Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 known ✓ | P03956 | 1/20 | 0.44 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.38 |
| ▸ | HRH3 known ✓ | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29001182 | 0.98 | MMP1 (0.45) | MMP1MMP2MMP3PKMSMN1; SMN2 | |
| SCHEMBL21676282 | 0.83 | ALDH1A1 (0.38) | MMP1MMP2SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL14626185 | 0.83 | MMP1 (0.47) | MMP1MMP2MMP3PKMSMN1; SMN2 | |
| SCHEMBL23479938 | 0.83 | MMP1 (0.47) | MMP1MMP2MMP3PKMSMN1; SMN2 | |
| SCHEMBL14155209 | 0.81 | CTSK (0.50) | MMP1MMP2MMP3PKMSMN1; SMN2 | |
| SCHEMBL11450639 | 0.80 | MMP1 (0.38) | MMP1MMP2MMP3PKMSMN1; SMN2 | |
| SCHEMBL27431828 | 0.79 | CTSK (0.38) | MMP1MMP2MMP3SMN1; SMN2CTSK | |
| SCHEMBL8369048 | 0.78 | — | — | |
| SCHEMBL12487398 | 0.78 | — | — | |
| SCHEMBL8916758 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4382315-A1 | PNEUMATIC TIRE | Sumitomo Rubber Industries, Ltd. (JP) | 2024-06-12 | — | — | EP | disclosed |
| EP-4049855-B1 | TIRE | SUMITOMO RUBBER IND (JP) | 2024-05-29 | — | — | EP | disclosed |
| US-20240123765-A1 | TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2024-04-18 | — | — | US | disclosed |
| US-20240066926-A1 | PNEUMATIC TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2024-02-29 | — | — | US | disclosed |
| US-20240051339-A1 | PNEUMATIC TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2024-02-15 | — | — | US | disclosed |
| US-20240051340-A1 | PNEUMATIC TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2024-02-15 | — | — | US | disclosed |
| US-20240042813-A1 | TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2024-02-08 | — | — | US | disclosed |
| US-20230416507-A1 | TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2023-12-28 | — | — | US | disclosed |
| US-20230415516-A1 | TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2023-12-28 | — | — | US | disclosed |
| US-20230416508-A1 | TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2023-12-28 | — | — | US | disclosed |
| US-20220212501-A1 | PNEUMATIC TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2022-07-07 | — | — | US | disclosed |
| US-20220212504-A1 | PNEUMATIC TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2022-07-07 | — | — | US | disclosed |
| US-20220212502-A1 | PNEUMATIC TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2022-07-07 | — | — | US | disclosed |
| EP-4023462-A1 | PNEUMATIC TIRE | Sumitomo Rubber Industries, Ltd. (JP) | 2022-07-06 | — | — | EP | disclosed |
| EP-4023463-A1 | PNEUMATIC TIRE | Sumitomo Rubber Industries, Ltd. (JP) | 2022-07-06 | — | — | EP | disclosed |
| WO-2022045078-A1 | PNEUMATIC TIRE | 住友ゴム工業株式会社 | 2022-03-03 | — | — | WO | disclosed |
| WO-2021215092-A1 | TIRE CORD AND TIRE | 住友ゴム工業株式会社 (JP) | 2021-10-28 | — | — | WO | disclosed |
| WO-2021153415-A1 | MODIFIED NATURAL RUBBER AND RUBBER COMPOSITION | 住友ゴム工業株式会社 | 2021-08-05 | — | — | WO | disclosed |
| WO-2021111693-A1 | TIRE | 住友ゴム工業株式会社 | 2021-06-10 | — | — | WO | disclosed |
| WO-2021075256-A1 | TIRE | 住友ゴム工業株式会社 | 2021-04-22 | — | — | WO | disclosed |