SCHEMBL29402893

SCHEMBL29402893

CCC(C)C(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C1CCCN1C(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(NC(=O)C(C)NC(=O)C(CC(N)=O)NC(=O)C(CO)NC(=O)CNC(=O)CNC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CO)NC(=O)C1CCC(=O)N1)C(C)O)C(=O)NC(CC(C)C)C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ HCRTR1 O43613 1/20 0.68
▸ HCRTR2 O43614 1/20 0.68
▸ NPY2R P49146 8/20 0.61
▸ NPY4R P50391 8/20 0.61
▸ NPY5R Q15761 8/20 0.61
▸ NPY1R P25929 6/20 0.61
▸ CALCR P30988 5/20 0.59
▸ NTSR1 P30989 1/20 0.58
▸ RAMP3 O60896 1/20 0.57
▸ F2 P00734 1/20 0.56
▸ OPRM1 P35372 2/20 0.56
▸ OPRD1 P41143 2/20 0.56
▸ OPRK1 P41145 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Neurotensin SCHEMBL30483709 0.87 KDM1A (0.61) NPY2RNPY4RNPY5RNPY1RNTSR1
SCHEMBL30957024 0.87 KDM1A (0.61) NPY2RNPY4RNPY5RNPY1RNTSR1
SCHEMBL31000874 0.87 NPY2R (0.64) HCRTR1HCRTR2NPY2RNPY4RNPY5R
SCHEMBL30435444 0.87 OPRD1 (0.67) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30648484 0.86 CALCR (0.62) HCRTR1HCRTR2NPY2RNPY4RNPY5R
SCHEMBL30824294 0.86 NPY2R (0.66) NPY2RNPY4RNPY5RNPY1RCALCR
Neurotensin SCHEMBL29357707 0.86 NTSR1 (0.70) HCRTR1HCRTR2NPY1RNTSR1OPRM1
Neurotensin SCHEMBL29851748 0.86 NTSR1 (0.70) HCRTR1HCRTR2NPY1RNTSR1OPRM1
SCHEMBL31000890 0.86 NPY2R (0.63) HCRTR1HCRTR2NPY2RNPY4RNPY5R
SCHEMBL30607403 0.86 CALCR (0.67) HCRTR1HCRTR2NPY2RNPY4RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12624002-B2 Dimers for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-05-12 — — US disclosed
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 — — US disclosed
US-12595233-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-07 — — US disclosed
US-20260070894-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-03-12 — — US disclosed
US-20250326866-A1 TRANSFERRIN RECEPTOR TARGETING PEPTIDE OLIGONUCLEOTIDE COMPLEXES AND METHODS OF USE THEREOF BLAZE BIOSCIENCE INC (US) 2025-10-23 — — US disclosed
US-12351573-B2 Compounds for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2025-07-08 — — US disclosed
US-20250195673-A1 COMPOSITIONS AND METHODS FOR SELECTIVE DEPLETION OF TARGET MOLECULES Blaze Bioscience, Inc. 2025-06-19 — — US disclosed
EP-3782649-B1 BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS ASCENDIS PHARMA AS (DK) 2025-05-14 — — EP disclosed
EP-3893913-B1 TRANSFERRIN RECEPTOR TARGETING PEPTIDES FRED HUTCHINSON CANCER CENTER (US) 2025-03-26 — — EP disclosed
US-20250051830-A1 MEMBRANE-EMBEDDED NANOPORE AND USES THEREOF ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2025-02-13 — — US disclosed
US-20220372022-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2022-11-24 — — US disclosed
US-20220306577-A1 THIOSEMICARBAZATES AND USES THEREOF FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2022-09-29 — — US disclosed
US-11440881-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2022-09-13 — — US disclosed
US-11414405-B2 Compounds for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2022-08-16 — — US disclosed
WO-2022125673-A1 CELL-PENETRATING PEPTIDES AND PEPTIDE COMPLEXES AND METHODS OF USE FRED HUTCHINSON CANCER RESEARCH CENTER (US) 2022-06-16 — — WO disclosed
EP-4011396-A1 RELEASABLE CONJUGATES QuiaPEG Pharmaceuticals AB (SE) 2022-06-15 — — EP disclosed
WO-2022115715-A1 COMPOSITIONS AND METHODS FOR SELECTIVE DEPLETION OF TARGET MOLECULES FRED HUTCHINSON CANCER RESEARCH CENTER (US) 2022-06-02 — — WO disclosed
US-11331393-B2 Renal-homing peptide conjugates and methods of use thereof Blaze Bioscience, Inc. (US) 2022-05-17 — — US disclosed
EP-3966223-A1 PEPTIDOMIMETIC AGENTS, SYNTHESIS AND USES THEREOF The Feinstein Institutes for Medical Research (US) 2022-03-16 — — EP disclosed
EP-3966201-A1 THIOSEMICARBAZATES AND USES THEREOF The Feinstein Institutes for Medical Research (US) 2022-03-16 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12351573-B2 Compounds for use in synthesis of peptidomimetics DNPEP, NPEPPS, PAM HCRTR1 1287/4885HCRTR2 890/4885NPY2R 501/4885
US-11440881-B2 Thiosemicarbazates and uses thereof TST, ABAT, AADAC HCRTR1 3576/4885HCRTR2 4204/4885NPY2R 3978/4885
US-12624002-B2 Dimers for use in synthesis of peptidomimetics GLUL, ARGLU1, ASNS HCRTR1 744/4885HCRTR2 648/4885NPY2R 111/4885
US-11414405-B2 Compounds for use in synthesis of peptidomimetics DNPEP, NPEPPS, PAM HCRTR1 1287/4885HCRTR2 890/4885NPY2R 501/4885
US-11331393-B2 Renal-homing peptide conjugates and methods of use thereof CXCL12, ATP6V1B1, VIP HCRTR1 2959/4885HCRTR2 2595/4885NPY2R 674/4885
US-20260070894-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS NPR1, NGLY1, DDAH1 HCRTR1 112/4885HCRTR2 127/4885NPY2R 150/4885
US-12595233-B2 Thiosemicarbazates and uses thereof TST, THRB, HSPB1 HCRTR1 2440/4885HCRTR2 3295/4885NPY2R 1754/4885
US-20220372022-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS DNPEP, NPEPPS, PAM HCRTR1 1287/4885HCRTR2 890/4885NPY2R 501/4885
US-20250326866-A1 TRANSFERRIN RECEPTOR TARGETING PEPTIDE OLIGONUCLEOTIDE COMPLEXES AND METHODS OF USE THEREOF TFRC, TEK, FOLR1 HCRTR1 1622/4885HCRTR2 1751/4885NPY2R 529/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT HCRTR1 968/4885HCRTR2 2037/4885NPY2R 791/4885
US-20220306577-A1 THIOSEMICARBAZATES AND USES THEREOF TST, ABAT, AADAC HCRTR1 3576/4885HCRTR2 4204/4885NPY2R 3978/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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