITUTED THIOMETHYL)-5-NITRO-IMIDAZOLES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-10-11 | — | — | US | disclosed |
| US-4046896-A | 1-Methyl-2-(pyridyl-oxymethyl)-5-nitro-imidazoles | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-09-06 | — | — | US | disclosed |
| US-4042705-A | 1-Methyl-2-(phenyl-oxymethyl)-5-nitro-imidazoles and process for their manufacture | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-08-16 | — | — | US | disclosed |
| US-4031232-A | 1-Alkyl-2-(phenoxymethyl)-5-nitro-imidazoles and process for their manufacture | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-06-21 | — | — | US | disclosed |
| US-4010176-A | Isoxazole substituted nitroimidazoles | MERCK & CO., INC. (US) | 1977-03-01 | — | — | US | disclosed |
| US-3991200-A | Substituted nitroimidazolyl thiadiazoles and oxadiazoles as antibacterial agents and growth promoting compounds | AMERICAN CYANAMID COMPANY (US) | 1976-11-09 | — | — | US | disclosed |
| US-3984560-A | IMIDAZOLES | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-10-05 | — | — | US | disclosed |
| US-3973019-A | Pharmaceutical compositions containing 1,4-bis-(5'-nitroimidazolyl-2'-methylene-imino) piperazine compounds for treating protozoal diseases and methods for treating such diseases | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-08-03 | — | — | US | disclosed |
| US-3969520-A | 2-Amino-4[2-(1-lower alkyl-5-nitro-2-imidiazolyl)vinyl]pyrimidines for treating protozoal and bacterial infections | ISTITUTO CHEMIOTERAPICO ITALIANO S.P.A. (IT) | 1976-07-13 | — | — | US | disclosed |
| US-3951963-A | 0-(Substituted-aminoalkyl)-5-nitroimidazole-(2)-aldoximes | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-04-20 | — | — | US | disclosed |
| US-3951963-A | 0-(Substituted-aminoalkyl)-5-nitroimidazole-(2)-aldoximes | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (18 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291536-A1 | METHOD FOR PREPARING PHENYLOXYMETHYL-NITRO-IMIDAZOLE DERIVATIVES AND USE OF SAME | TPMT, TET2, NNMT | CYP2C19 119/4885LMNA 3511/4885ALDH1A1 2561/4885 |
| US-20100137254-A1 | PHOSPHORAMIDATE ALKYLATOR PRODRUGS | TYMP, PAICS, PNP | CYP2C19 2771/4885LMNA 3316/4885ALDH1A1 1886/4885 |
| US-10618875-B2 | Phenyl derivatives | TFAM, PC, PCK2 | CYP2C19 2964/4885LMNA 3023/4885ALDH1A1 1185/4885 |
| US-20130004455-A1 | POLY(ORGANOPHOSPHAZENE) COMPOSITION FOR BIOMATERIALS | PHOSPHO1, PGLS, PHYKPL | CYP2C19 1287/4885LMNA 2870/4885ALDH1A1 2323/4885 |
| US-20120121517-A1 | BIODEGRADABLE AND THERMOSENSITIVE POLY(ORGANOPHOSPHAZENE)-SUPERPARAMAGNETIC NANOPARTICLE COMPLEX, PREPARATION METHOD AND USE THEREOF | PHOSPHO1, HSPA2, FEM1B | CYP2C19 3446/4885LMNA 4134/4885ALDH1A1 4557/4885 |
| US-20160244435-A1 | EXPANDED THERAPEUTIC POTENTIAL IN NITROHETEROARYL ANTIMICROBIALS | NQO1, TXN2, MPO | CYP2C19 586/4885LMNA 2408/4885ALDH1A1 1589/4885 |
| US-20110251159-A1 | Phosphoramidate Alkylator Prodrugs | TYMP, PAICS, PNP | CYP2C19 2781/4885LMNA 3521/4885ALDH1A1 1961/4885 |
| US-20140031289-A1 | POLY(ORGANOPHOSPHAZENE) CONTAINING DEGRADATION CONTROLLABLE IONIC GROUP, PREPARATION METHOD THEREOF AND USE THEREOF | PHOSPHO1, PLCB3, INPP5D | CYP2C19 140/4885LMNA 3315/4885ALDH1A1 4053/4885 |
| US-20090312276-A1 | Compositions and Methods for Treating Cancer | HIF1A, HIF1AN, EGLN3 | CYP2C19 2246/4885LMNA 2031/4885ALDH1A1 306/4885 |
| US-20080145372-A1 | Bioreductively-Activated Prodrugs | NME2, PNP, NUDT1 | CYP2C19 35/4885LMNA 1716/4885ALDH1A1 219/4885 |
| US-20210238144-A1 | Phenyl Derivatives | TFAM, PC, PCK2 | CYP2C19 2964/4885LMNA 3023/4885ALDH1A1 1185/4885 |
| US-20220048865-A1 | Novel Phenyl Derivatives | TFAM, GOT2, NDUFAB1 | CYP2C19 2968/4885LMNA 3170/4885ALDH1A1 1313/4885 |
| US-20250214944-A1 | Novel Phenyl Derivatives | TFAM, GOT2, NDUFAB1 | CYP2C19 2968/4885LMNA 3170/4885ALDH1A1 1313/4885 |
| US-20200399225-A1 | Novel Phenyl Derivatives | TFAM, GOT2, NDUFAB1 | CYP2C19 2968/4885LMNA 3170/4885ALDH1A1 1313/4885 |
| US-20230365559-A1 | NOVEL AMINOPYRIDINES AND THEIR USE IN TREATING CANCER | DCK, DTYMK, TYMP | CYP2C19 1553/4885LMNA 1848/4885ALDH1A1 1620/4885 |
| US-20190337903-A1 | Novel Phenyl Derivatives | TFAM, GOT2, NDUFAB1 | CYP2C19 2968/4885LMNA 3170/4885ALDH1A1 1313/4885 |
| US-20140170240-A1 | Phosphoramidate Alkylator Prodrugs | TYMP, PAICS, PNP | CYP2C19 2781/4885LMNA 3521/4885ALDH1A1 1961/4885 |
| US-20130303778-A1 | PHOSPHORAMIDATE ALKYLATOR PRODRUGS | TYMP, PAICS, PNP | CYP2C19 2781/4885LMNA 3521/4885ALDH1A1 1961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.