Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Tyrosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 3/20 | 0.68 |
| ▸ | EGFR known ✓ | P00533 | 1/20 | 0.62 |
| ▸ | LCK known ✓ | P06239 | 1/20 | 0.62 |
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.62 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.62 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.54 |
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.54 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.54 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.54 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.54 |
| ▸ | DRD3 known ✓ | P35462 | 1/20 | 0.54 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.54 |
| ▸ | KCNH2 known ✓ | Q12809 | 1/20 | 0.54 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.96 |
| ▸ | ALPI | P09923 | 1/20 | 0.68 |
| ▸ | PKM | P14618 | 1/20 | 0.68 |
| ▸ | XIAP | P98170 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyrosine SCHEMBL246905 | 1.00 | SLC7A5 (0.96) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL28428764 | 1.00 | SLC7A5 (0.96) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL16893973 | 1.00 | SLC7A5 (0.96) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL16893972 | 1.00 | SLC7A5 (0.96) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL6488392 | 1.00 | SLC7A5 (0.96) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL28820995 | 1.00 | SLC7A5 (0.96) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL11195244 | 0.98 | SLC7A5 (0.92) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL20240404 | 0.98 | SLC7A5 (0.92) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL1581 | 0.98 | SLC7A5 (1.00) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL1580 | 0.98 | SLC7A5 (1.00) | SLC7A5PTGS1ALPIPKMXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119867276-A | Live bacteria soup ladle, preparation method and application thereof | 广州弘海材料科技有限公司 | 2025-04-25 | — | — | CN | claimed |
| CN-119867277-A | Prebiotic steamed stuffed bun, preparation method and application thereof | 广州弘海材料科技有限公司 | 2025-04-25 | — | — | CN | claimed |
| CN-118844578-A | Meat seasoning packet and sauce seasoning packet combined type prefabricated vegetable and preparation method and application thereof | 广州弘海材料科技有限公司 | 2024-10-29 | — | — | CN | claimed |
| CN-118844584-A | Prefabricated dish and preparation method and application thereof | 广州弘海材料科技有限公司 | 2024-10-29 | — | — | CN | claimed |
| CN-115957381-A | Injectable sericin hydrogel for regulating bone immune microenvironment | 复旦大学附属中山医院 | 2023-04-14 | — | — | CN | claimed |
| CN-114314666-B | Oxygen vacancy type nano molybdenum trioxide antibacterial agent and preparation method thereof | 中国科学院地球环境研究所 | 2023-04-07 | — | — | CN | claimed |
| CN-115926200-A | Preparation method and application of enzyme-catalyzed double-crosslinked polymer composite hydrogel material | 河南师范大学 | 2023-04-07 | — | — | CN | claimed |
| CN-114907760-A | Preparation method of multifunctional coating based on polyurethane | 西南交通大学 | 2022-08-16 | — | — | CN | claimed |
| CN-114314666-A | Oxygen vacancy type nano molybdenum trioxide antibacterial agent and preparation method thereof | 中国科学院地球环境研究所 | 2022-04-12 | — | — | CN | claimed |
| CN-114173578-A | Compositions and methods for treating cancer | 迪美公司 | 2022-03-11 | — | — | CN | claimed |
| CN-107081131-A | Ferroferric oxide magnetic nano sorbing material that a kind of tyrosine is modified and its preparation method and application | 天津理工大学 | 2017-08-22 | — | — | CN | claimed |
| EP-3060200-A1 | TYROSINE DERIVATIVES AND COMPOSITIONS COMPRISING THEM | Tyme, Inc. (US) | 2016-08-31 | — | — | EP | claimed |
| US-20150197483-A1 | METHODS AND COMPOSITIONS FOR MAKING AN AMINO ACID TRIHYDROCHLORIDE | WARSAW ORTHOPEDIC, INC. (US) | 2015-07-16 | — | — | US | claimed |
| WO-2015061288-A1 | TYROSINE DERIVATIVES AND COMPOSITIONS COMPRISING THEM | TYME, INC. (US) | 2015-04-30 | — | — | WO | claimed |
| CN-104274412-A | Pharmaceutical preparation containing temozolomide, pharmaceutically acceptable salts or other derivatives thereof | BEIJING HENGRUI KANGDA PHARMACEUTICAL SCI & TECH DEV CO LTD | 2015-01-14 | — | — | CN | claimed |
| CN-102512672-B | Artemisia pollen allergen vaccine and preparation method thereof | BEIJING XINHUALIAN XIEHE PHARMACEUTICAL CO LTD | 2014-09-10 | — | — | CN | claimed |
| WO-2009046738-A1 | COMPOSITION FOR TREATING LUNG CANCER, PARTICULARLY OF NON-SMALL LUNG CANCERS (NSCLC) | CUREVAC GMBH (DE) | 2009-04-16 | — | — | WO | claimed |
| EP-0380940-B1 | Aqueous skin tanning composition | SCHREUDER CHEM ADVIESBUREAU (NL) | 1994-10-05 | — | — | EP | claimed |
| EP-0380940-A1 | Aqueous skin tanning composition | Chemisch Adviesbureau Drs. J.C.P. Schreuder B.V. (NL) | 1990-08-08 | — | — | EP | claimed |
| US-4496703-A | Process for recovering amino acids from protein hydrolysates | SOCIETE D'ASSISTANCE TECHNIQUE POUR PRODUITS NESTLE S.A. (CH) | 1985-01-29 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150197483-A1 | METHODS AND COMPOSITIONS FOR MAKING AN AMINO ACID TRIHYDROCHLORIDE | ALKBH3, AADAT, ALKBH1 | PTGS1 2378/4885EGFR 126/4885LCK 289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.