Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Benzoin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC known ✓ | P12931 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 4/20 | 0.95 |
| ▸ | LMNA | P02545 | 3/20 | 0.95 |
| ▸ | CES1 | P23141 | 3/20 | 0.95 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoin SCHEMBL10812569 | 0.98 | CES2 (0.91) | CES2LMNACES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL29017597 | 0.98 | CES2 (0.91) | CES2LMNACES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL145 | 0.98 | CES2 (1.00) | CES2LMNACES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL27696284 | 0.98 | CES2 (1.00) | CES2LMNACES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL28120851 | 0.98 | CES2 (1.00) | CES2LMNACES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL901258 | 0.98 | CES2 (1.00) | CES2LMNACES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL2025536 | 0.98 | CES2 (1.00) | CES2LMNACES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL5833429 | 0.98 | CES2 (1.00) | CES2LMNACES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL10665271 | 0.98 | CES2 (1.00) | CES2LMNACES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL11590328 | 0.95 | CES2 (0.95) | CES2LMNACES1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108400379-B | Preparation method of high-safety lithium ion battery diaphragm and preparation of full battery | 北京大学 | 2020-04-03 | — | — | CN | claimed |
| CN-122018258-A | Electrophotographic photoreceptor, process cartridge, and image forming apparatus | 富士胶片商业创新有限公司 | 2026-05-12 | — | — | CN | disclosed |
| CN-122018268-A | Image forming apparatus having a plurality of image forming units | 富士胶片商业创新有限公司 | 2026-05-12 | — | — | CN | disclosed |
| CN-122018260-A | Electrophotographic photoreceptor, process cartridge, and image forming apparatus | 富士胶片商业创新有限公司 | 2026-05-12 | — | — | CN | disclosed |
| CN-122018262-A | Electrophotographic photoreceptor, process cartridge, and image forming apparatus | 富士胶片商业创新有限公司 | 2026-05-12 | — | — | CN | disclosed |
| CN-122018261-A | Electrophotographic photoreceptor, process cartridge, and image forming apparatus | 富士胶片商业创新有限公司 | 2026-05-12 | — | — | CN | disclosed |
| CN-119717420-A | Electrophotographic photoreceptor, process cartridge, and image forming apparatus | 富士胶片商业创新有限公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-119668059-A | Electrophotographic photoreceptor, process cartridge, and image forming apparatus | 富士胶片商业创新有限公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-119668057-A | Electrophotographic photoreceptor, process cartridge, and image forming apparatus | 富士胶片商业创新有限公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-119126512-A | Electrophotographic photoreceptor, process cartridge, and image forming apparatus | 富士胶片商业创新有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-116736653-A | Electrophotographic photoreceptor, process cartridge, and image forming apparatus | 富士胶片商业创新有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-116719212-A | Electrophotographic photoreceptor, process cartridge, and image forming apparatus | 富士胶片商业创新有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-116627007-A | Electrophotographic photoreceptor, process cartridge, and image forming apparatus | 富士胶片商业创新有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-116627008-A | Image forming unit and image forming apparatus | 富士胶片商业创新有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-116266037-A | Electrophotographic photoreceptor, process cartridge, and image forming apparatus | 富士胶片商业创新有限公司 | 2023-06-20 | — | — | CN | disclosed |
| CN-115857291-A | Electrophotographic photoreceptor, process cartridge, and image forming apparatus | 富士胶片商业创新有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-101291669-B | Use of azabicyclo hexane derivatives | GLAXO GROUP LTD | 2012-09-26 | — | — | CN | disclosed |
| CN-1946714-B | Azabicyclo (3.1.0) hexane derivatives useful as modulators of dopamine d3 receptors | GLAXO GROUP LTD | 2011-06-15 | — | — | CN | disclosed |
| CN-101291669-A | Use of azabicyclo hexane derivatives | GLAXO GROUP LTD (GB) | 2008-10-22 | — | — | CN | disclosed |
| CN-1946714-A | Azabicyclo (3.1.0) hexane derivatives useful as modulators of dopamine d3 receptors | GLAXO GROUP LTD (GB) | 2007-04-11 | — | — | CN | disclosed |