Hydrochloric Acid

Hydrochloric Acid

SCHEMBL2747672

CCCCCCCCCCC(CCCCCCCCCC)NCCC[Si](OC)(OC)OC.Cl

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SIGMAR1 known ✓ Q99720 5/20 0.34
LMNA P02545 1/20 0.45
ZDHHC7 Q9NXF8 1/20 0.34
EPHX1 P07099 3/20 0.33
SLC2A1 P11166 1/20 0.33
PLA2G2A P14555 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9702003 1.00 LMNA (0.45) LMNAZDHHC7SIGMAR1EPHX1SLC2A1
Hydrochloric Acid SCHEMBL10389451 1.00 LMNA (0.45) LMNAZDHHC7SIGMAR1EPHX1SLC2A1
SCHEMBL1123235 0.98 LMNA (0.46) LMNAZDHHC7SIGMAR1EPHX1SLC2A1
SCHEMBL23754206 0.88 LMNA (0.39) LMNASIGMAR1
Hydrochloric Acid SCHEMBL23754229 0.85 LMNA (0.44) LMNAZDHHC7EPHX1SLC2A1
SCHEMBL1929523 0.83 LMNA (0.43) LMNAZDHHC7EPHX1SLC2A1
Cyanamide SCHEMBL18335593 0.83 LMNA (0.35) LMNA
SCHEMBL17114245 0.83 LMNA (0.38) LMNAZDHHC7SIGMAR1EPHX1
SCHEMBL28823234 0.82 LMNA (0.47) LMNAZDHHC7EPHX1PLA2G2A
SCHEMBL25206254 0.81 LMNA (0.36) LMNASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11130908-B2 Coated proppants and nanites and methods of making and use of coated proppants and nanites GROUP HOLDINGS, LLC (US) 2021-09-28 US claimed
US-10196559-B1 Coated proppants and nanites and methods of making and use of coated proppants and nanites GROUP HOLDINGS, LLC (US) 2019-02-05 US claimed
US-20180028952-A1 Ballast Water Treatment Systems PETERSON II WILLIAM R (US) 2018-02-01 US claimed
US-20180008920-A1 Ballast Water Treatment Systems Nano Global Corp. (US) 2018-01-11 US claimed
US-9764264-B2 Ballast water treatment systems BERMAN, RENEE 2017-09-19 US claimed
US-20160287717-A1 Core and Surface Modification of Mesoporous Silica Nanoparticles to Achieve Cell Specific Targeting In Vivo. STC UNM (US) 2016-10-06 US claimed
EP-3046547-A1 CORE AND SURFACE MODIFICATION OF MESOPOROUS SILICA NANOPARTICLES TO ACHIEVE CELL SPECIFIC TARGETING IN VIVO STC.UNM (US) 2016-07-27 EP claimed
WO-2016029185-A1 BALLAST WATER TREATMENT SYSTEMS COATING SYSTEMS LABORATORIES, INC. (US) 2016-02-25 WO claimed
US-20150360155-A1 Ballast Water Treatment Systems BERMAN, RENEE 2015-12-17 US claimed
WO-2015042268-A1 CORE AND SURFACE MODIFICATION OF MESOPOROUS SILICA NANOPARTICLES TO ACHIEVE CELL SPECIFIC TARGETING IN VIVO STC.UNM (US) 2015-03-26 WO claimed
US-8178119-B2 Zinc pyrithione, triclosan, polymeric binder, fluorocarbon hydrophobicizing agent; against colonization by house dust mites; mattress ticking, furniture covering fabrics and carpets SANITIZED AG (CH) 2012-05-15 US claimed
US-20080260860-A1 Method for the Acaricidal Finishing of Textile Materials SANITIZED AG (CH) 2008-10-23 US claimed
US-20250304605-A1 ANTIMICROBIAL ORGANOSILANES TOPIKOS SCIENTIFIC, INC. (US) 2025-10-02 US disclosed
US-12264170-B2 Antimicrobial organosilanes TOPIKOS SCIENTIFIC, INC. (US) 2025-04-01 US disclosed
US-12134628-B2 Antimicrobial organosilanes TOPIKOS SCIENTIFIC, INC. 2024-11-05 US disclosed
US-20240309026-A1 ANTIMICROBIAL ORGANOSILANES TOPIKOS SCIENTIFIC, INC. (US) 2024-09-19 US disclosed
US-4845256-A Production of silyl quaternary ammonium compounds SANITIZED AG (CH) 1989-07-04 US disclosed
EP-0108853-B1 3-(TRIMETHOXYSILYL)PROPYLDIDECYLMETHYL AMMONIUM SALTS AND METHOD OF INHIBITING GROWTH OF MICROORGANISMS THEREWITH Klein, Stewart E. (US) 1986-02-26 EP disclosed
EP-0108853-A1 3-(Trimethoxysilyl)propyldidecylmethyl ammonium salts and method of inhibiting growth of microorganisms therewith Klein, Stewart E. (US) 1984-05-23 EP disclosed
US-4394378-A BACTERICIDES, FUNGICIDES CARAGEST/A.G. (CH) 1983-07-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304605-A1 ANTIMICROBIAL ORGANOSILANES ARG1, ACMSD, AAAS SIGMAR1 1107/4885LMNA 4596/4885ZDHHC7 3392/4885
US-12264170-B2 Antimicrobial organosilanes ARG1, ACMSD, AAAS SIGMAR1 1107/4885LMNA 4596/4885ZDHHC7 3392/4885
US-20240309026-A1 ANTIMICROBIAL ORGANOSILANES ARG1, ACMSD, AAAS SIGMAR1 1107/4885LMNA 4596/4885ZDHHC7 3392/4885
US-12134628-B2 Antimicrobial organosilanes ARG1, ACMSD, AAAS SIGMAR1 1107/4885LMNA 4596/4885ZDHHC7 3392/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.