Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B known ✓ | Q00975 | 1/20 | 0.41 |
| ▸ | HRH3 known ✓ | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ERN1 | O75460 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7001155 | 0.98 | MAPT (0.42) | MAPTCACNA1BAPBA1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28852389 | 0.89 | DDAH1 (0.39) | MAPTCACNA1BAPBA1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28713623 | 0.87 | DDAH1 (0.45) | MAPTCACNA1BAPBA1ERN1HRH4 | |
| SCHEMBL28255342 | 0.87 | ACHE (0.40) | MAPTCACNA1BAPBA1MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL1276411 | 0.87 | CASP1 (0.36) | MAPTCACNA1BAPBA1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2525927 | 0.86 | PAOX (0.46) | ERN1ACHE | |
| SCHEMBL13055388 | 0.86 | MAPT (0.42) | MAPTCACNA1BAPBA1MEN1KMT2A | |
| SCHEMBL1276392 | 0.85 | DDAH1 (0.46) | MAPTCACNA1BAPBA1MEN1KMT2A | |
| SCHEMBL20207166 | 0.84 | PAOX (0.47) | MAPTCACNA1BAPBA1ERN1TSHR | |
| SCHEMBL6951293 | 0.84 | PAOX (0.47) | MAPTCACNA1BAPBA1ERN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4077485-B1 | CROSSLINKABLE REACTIVE SILICONE ORGANIC COPOLYMERS DISPERSIONS | WACKER CHEMIE AG (DE) | 2023-05-17 | — | — | EP | claimed |
| US-20220372195-A1 | CROSSLINKABLE REACTIVE SILICONE ORGANIC COPOLYMERS DISPERSIONS | WACKER CHEMIE AG (DE) | 2022-11-24 | — | — | US | claimed |
| EP-4077485-A1 | CROSSLINKABLE REACTIVE SILICONE ORGANIC COPOLYMERS DISPERSIONS | Wacker Chemie AG (DE) | 2022-10-26 | — | — | EP | claimed |
| CN-114829456-A | Crosslinkable reactive silicone organic copolymer dispersions | 瓦克化学股份公司 | 2022-07-29 | — | — | CN | claimed |
| WO-2021126174-A1 | CROSSLINKABLE REACTIVE SILICONE ORGANIC COPOLYMERS DISPERSIONS | WACKER CHEMIE AG (DE) | 2021-06-24 | — | — | WO | claimed |
| US-9850327-B2 | Use of modified water-soluble polymers as crosslinking auxiliary agents | WACKER CHEMIE AG (DE) | 2017-12-26 | — | — | US | claimed |
| EP-3049450-B1 | USE OF MODIFIED WATER-SOLUBLE POLYMERS AS CROSSLINKING AUXILIARY AGENTS | WACKER CHEMIE AG (DE) | 2017-11-08 | — | — | EP | claimed |
| US-20160208031-A1 | USE OF MODIFIED WATER-SOLUBLE POLYMERS AS CROSSLINKING AUXILIARY AGENTS | WACKER CHEMIE AG (DE) | 2016-07-21 | — | — | US | claimed |
| US-8637613-B2 | Self-dispersible silicone copolymers and method for the production and use thereof | WACKER CHEMIE AG (DE) | 2014-01-28 | — | — | US | claimed |
| US-20100041822-A1 | CROSSLINKABLE REACTIVE SILICONE ORGANIC COPOLYMERS AND METHOD FOR THE PRODUCTION AND USE THEREOF | WACKER CHEMIE AG (DE) | 2010-02-18 | — | — | US | claimed |
| WO-2025133027-A1 | PROCESS FOR FORMING A COATING COMPOSITION, A COATING COMPOSITION, AND AN ARTICLE COMPRISING THE SAME | WACKER CHEMIE AG (DE) | 2025-06-26 | — | — | WO | disclosed |
| CN-115245589-B | Novel degradable embolism microsphere with controllable particle size and preparation method thereof | 苏州浩微生物医疗科技有限公司 | 2024-08-20 | — | — | CN | disclosed |
| CN-115245591-B | Degradable embolism microsphere and preparation method thereof | 苏州浩微生物医疗科技有限公司 | 2024-06-14 | — | — | CN | disclosed |
| EP-4077485-B1 | CROSSLINKABLE REACTIVE SILICONE ORGANIC COPOLYMERS DISPERSIONS | WACKER CHEMIE AG (DE) | 2023-05-17 | — | — | EP | disclosed |
| CN-114829456-B | Crosslinkable reactive silicone organic copolymer dispersions | 瓦克化学股份公司 | 2023-04-28 | — | — | CN | disclosed |
| US-20110257297-A1 | Graft Copolymers and Use Thereof as Low-Profile Additives | WACKER CHEMIE AG (DE) | 2011-10-20 | — | — | US | disclosed |
| US-20100273934-A1 | CROSSLINKABLE VINYL ESTER COPOLYMERS AND THEIR USE AS LOW-PROFILE ADDITIVES | WACKER CHEMIE AG (DE) | 2010-10-28 | — | — | US | disclosed |
| US-20100227995-A1 | PRODUCTION OF VINYL ACETATE - VINYL ESTER COPOLYMERS HAVING A LOW CONTENT OF HIGH-BOILING VINYL ESTERS | WACKER CHEMIE AG (DE) | 2010-09-09 | — | — | US | disclosed |
| US-20100041822-A1 | CROSSLINKABLE REACTIVE SILICONE ORGANIC COPOLYMERS AND METHOD FOR THE PRODUCTION AND USE THEREOF | WACKER CHEMIE AG (DE) | 2010-02-18 | — | — | US | disclosed |
| US-20100010165-A1 | SELF-DISPERSIBLE SILICONE COPOLYMERS AND METHOD FOR THE PRODUCTION AND USE THEREOF | WACKER CHEMIE AG (DE) | 2010-01-14 | — | — | US | disclosed |