Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 8/20 | 0.57 |
| ▸ | ADRB1 known ✓ | P08588 | 8/20 | 0.57 |
| ▸ | ADRB3 known ✓ | P13945 | 4/20 | 0.57 |
| ▸ | SIGMAR1 known ✓ | Q99720 | 4/20 | 0.56 |
| ▸ | HTR2A known ✓ | P28223 | 3/20 | 0.56 |
| ▸ | HTR2C known ✓ | P28335 | 3/20 | 0.56 |
| ▸ | HTR6 known ✓ | P50406 | 3/20 | 0.56 |
| ▸ | HTR1A known ✓ | P08908 | 3/20 | 0.56 |
| ▸ | SLC6A4 known ✓ | P31645 | 3/20 | 0.54 |
| ▸ | HTR2B known ✓ | P41595 | 3/20 | 0.54 |
| ▸ | SCN1A known ✓ | P35498 | 2/20 | 0.54 |
| ▸ | SCN2A known ✓ | Q99250 | 2/20 | 0.54 |
| ▸ | SCN3A known ✓ | Q9NY46 | 2/20 | 0.54 |
| ▸ | ADRA2A known ✓ | P08913 | 2/20 | 0.54 |
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.54 |
| ▸ | OPRM1 known ✓ | P35372 | 2/20 | 0.54 |
| ▸ | DRD3 known ✓ | P35462 | 2/20 | 0.54 |
| ▸ | HTR1B known ✓ | P28222 | 1/20 | 0.54 |
| ▸ | ADRA2C known ✓ | P18825 | 1/20 | 0.54 |
| ▸ | AGTR1 known ✓ | P30556 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20553006 | 0.99 | ADRB2 (0.59) | ADRB2ADRB1ADRB3SIGMAR1ALDH1A1 | |
| SCHEMBL11719183 | 0.88 | ADRB2 (0.63) | ADRB2ADRB1ADRB3SIGMAR1ALDH1A1 | |
| SCHEMBL11357639 | 0.86 | ADRB2 (0.54) | ADRB2ADRB1ADRB3SIGMAR1ALDH1A1 | |
| SCHEMBL11128346 | 0.82 | CYP1A2 (0.54) | ALDH1A1LMNATSHRMAPK1SMN1; SMN2 | |
| SCHEMBL11128344 | 0.82 | CYP1A2 (0.54) | ALDH1A1LMNATSHRMAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11187323 | 0.81 | L3MBTL1 (0.73) | ADRB2ADRB1ADRB3SIGMAR1ALDH1A1 | |
| SCHEMBL11311157 | 0.81 | ACHE (0.54) | ADRB2ADRB1ADRB3ALDH1A1HTR2A | |
| SCHEMBL11194254 | 0.80 | L3MBTL1 (0.71) | ADRB2ADRB1ADRB3ALDH1A1KDM4E | |
| SCHEMBL11857001 | 0.79 | ADRB2 (0.69) | ADRB2ADRB1ADRB3SIGMAR1ALDH1A1 | |
| SCHEMBL28689787 | 0.79 | CYP2D6 (0.65) | ADRB2ADRB1ADRB3SIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4580752-A1 | TREATMENTS FOR PRURIGO NODULARIS | Galderma Holding SA (CH) | 2025-07-09 | — | — | EP | disclosed |
| CN-118041308-B | Crystal oscillator circuit and clock signal generation method | 珠海市杰理科技股份有限公司 | 2025-05-13 | — | — | CN | disclosed |
| CN-116333215-B | Preparation method and application of Nd (III) surface imprinted polymer with magnetic core-shell structure | 昆明学院 | 2025-04-11 | — | — | CN | disclosed |
| CN-119236102-A | Andrographolide molecularly imprinted recessive drug carrier and preparation method thereof | 南华大学 | 2025-01-03 | — | — | CN | disclosed |
| CN-119219869-A | Deep eutectic-based magnetic molecularly imprinted polymer and preparation method and application thereof | 齐齐哈尔医学院 | 2024-12-31 | — | — | CN | disclosed |
| CN-115254049-B | Preparation method and application of green magnetic dual-template molecularly imprinted polymer | 内蒙古大学 | 2024-06-07 | — | — | CN | disclosed |
| CN-116371466-B | Molecularly imprinted polymer modified magnetic immobilized tryptophan catalyst and preparation method and application thereof | 西安交通大学 | 2024-06-07 | — | — | CN | disclosed |
| CN-118041308-A | Crystal oscillator circuit and clock signal generation method | 珠海市杰理科技股份有限公司 | 2024-05-14 | — | — | CN | disclosed |
| WO-2024047497-A1 | TREATMENTS FOR PRURIGO NODULARIS | Galderma Holding SA (CH) | 2024-03-07 | — | — | WO | disclosed |
| EP-4326938-A1 | METHOD FOR COATING TEXTILE MATERIALS | Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) | 2024-02-28 | — | — | EP | disclosed |
| CN-115926046-A | Catalpol magnetic surface molecularly imprinted polymer and preparation method and application thereof | 吉林大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-112275267-B | Magnetic molecularly imprinted polymer material and application thereof in electrochemical detection of catechin | 中国农业科学院麻类研究所 | 2023-03-28 | — | — | CN | disclosed |
| CN-115368498-A | Preparation method and application of eutectic solvent type molecularly imprinted polymer based on magnetic metal organic framework material carrier | 河南师范大学 | 2022-11-22 | — | — | CN | disclosed |
| CN-110665477-B | Method for preparing molecularly imprinted polymer | 中国农业科学院农业质量标准与检测技术研究所 | 2022-11-22 | — | — | CN | disclosed |
| WO-2022223934-A1 | METHOD FOR COATING TEXTILE MATERIALS | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2022-10-27 | — | — | WO | disclosed |
| CN-114950394-A | Preparation method of magnetic surface molecularly imprinted nano material for selective adsorption separation of diethylstilbestrol | 江苏大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-113512072-B | Metal iridium (III) complex and preparation method and application thereof | 广州市第一人民医院（广州消化疾病中心、广州医科大学附属市一人民医院、华南理工大学附属第二医院） | 2022-07-01 | — | — | CN | disclosed |
| CN-113000035-B | Cerium ion imprinted magnetic nano material and preparation method and application thereof | 南京大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-113072659-B | Sulfadimidine mesoporous molecularly imprinted polymer and preparation method and application thereof | 华南农业大学 | 2022-05-10 | — | — | CN | disclosed |
| CN-114113055-A | Method for detecting norfloxacin based on colorimetric chemical sensing technology | 湖南农业大学 | 2022-03-01 | — | — | CN | disclosed |