Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A known ✓ | Q14524 | 3/20 | 0.39 |
| ▸ | SCN9A known ✓ | Q15858 | 3/20 | 0.39 |
| ▸ | S1PR1 known ✓ | P21453 | 1/20 | 0.39 |
| ▸ | SIGMAR1 known ✓ | Q99720 | 1/20 | 0.39 |
| ▸ | HSP90AA1 known ✓ | P07900 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 5/20 | 0.41 |
| ▸ | CNR1 | P21554 | 4/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | EBP | Q15125 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16166619 | 1.00 | CNR2 (0.41) | CNR2CNR1TAAR1SCN5ASCN9A | |
| Hydrochloric Acid SCHEMBL631052 | 1.00 | CNR2 (0.41) | CNR2CNR1TAAR1SCN5ASCN9A | |
| SCHEMBL14938729 | 0.98 | CNR2 (0.42) | CNR2CNR1TAAR1SCN5ASCN9A | |
| SCHEMBL28042786 | 0.98 | CNR2 (0.42) | CNR2CNR1TAAR1SCN5ASCN9A | |
| Bromide SCHEMBL9871488 | 0.96 | CNR2 (0.41) | CNR2CNR1TAAR1SCN5ASCN9A | |
| SCHEMBL9426651 | 0.90 | TAAR1 (0.43) | TAAR1KMT2AKIF11 | |
| Hydrochloric Acid SCHEMBL11757637 | 0.85 | S1PR1 (0.41) | CNR2CNR1SCN5ASCN9AS1PR1 | |
| Hydrochloric Acid SCHEMBL11757673 | 0.85 | S1PR1 (0.41) | CNR2CNR1SCN5ASCN9AS1PR1 | |
| SCHEMBL8644028 | 0.83 | KIF11 (0.52) | TAAR1KIF11 | |
| Hydrochloric Acid SCHEMBL28488727 | 0.83 | SCN5A (0.40) | CNR2CNR1SCN5ASCN9AS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104711877-B | Polyacrylonitrile fibre original position mineralising, water-saving and emission-reducing dyeing post-processing approach and auxiliary agent | 西安工程大学 | 2017-03-15 | — | — | CN | claimed |
| CN-104695253-B | Cellulose fibre mineralising degree of depth water-saving and emission-reducing dyeing post-processing approach and auxiliary agent in situ | 西安工程大学 | 2017-01-04 | — | — | CN | claimed |
| CN-104727172-B | Fypro mineralising degree of depth water-saving and emission-reducing dyeing post-processing approach and auxiliary agent in situ | 西安工程大学 | 2017-01-04 | — | — | CN | claimed |
| CN-104711872-B | Natural protein fibre mineralising water-saving and emission-reducing dyeing post-processing approach and auxiliary agent in situ | 西安工程大学 | 2016-12-07 | — | — | CN | claimed |
| CN-105625050-A | Water-saving dyeing process of wool | JIANGSU NIJIAXIANG GROUP WORSTED TEXTILE CO LTD | 2016-06-01 | — | — | CN | claimed |
| CN-104727172-A | Method and auxiliary agents for polyamide fiber in-situ mineralization deep water-saving and emission-reducing dyeing after-treatment | UNIV XI AN POLYTECHNIC | 2015-06-24 | — | — | CN | claimed |
| CN-104711877-A | In-situ mineralization and water-saving emission-reduction dyeing post-treatment method for polyacrylonitrile fibers and auxiliary agents | UNIV XI AN POLYTECHNIC | 2015-06-17 | — | — | CN | claimed |
| CN-104711872-A | In-situ mineralization and water-saving emission-reduction dyeing post-treatment method for natural protein fibers and auxiliary agents | UNIV XI AN POLYTECHNIC | 2015-06-17 | — | — | CN | claimed |
| CN-104695253-A | Cellulosic fiber in-situ mineralization deep water-saving and emission reduction dyeing aftertreatment method and additive | UNIV XI AN POLYTECHNIC | 2015-06-10 | — | — | CN | claimed |
| EP-3662891-B1 | COMPOSITION FOR PREVENTING HAIR LOSS OR PROMOTING HAIR GROWTH | CK REGEON INC (KR) | 2023-06-07 | — | — | EP | disclosed |
| US-11154566-B2 | Composition for preventing hair loss or promoting hair growth | CK BIOTECH (KR) | 2021-10-26 | — | — | US | disclosed |
| US-20200179425-A1 | COMPOSITION FOR PREVENTING HAIR LOSS OR PROMOTING HAIR GROWTH | CK BIOTECH (KR) | 2020-06-11 | — | — | US | disclosed |
| EP-3662891-A2 | COMPOSITION FOR PREVENTING HAIR LOSS OR PROMOTING HAIR GROWTH | CK Biotech (KR) | 2020-06-10 | — | — | EP | disclosed |
| CN-108977955-A | A kind of preparation method for the composite material that hydrophobicity is strong | 浙江金亿润纺织品有限公司 | 2018-12-11 | — | — | CN | disclosed |
| CN-104695253-A | Cellulosic fiber in-situ mineralization deep water-saving and emission reduction dyeing aftertreatment method and additive | UNIV XI AN POLYTECHNIC | 2015-06-10 | — | — | CN | disclosed |
| CN-104294590-A | Raw-cotton fiber dyeing and finishing auxiliary for processing of colored spun yarns and application of auxiliary | UNIV XI AN POLYTECHNIC | 2015-01-21 | — | — | CN | disclosed |
| EP-2531203-A2 | MENTHA SUAVEOLENS ESSENTIAL OIL AND THERAPEUTIC ACTIVITIES THEREOF | Universita'Degli Studi di Roma "La Sapienza" (IT) | 2012-12-12 | — | — | EP | disclosed |
| US-20120129838-A1 | Composition for Preventing and Treating Alopecia Disorder Containing Morgalanthamine Compounds as an Active Ingredient | THE INDUSTRY & ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY (KR) | 2012-05-24 | — | — | US | disclosed |
| WO-2011092655-A2 | MENTHA SUAVEOLENS ESSENTIAL OIL AND THERAPEUTIC ACTIVITIES THEREOF | UNIVERSITÀ DEGLI STUDI DI ROMA "LA SAPIENZA" (IT) | 2011-08-04 | — | — | WO | disclosed |
| US-5641464-A | Stethoscope cleansing device and method | B & B MEDICAL TECHNOLOGIES, INC. (US) | 1997-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129838-A1 | Composition for Preventing and Treating Alopecia Disorder Containing Morgalanthamine Compounds as an Active Ingredient | MITF, GLA, GALNT3 | SCN5A 1386/4885SCN9A 1110/4885S1PR1 4439/4885 |
| US-11154566-B2 | Composition for preventing hair loss or promoting hair growth | HES1, MKI67, SHBG | SCN5A 2990/4885SCN9A 2605/4885S1PR1 4762/4885 |
| US-20200179425-A1 | COMPOSITION FOR PREVENTING HAIR LOSS OR PROMOTING HAIR GROWTH | HES1, MKI67, SHBG | SCN5A 2990/4885SCN9A 2605/4885S1PR1 4762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.