Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A known ✓ | P35499 | 5/20 | 0.42 |
| ▸ | ADRA2A known ✓ | P08913 | 2/20 | 0.39 |
| ▸ | ADRA2B known ✓ | P18089 | 2/20 | 0.39 |
| ▸ | ADRA2C known ✓ | P18825 | 2/20 | 0.39 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.39 |
| ▸ | HTR7 known ✓ | P34969 | 1/20 | 0.39 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B known ✓ | P35368 | 1/20 | 0.39 |
| ▸ | DPP4 known ✓ | P27487 | 2/20 | 0.38 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2232111 | 0.98 | SCN4A (0.43) | SCN4AACP3ADRA2AADRA2BADRA2C | |
| Water SCHEMBL11461116 | 0.96 | SCN4A (0.42) | SCN4AACP3ADRA2AADRA2BADRA2C | |
| Bromide SCHEMBL6122970 | 0.96 | SCN4A (0.42) | SCN4AACP3ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL7646260 | 0.86 | ACP3 (0.47) | SCN4AACP3ADRA2AADRA2BSLC6A2 | |
| SCHEMBL3994648 | 0.84 | ACP3 (0.48) | SCN4AACP3ADRA2AADRA2BSLC6A2 | |
| SCHEMBL20241459 | 0.84 | ACP3 (0.48) | SCN4AACP3ADRA2AADRA2BSLC6A2 | |
| SCHEMBL10580767 | 0.83 | ADRA2A (0.43) | SCN4AADRA2AADRA2BADRA2CSLC6A2 | |
| SCHEMBL16130866 | 0.82 | DPP4 (0.39) | SCN4AADRA2AADRA2CALDH1A1DPP4 | |
| Water SCHEMBL3190745 | 0.81 | DPP4 (0.38) | SCN4AADRA2AADRA2CALDH1A1DPP4 | |
| SCHEMBL8868744 | 0.80 | CYP3A4 (0.37) | SCN4AADRA2AADRA2BADRA2CSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677948-A | High specific gravity transparent resin composition and method for producing particles thereof | 广东热浪新材料科技有限公司 | 2023-02-03 | — | — | CN | claimed |
| EP-2049594-B1 | METHOD OF PREPARING RESIN COMPOSITION FOR ARTIFICIAL MARBLE CHIP HAVING HIGH SPECIFIC GRAVITY AND HIGH INDEX OF REFRACTION | CHEIL IND INC (KR) | 2014-10-08 | — | — | EP | claimed |
| JP-2009544793-A | — | — | 2009-12-17 | — | — | JP | claimed |
| EP-2049594-A1 | METHOD OF PREPARING RESIN COMPOSITION FOR ARTIFICIAL MARBLE CHIP HAVING HIGH SPECIFIC GRAVITY AND HIGH INDEX OF REFRACTION | Cheil Industries Inc. (KR) | 2009-04-22 | — | — | EP | claimed |
| WO-2008013346-A1 | METHOD OF PREPARING RESIN COMPOSITION FOR ARTIFICIAL MARBLE CHIP HAVING HIGH SPECIFIC GRAVITY AND HIGH INDEX OF REFRACTION | CHEIL INDUSTRIES INC. (KR) | 2008-01-31 | — | — | WO | claimed |
| CN-115677948-A | High specific gravity transparent resin composition and method for producing particles thereof | 广东热浪新材料科技有限公司 | 2023-02-03 | — | — | CN | disclosed |
| EP-2152253-B1 | SYNERGISTIC ACTIVE PREPARATIONS COMPRISING 1,2-DECANEDIOL AND FURTHER ANTIMICROBIAL ACTIVE COMPOUNDS | SYMRISE AG (DE) | 2018-04-18 | — | — | EP | disclosed |
| US-20170275202-A1 | COMPOSITIONS COMPRISING CURABLE RESIN FOR ANTI-STATIC FLOORING | ASHLAND LICENSING AND INTELLECTUAL PROPERTY LLC (US) | 2017-09-28 | — | — | US | disclosed |
| EP-3191426-A1 | COMPOSITIONS COMPRISING CURABLE RESIN FOR ANTI-STATIC FLOORING | Ashland Licensing And Intellectual Property, LLC (US) | 2017-07-19 | — | — | EP | disclosed |
| EP-2049594-B1 | METHOD OF PREPARING RESIN COMPOSITION FOR ARTIFICIAL MARBLE CHIP HAVING HIGH SPECIFIC GRAVITY AND HIGH INDEX OF REFRACTION | CHEIL IND INC (KR) | 2014-10-08 | — | — | EP | disclosed |
| US-7981948-B2 | Artificial stone and associated methods | CHEIL INDUSTRIES, INC. (KR) | 2011-07-19 | — | — | US | disclosed |
| US-20100196504-A1 | SYNERGISTIC ACTIVE PREPARATIONS COMPRISING 1,2-DECANEDIOL AND FURTHER ANTIMICROBIAL ACTIVE COMPOUNDS | SYMRISE GMBH & CO. KG (DE) | 2010-08-05 | — | — | US | disclosed |
| EP-0584801-A2 | Aromatic polycarbonate resins and process for the preparation thereof | Mitsubishi Chemical Corporation (JP) | 1994-03-02 | — | — | EP | disclosed |
| US-5286386-A | Treating with solvent, comminuting surfactant and flocculant, separation | ENSR CORPORATION (US) | 1994-02-15 | — | — | US | disclosed |
| US-5154831-A | Contacting oily substrate with water insoluble solvent and surfactant, separating phases | ENSR CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0479258-A1 | Solvent extraction process for treatment of oily substrates | ENSR CORPORATION (US) | 1992-04-08 | — | — | EP | disclosed |
| US-4186111-A | NOBLE METAL IN FORM OF HIGHLY DISPERSED GRAVIMETRIC PRECIPITATE IN COGEL OF ALUMINA-SILICA | CHEVRON RESEARCH COMPANY (US) | 1980-01-29 | — | — | US | disclosed |
| US-4137146-A | Two-stage hydroconversion process (hydrocracking and reforming) using a stabilized aluminosilicate hydrocracking catalyst | CHEVRON RESEARCH COMPANY (US) | 1979-01-30 | — | — | US | disclosed |
| US-4012312-A | CATALYST PREPARED FROM SILICA-ALUMINA GEL AND AN ORGANIC TRANSITION METAL COMPOUND | CHEVRON RESEARCH COMPANY (US) | 1977-03-15 | — | — | US | disclosed |
| US-3978001-A | HYDROREFINING, PALLADIUM ON SIO2-AL2O3 | CHEVRON RESEARCH COMPANY (US) | 1976-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100196504-A1 | SYNERGISTIC ACTIVE PREPARATIONS COMPRISING 1,2-DECANEDIOL AND FURTHER ANTIMICROBIAL ACTIVE COMPOUNDS | DDT, CUTA, DPM1 | SCN4A 3353/4885ADRA2A 1798/4885ADRA2B 1108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.