Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 known ✓ | P14867 | 1/20 | 0.43 |
| ▸ | GABRB2 known ✓ | P47870 | 1/20 | 0.43 |
| ▸ | HTR2C known ✓ | P28335 | 2/20 | 0.38 |
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.38 |
| ▸ | HTR2B known ✓ | P41595 | 1/20 | 0.38 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.34 |
| ▸ | PIK3CA known ✓ | P42336 | 1/20 | 0.33 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.33 |
| ▸ | CASR known ✓ | P41180 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | CD44 | P16070 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3638609 | 0.98 | TRPA1 (0.46) | TRPA1ATMGABRA1GABRB2HTR2C | |
| Water SCHEMBL10401166 | 0.95 | TRPA1 (0.44) | TRPA1ATMGABRA1GABRB2HTR2C | |
| Acetic Acid SCHEMBL2129191 | 0.86 | TRPA1 (0.42) | TRPA1ATMGABRA1GABRB2CYP3A4 | |
| SCHEMBL11968999 | 0.84 | TRPA1 (0.46) | TRPA1ATMGABRA1GABRB2HTR2C | |
| SCHEMBL31355209 | 0.84 | TRPA1 (0.46) | TRPA1ATMGABRA1GABRB2HTR2C | |
| Hydrochloric Acid SCHEMBL23886258 | 0.81 | TDP1 (0.44) | TRPA1ATMGABRA1GABRB2HTR2C | |
| Hydrochloric Acid SCHEMBL136350 | 0.81 | TDP1 (0.44) | TRPA1ATMGABRA1GABRB2HTR2C | |
| Hydrochloric Acid SCHEMBL30017987 | 0.78 | GABRA1 (0.41) | TRPA1ATMGABRA1GABRB2HTR2C | |
| Hydrochloric Acid SCHEMBL23886141 | 0.78 | CHRM3 (0.36) | GABRA1GABRB2HTR2CHTR2BCYP3A4 | |
| Hydrochloric Acid SCHEMBL23886264 | 0.78 | GABRA1 (0.41) | TRPA1ATMGABRA1GABRB2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003991-A | Epoxy resin, preparation method thereof and resin composition | 华为技术有限公司 | 2023-11-07 | — | — | CN | disclosed |
| WO-2023208180-A1 | EPOXY RESIN, METHOD FOR PREPARING SAME, AND RESIN COMPOSITION THEREOF | 华为技术有限公司 | 2023-11-02 | — | — | WO | disclosed |
| CN-115677980-A | Epoxy resin, preparation method thereof and resin composition | 华为技术有限公司 | 2023-02-03 | — | — | CN | disclosed |
| US-20180002562-A1 | LOW-TEMPERATURE-CURABLE CROSS-SECTION REPAIR MATERIAL, AND CROSS-SECTION REPAIRING METHOD USING THE SAME | SHOWA DENKO K.K. (JP) | 2018-01-04 | — | — | US | disclosed |
| EP-3260479-A1 | LOW-TEMPERATURE-CURABLE CROSS-SECTION REPAIR MATERIAL, AND CROSS-SECTION REPAIR METHOD USING SAME | Showa Denko K.K. (JP) | 2017-12-27 | — | — | EP | disclosed |
| US-7767778-B2 | Polyurethane powder coating compositions that do not split off blocking agents and have a low stoving temperature | BAYER MATERIALSCIENCE AG (DE) | 2010-08-03 | — | — | US | disclosed |
| CN-1309783-C | Epoxy resin compositing, its solidification product, new-type epoxy resin, phenol compound, and its preparation method | DAINIPPON INK & CHEMICALS (JP) | 2007-04-11 | — | — | CN | disclosed |
| EP-1275673-B1 | Epoxy resin composition, cured article thereof, novel epoxy resin, novel phenol compound, and process for preparing the same | DAINIPPON INK & CHEMICALS (JP) | 2006-08-23 | — | — | EP | disclosed |
| US-20050222364-A1 | Polyurethane powder coating compositions that do not split off blocking agents and have a low stoving temperature | COVESTRO DEUTSCHLAND AG (DE) | 2005-10-06 | — | — | US | disclosed |
| US-6784228-B2 | HEAT RESISTANCE, WATERPROOFING, DIMENSIONAL STABILITY, MULTILAYER LAMINATE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2004-08-31 | — | — | US | disclosed |
| EP-0884342-B1 | Resin for coating formation and method for producing the same | UNITIKA LTD (JP) | 2003-09-24 | — | — | EP | disclosed |
| US-20030092852-A1 | Epoxy resin composition, cured article thereof, novel epoxy resin, novel phenol compound, and process for preparing the same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2003-05-15 | — | — | US | disclosed |
| CN-1414031-A | Epoxy resin compositing, its solidification product, new-type epoxy resin, phenol compound, and its preparation method | DAINIPPON INK & CHEMICALS (JP) | 2003-04-30 | — | — | CN | disclosed |
| EP-1275673-A2 | Epoxy resin composition, cured article thereof, novel epoxy resin, novel phenol compound, and process for preparing the same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2003-01-15 | — | — | EP | disclosed |
| US-5902872-A | POLYARYLATE COMPRISING 2,2-BIS/3-METHYL-4-HYDROXYPHENYL/PROPANE UNITS, TEREPHTHALIC ACID UNITS AND ISOPHTHALIC ACID UNITS, HAVING SPECIFIED INHERENT VISCOSITY | UNITIKA, LTD. (JP) | 1999-05-11 | — | — | US | disclosed |
| EP-0884342-A1 | Resin for coating formation and method for producing the same | UNITIKA LTD. (JP) | 1998-12-16 | — | — | EP | disclosed |
| EP-0160642-B1 | POLYMERIC LIGHT STABILIZERS CONTAINING POLYALKYLPIPERIDINE GROUPS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-02-08 | — | — | EP | disclosed |
| WO-1985001734-A1 | POLYMERIC LIGHT STABILIZERS CONTAINING POLYALKYLPIPERIDINE GROUPS | FORD MOTOR COMPANY (US) | 1985-04-25 | — | — | WO | disclosed |
| US-4480084-A | EXPOY RESING, POLYALKYLPIPERIDINE, AND HYDROXY FUNCTIONAL MONOMER | FORD MOTOR COMPANY (US) | 1984-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092852-A1 | Epoxy resin composition, cured article thereof, novel epoxy resin, novel phenol compound, and process for preparing the same | KDM5C, KDM5B, KDM4C | GABRA1 1190/4885GABRB2 1342/4885HTR2C 3077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.