SCHEMBL3628615

SCHEMBL3628615

CC(=O)CCC(=O)C(C)(C)C

nearest known ligand 0.59

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.59
LMNA P02545 1/20 0.48
SLC15A2 Q16348 1/20 0.48
TDP1 Q9NUW8 1/20 0.35
ACHE P22303 1/20 0.35
PAOX Q6QHF9 1/20 0.35
TRPA1 O75762 1/20 0.33
KMT2A Q03164 1/20 0.33
GAA P10253 1/20 0.33
HSD11B1 P28845 1/20 0.30
CHRM1 P11229 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL755487 0.87 KMT2A (0.39) ALDH1A1KMT2AHSD11B1CHRM1
SCHEMBL16185829 0.83 PAOX (0.48) ALDH1A1LMNASLC15A2ACHEPAOX
SCHEMBL10017821 0.83 ALDH1A1 (0.45) ALDH1A1LMNASLC15A2TDP1ACHE
SCHEMBL11253721 0.82 ALDH1A1 (0.35) ALDH1A1KMT2AHSD11B1
SCHEMBL15146906 0.81 PAOX (0.52) ALDH1A1LMNASLC15A2ACHEPAOX
SCHEMBL18056080 0.81 PAOX (0.52) ALDH1A1LMNASLC15A2ACHEPAOX
SCHEMBL16233152 0.78 ALDH1A1 (0.32) ALDH1A1TDP1KMT2A
SCHEMBL24103118 0.78 ALDH1A1 (0.40) ALDH1A1LMNASLC15A2KMT2AGAA
SCHEMBL10001 0.77
SCHEMBL409946 0.77 EGLN1 (0.53) LMNASLC15A2KMT2ACHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12595325-B2 Process for the preparation of a multimodal polyethylene BOREALIS AG (AT) 2026-04-07 US disclosed
US-12583955-B2 Metallocene complexes and catalysts made therefrom BOREALIS AG (AT) 2026-03-24 US disclosed
US-12319698-B2 Proteasome activity enhancing compounds Kineta, Inc. (US) 2025-06-03 US disclosed
US-20250171481-A1 METALLOCENE COMPLEXES AND CATALYSTS MADE THEREFROM BOREALIS AG (AT) 2025-05-29 US disclosed
CN-116194493-B Metallocene complexes and catalysts prepared therefrom 博里利斯股份公司 2025-04-22 CN disclosed
CN-112585132-B Proteasome activity enhancing compounds 优曼尼蒂公司 2025-02-28 CN disclosed
US-20240002560-A1 PROCESS FOR THE PREPARATION OF A MULTIMODAL POLYETHYLENE BOREALIS AG (AT) 2024-01-04 US disclosed
US-11814391-B2 Macrocyclic compounds for the treatment of medical disorders ACHILLION PHARMACEUTICALS, INC. (US) 2023-11-14 US disclosed
US-20230357199-A1 ARYL, HETEROARYL, AND HETEROCYCLIC PHARMACEUTICAL COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS ACHILLION PHARMACEUTICALS, INC. 2023-11-09 US disclosed
US-20230322853-A1 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PROLIFERATIVE DISEASES AND DISORDERS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2023-10-12 US disclosed
US-20100216915-A1 Levulinic acid ester derivatives as reactive plasticizers and coalescent solvents ARCHER-DANIELS-MIDLAND COMPANY (US) 2010-08-26 US disclosed
US-20100179181-A1 PHARMACEUTICAL FORMULATIONS OF BIODEGRADABLE BIOCOMPATIBLE CAMPTOTHECIN-POLYMER CONJUGATES MERSANA THERAPEUTICS, INC. (US) 2010-07-15 US disclosed
US-7695863-B2 rechargeable batteries having excellent battery cycle properties, electrical capacity and storage characteristic during charging, comprising electrodes and a nonaqueous electrolytic solution containing a dicarbonyl compound as an additive UBE INDUSTRIES, LTD. (JP) 2010-04-13 US disclosed
CN-100566005-C The lithium secondary battery of nonaqueous electrolyte solution and this solution of use UBE INDUSTRIES (JP) 2009-12-02 CN disclosed
US-7576175-B2 Amino acid terminated diphenylurea derivatives; display high binding affinity, specificity, and stability; use in treating cancer, inflammatory diseases, and autoimmune diseases THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-08-18 US disclosed
US-20080102377-A1 rechargeable batteries having excellent battery cycle properties, electrical capacity and storage characteristic during charging, comprising electrodes and a nonaqueous electrolytic solution containing a dicarbonyl compound as an additive UBE INDUSTRIES, LTD (JP) 2008-05-01 US disclosed
WO-2008031016-A2 HETEROCYCLIC LIGANDS FOR INTEGRIN IMAGING AND THERAPY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-03-13 WO disclosed
CN-101091283-A Nonaqueous electrolytic solution and lithium secondary battery using the same UBE INDUSTRIES (JP) 2007-12-19 CN disclosed
US-20070015927-A1 New phosphoramidite compounds POSTECH FOUNDATION (KR) 2007-01-18 US disclosed
US-20060019900-A1 Alpha-4 beta-1 integrin ligands for imaging and therapy THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230322853-A1 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PROLIFERATIVE DISEASES AND DISORDERS POLI, PCNA, POLH ALDH1A1 3968/4885LMNA 487/4885SLC15A2 4194/4885
US-20100216915-A1 Levulinic acid ester derivatives as reactive plasticizers and coalescent solvents EPM2A, ALAD, GABRD ALDH1A1 635/4885LMNA 908/4885SLC15A2 1196/4885
US-20100179181-A1 PHARMACEUTICAL FORMULATIONS OF BIODEGRADABLE BIOCOMPATIBLE CAMPTOTHECIN-POLYMER CONJUGATES PAICS, TK1, PKLR ALDH1A1 925/4885LMNA 942/4885SLC15A2 680/4885
US-20070015927-A1 New phosphoramidite compounds TYMP, POLRMT, POLI ALDH1A1 4594/4885LMNA 3045/4885SLC15A2 3641/4885
US-12319698-B2 Proteasome activity enhancing compounds PSMG3, PSME3, PSMC4 ALDH1A1 3438/4885LMNA 1575/4885SLC15A2 3957/4885
US-12583955-B2 Metallocene complexes and catalysts made therefrom OPRM1, NR4A1, RRM1 ALDH1A1 941/4885LMNA 1872/4885SLC15A2 3115/4885
US-20060019900-A1 Alpha-4 beta-1 integrin ligands for imaging and therapy ITGA4, ITGB4, ITGA1 ALDH1A1 1238/4885LMNA 2391/4885SLC15A2 1765/4885
US-20230357199-A1 ARYL, HETEROARYL, AND HETEROCYCLIC PHARMACEUTICAL COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS CFD, TFPI, CFH ALDH1A1 2338/4885LMNA 2135/4885SLC15A2 2273/4885
US-12595325-B2 Process for the preparation of a multimodal polyethylene OPRM1, SIGMAR1, GPS1 ALDH1A1 3615/4885LMNA 1361/4885SLC15A2 3515/4885
US-20250171481-A1 METALLOCENE COMPLEXES AND CATALYSTS MADE THEREFROM OPRM1, NR4A1, POLM ALDH1A1 1657/4885LMNA 1437/4885SLC15A2 2466/4885
US-11814391-B2 Macrocyclic compounds for the treatment of medical disorders CFD, TFPI, CFH ALDH1A1 4659/4885LMNA 816/4885SLC15A2 3491/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.