Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 5/20 | 0.54 |
| ▸ | GAA known ✓ | P10253 | 7/20 | 0.52 |
| ▸ | HSP90AA1 known ✓ | P07900 | 1/20 | 0.48 |
| ▸ | MAOB known ✓ | P27338 | 1/20 | 0.41 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 7/20 | 0.54 |
| ▸ | CA12 | O43570 | 5/20 | 0.54 |
| ▸ | CA9 | Q16790 | 5/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.54 |
| ▸ | CA1 | P00915 | 4/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | CA7 | P43166 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31310809 | 1.00 | ALDH1A1 (0.54) | ALDH1A1HSD17B10ALOX15CA12CA2 | |
| SCHEMBL64970 | 0.97 | — | — | |
| Bromide SCHEMBL11510703 | 0.94 | ALDH1A1 (0.54) | ALDH1A1HSD17B10ALOX15CA12CA2 | |
| Water SCHEMBL11319775 | 0.94 | ALDH1A1 (0.54) | ALDH1A1HSD17B10ALOX15CA12CA2 | |
| SCHEMBL28599140 | 0.87 | ALDH1A1 (0.48) | ALDH1A1HSD17B10ALOX15CA12CA2 | |
| Methoxymethane SCHEMBL9478417 | 0.87 | ALDH1A1 (0.57) | ALDH1A1HSD17B10ALOX15CA12CA2 | |
| SCHEMBL10481889 | 0.85 | ALDH1A1 (0.52) | ALDH1A1HSD17B10ALOX15CA12CA2 | |
| Ether SCHEMBL9342203 | 0.80 | ALDH1A1 (0.47) | ALDH1A1HSD17B10ALOX15CA12CA2 | |
| SCHEMBL9763212 | 0.80 | ALDH1A1 (0.69) | ALDH1A1HSD17B10ALOX15CA12CA2 | |
| Hydrochloric Acid SCHEMBL10954400 | 0.80 | CA14 (0.56) | ALDH1A1HSD17B10ALOX15CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119125117-A | Nitric oxide detection kit with good stability and preparation method thereof | 安徽伊普诺康生物技术股份有限公司 | 2024-12-13 | — | — | CN | claimed |
| CN-119125117-A | Nitric oxide detection kit with good stability and preparation method thereof | 安徽伊普诺康生物技术股份有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-119125117-A | Nitric oxide detection kit with good stability and preparation method thereof | 安徽伊普诺康生物技术股份有限公司 | 2024-12-13 | — | — | CN | disclosed |
| US-12083108-B2 | Compounds for targeting mutant huntingtin protein and uses thereof | CHDI FOUNDATION, INC. (US) | 2024-09-10 | — | — | US | disclosed |
| CN-112625442-B | Cyanate resin composition, prepreg, laminate and printed circuit board | 广东盈骅新材料科技有限公司 | 2023-08-22 | — | — | CN | disclosed |
| US-20220409600-A1 | COMPOUNDS FOR TARGETING MUTANT HUNTINGTIN PROTEIN AND USES THEREOF | CHDI FOUNDATION, INC. | 2022-12-29 | — | — | US | disclosed |
| US-11389438-B2 | Compounds for targeting mutant huntingtin protein and uses thereof | CHDI FOUNDATION, INC. (US) | 2022-07-19 | — | — | US | disclosed |
| CN-112625442-A | Cyanate ester resin composition, prepreg, laminate and printed wiring board | 广东盈骅新材料科技有限公司 | 2021-04-09 | — | — | CN | disclosed |
| US-20200276176-A1 | COMPOUNDS FOR TARGETING MUTANT HUNTINGTIN PROTEIN AND USES THEREOF | CHDI FOUNDATION, INC. | 2020-09-03 | — | — | US | disclosed |
| CN-110198700-A | Compositions comprising resorcinol or derivatives thereof | 莱雅公司 | 2019-09-03 | — | — | CN | disclosed |
| EP-0124877-B1 | COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIALS | FUJI PHOTO FILM CO., LTD. (JP) | 1988-04-13 | — | — | EP | disclosed |
| US-4732845-A | COLORLESS PHENOLIC AMIDE | FUJI PHOTO FILM CO., LTD. (JP) | 1988-03-22 | — | — | US | disclosed |
| US-4584264-A | POLYHYDROXYAROMATIC SULFONAMIDE AS STAIN INHIBITOR | FUJI PHOTO FILM CO., LTD. (JP) | 1986-04-22 | — | — | US | disclosed |
| US-4547452-A | Color diffusion transfer photographic element with sufinic acid | FUJI PHOTO FILM CO., LTD. (JP) | 1985-10-15 | — | — | US | disclosed |
| US-4511643-A | STYRENESULFINATE POLYMER | FUJI PHOTO FILM CO., LTD. (JP) | 1985-04-16 | — | — | US | disclosed |
| EP-0124877-A2 | Color photographic light-sensitive materials | FUJI PHOTO FILM CO., LTD. (JP) | 1984-11-14 | — | — | EP | disclosed |
| US-4198239-A | ACYLAMINO SUBSTITUTED HYDROQUINONES | AGFA-GEVAERT, A.G. (DE) | 1980-04-15 | — | — | US | disclosed |
| US-4124393-A | PHOTOGRAPHY | FUJI PHOTO FILM CO., LTD. (JP) | 1978-11-07 | — | — | US | disclosed |
| US-4032349-A | STAIN FREE, COLOR SEPARATIONS | FUJI PHOTO FILM CO., LTD. (JA) | 1977-06-28 | — | — | US | disclosed |
| US-3982946-A | Bis-azo pyrazolone type dye developer and light-sensitive material | FUJI PHOTO FILM CO., LTD. (JA) | 1976-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12083108-B2 | Compounds for targeting mutant huntingtin protein and uses thereof | HTT, HYPK, UBQLN2 | CA2 4736/4885GAA 197/4885HSP90AA1 87/4885 |
| US-11389438-B2 | Compounds for targeting mutant huntingtin protein and uses thereof | HTT, HYPK, UBQLN2 | CA2 4736/4885GAA 197/4885HSP90AA1 87/4885 |
| US-20200276176-A1 | COMPOUNDS FOR TARGETING MUTANT HUNTINGTIN PROTEIN AND USES THEREOF | HTT, HYPK, UBQLN2 | CA2 4736/4885GAA 197/4885HSP90AA1 87/4885 |
| US-20220409600-A1 | COMPOUNDS FOR TARGETING MUTANT HUNTINGTIN PROTEIN AND USES THEREOF | HTT, HYPK, UBQLN2 | CA2 4736/4885GAA 197/4885HSP90AA1 87/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.