Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.65 |
| ▸ | HDAC8 known ✓ | Q9BY41 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.93 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.93 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.67 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | CA12 | O43570 | 1/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | CA4 | P22748 | 1/20 | 0.65 |
| ▸ | CA6 | P23280 | 1/20 | 0.65 |
| ▸ | CA7 | P43166 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | CA9 | Q16790 | 1/20 | 0.65 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | NR4A1 | P22736 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL22453 | 1.00 | ALDH1A1 (0.93) | ALDH1A1ALOX15AKR1C3NAPRTKDM4E | |
| Phthalic Acid SCHEMBL5036784 | 1.00 | ALDH1A1 (0.93) | ALDH1A1ALOX15AKR1C3NAPRTKDM4E | |
| Phthalic Acid SCHEMBL29396592 | 1.00 | ALDH1A1 (0.93) | ALDH1A1ALOX15AKR1C3NAPRTKDM4E | |
| Phthalic Acid SCHEMBL29037475 | 0.97 | ALDH1A1 (0.88) | ALDH1A1ALOX15AKR1C3NAPRTKDM4E | |
| Phthalic Acid SCHEMBL10891138 | 0.97 | ALDH1A1 (0.88) | ALDH1A1ALOX15AKR1C3NAPRTKDM4E | |
| Phthalic Acid SCHEMBL29037477 | 0.97 | ALDH1A1 (0.88) | ALDH1A1ALOX15AKR1C3NAPRTKDM4E | |
| Phthalic Acid SCHEMBL28656910 | 0.97 | ALDH1A1 (0.88) | ALDH1A1ALOX15AKR1C3NAPRTKDM4E | |
| Phthalic Acid SCHEMBL28625830 | 0.97 | ALDH1A1 (0.88) | ALDH1A1ALOX15AKR1C3NAPRTKDM4E | |
| Phthalic Acid SCHEMBL4585517 | 0.97 | ALDH1A1 (0.88) | ALDH1A1ALOX15AKR1C3NAPRTKDM4E | |
| Phthalic Acid SCHEMBL28286107 | 0.97 | ALDH1A1 (0.88) | ALDH1A1ALOX15AKR1C3NAPRTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 864 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4722284-A1 | LOW MELTING CARBOXAMIDE HALS FOR IMPROVED STABILIZATION OF POLYMERS OR RESINS | CLARIANT INTERNATIONAL LTD (CH) | 2026-04-08 | — | — | EP | claimed |
| CN-118685634-A | Separation and recovery method for lithium ions in retired waste lithium batteries based on nanofiltration-reverse osmosis method | 广东奥斯博膜材料技术有限公司 | 2024-09-24 | — | — | CN | claimed |
| CN-118236346-A | Lung-targeted ionizable lipid nanoparticle, and preparation method and application thereof | 北京科技大学 | 2024-06-25 | — | — | CN | claimed |
| CN-118183749-A | Nano silicon @ SiOx/MXene composite anode material and preparation method thereof | 昆明理工大学 | 2024-06-14 | — | — | CN | claimed |
| US-20240180832-A1 | COMPOUND, LIPOSOME, AND USES THEREOF | BEIJING INSTITUTE OF TECHNOLOGY (CN) | 2024-06-06 | — | — | US | claimed |
| CN-118063794-A | Preparation method of lignin containing primary amine groups | 新疆农业大学 | 2024-05-24 | — | — | CN | claimed |
| CN-117959942-A | Preparation method of high-flux stain-resistant composite membrane | 浙江理工大学 | 2024-05-03 | — | — | CN | claimed |
| CN-117903879-A | Cleaning solution for removing residues after etching of copper process aluminum pad | 湖北兴福电子材料股份有限公司 | 2024-04-19 | — | — | CN | claimed |
| CN-117886685-A | 1, 3-diaryl formyl benzene compound and preparation method and application thereof | 浙江工业大学 | 2024-04-16 | — | — | CN | claimed |
| EP-4342881-A1 | COMPOUND, LIPOSOME, AND USES THEREOF | Beijing Institute Of Technology (CN) | 2024-03-27 | — | — | EP | claimed |
| CN-1800229-A | Preparation of monodispersion high molecular nanometer sphere using envelop virus as template | UNIV TIANJIN TECHNOLOGY (CN) | 2006-07-12 | — | — | CN | claimed |
| EP-1341830-B1 | METHOD FOR PRODUCING THERMOPLASTIC MOLDING MATERIALS CONTAINING RUBBER | BASF AG (DE) | 2006-01-11 | — | — | EP | claimed |
| US-20050041569-A1 | Optical disk | LG ELECTRONICS INC. | 2005-02-24 | — | — | US | claimed |
| US-20040102564-A1 | Method for producing thermoplastic molding materials containing rubber | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-27 | — | — | US | claimed |
| EP-1045291-A2 | Method of improving the etch resistance of photoresists | Infineon Technologies North America Corp. (US) | 2000-10-18 | — | — | EP | claimed |
| CN-1264061-A | Method for improving photoetching rubber elching resistant | YINFENNIAN TECHNOLOGY NORTH AM (US) | 2000-08-23 | — | — | CN | claimed |
| EP-0611326-B1 | METHOD FOR PRODUCING NANOCAPSULES WITH CROSS-LINKED PROTEIN-BASED WALLS, NANOCAPSULES THEREBY OBTAINED, AND COSMETIC, PHARMACEUTICAL AND FOOD COMPOSITIONS USING SAME | COLETICA (FR) | 1997-08-06 | — | — | EP | claimed |
| EP-0513252-A1 | HIGH PURITY AROMATIC POLYESTER, A FILM AND OTHER PRODUCTS AND DEVICES CONTAINING SUCH POLYESTER AS WELL AS A PROCESS FOR PREPARING SUCH FILM | ISONOVA TECHNISCHE INNOVATIONEN GES.M.B.H. (AT) | 1992-11-19 | — | — | EP | claimed |
| WO-1992003493-A1 | HIGH PURITY AROMATIC POLYESTER, A FILM AND OTHER PRODUCTS AND DEVICES CONTAINING SUCH POLYESTER AS WELL AS A PROCESS FOR PREPARING SUCH FILM | ISONOVA TECHNISCHE INNOVATIONEN GESELLSCHAFT M.B.H. (AT) | 1992-03-05 | — | — | WO | claimed |
| US-4868265-A | Polyanhydride process from bis(trimethylsilyl) ester of dicarboxylic acid | HOECHST CELANESE CORP. (US) | 1989-09-19 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240180832-A1 | COMPOUND, LIPOSOME, AND USES THEREOF | LIPA, LIPC, PNLIP | CA2 4841/4885HDAC8 2423/4885ALDH1A1 3790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.